Macrophages in the Human Body

Through recent researches, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic population with wide range phenotypes, and tissue-specific functions, such as bone resorption, extracellular matrix production, red blood cells and bacteria removal, among others. Through innate immune receptors macrophages can modulate several pathways that culminate in the production of various types of inflammatory mediators such as chemokines, cytokines, oxygen reactive species, and lipid mediators which ultimately altered the behavior of other cells. Moreover, environment signals modify and induce metabolic reprograming that it alters phenotype and functions Macrophages in the Human Body: A Tissue Level Approach presents a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics. It covers translational aspects where there is research support to indicate the therapeutic potential. Covers translational aspects where there is research support to indicate potential therapeutic potential Aims at presenting a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics Introduces Macrophages generally and dive into the organ/tissue/specific representations covering their phenotype, function, and metabolic characteristics Brings updated aspects of macrophages biology

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  • Author : Niels Olson Saraiva Camara
  • Publisher : Academic Press
  • Pages : 341 pages
  • ISBN : 0128213868
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKMacrophages in the Human Body

Macrophages in the Human Body

Macrophages in the Human Body
  • Author : Niels Olson Saraiva Camara,Tarcio Teodoro Braga
  • Publisher : Academic Press
  • Release : 01 June 2021
GET THIS BOOKMacrophages in the Human Body

Through recent researches, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic population with wide range phenotypes, and tissue-specific functions, such as bone resorption, extracellular matrix production, red blood cells and bacteria removal, among others. Through innate immune receptors macrophages can modulate several pathways that culminate in the production of various types of inflammatory

The Resolution of Inflammation

The Resolution of Inflammation
  • Author : Adriano Rossi,Deborah A. Sawatzky
  • Publisher : Springer Science & Business Media
  • Release : 17 March 2008
GET THIS BOOKThe Resolution of Inflammation

This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.

Fascia: The Tensional Network of the Human Body - E-Book

Fascia: The Tensional Network of the Human Body - E-Book
  • Author : Robert Schleip,Thomas W. Findley,Leon Chaitow,Peter Huijing
  • Publisher : Elsevier Health Sciences
  • Release : 08 December 2021
GET THIS BOOKFascia: The Tensional Network of the Human Body - E-Book

The role of the fascia in musculoskeletal conditions and as a body-wide communication system is now well established. Fascia: The Tensional Network of the Human Body constitutes the most comprehensive foundational textbook available that also provides the latest research theory and science around fascia and their function. This book is unique in offering consensus from scientists and clinicians from across the world and brings together the work of the group behind the international Fascia Research Congress. It is ideal for

Biomaterials in Regenerative Medicine and the Immune System

Biomaterials in Regenerative Medicine and the Immune System
  • Author : Laura Santambrogio
  • Publisher : Springer
  • Release : 04 September 2015
GET THIS BOOKBiomaterials in Regenerative Medicine and the Immune System

The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as

Macrophages

Macrophages
  • Author : Malgorzata Kloc
  • Publisher : Springer
  • Release : 26 April 2017
GET THIS BOOKMacrophages

This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important components of modern medicine. Macrophages are evolutionarily conserved phagocytotic cells. In recent years macrophages have emerged as one of the most versatile cells of immune system, which, depending on the milieu and circumstance, participate in development or inhibition

Macrophages: Biology and Role in the Pathology of Diseases

Macrophages: Biology and Role in the Pathology of Diseases
  • Author : Subhra K. Biswas,Alberto Mantovani
  • Publisher : Springer
  • Release : 12 November 2014
GET THIS BOOKMacrophages: Biology and Role in the Pathology of Diseases

Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and promoting resolution of inflammation. On the other hand, they contribute to essential trophic functions such as neural patterning, bone morphogenesis and ductal branching in mammary glands. Thus, macrophages are extremely versatile cells that can respond efficiently to

The Immune Response to Implanted Materials and Devices

The Immune Response to Implanted Materials and Devices
  • Author : Bruna Corradetti
  • Publisher : Springer
  • Release : 30 November 2016
GET THIS BOOKThe Immune Response to Implanted Materials and Devices

This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development

The M2 Macrophage

The M2 Macrophage
  • Author : Tamás Röszer
  • Publisher : Springer Nature
  • Release : 03 August 2020
GET THIS BOOKThe M2 Macrophage

Macrophages are core components of the innate immune system. Once activated, they may have either pro- or anti-inflammatory effects that include pathogen killing, safe disposal of apoptotic cells or tissue renewal. The activation state of macrophages is conceptualized by the so-called M1/M2 model of polarization. M2 macrophages are not simply antagonists of M1 macrophages; rather, they represent a network of tissue resident macrophages with roles in tissue development and organ homeostasis. M2 macrophages govern functions at the interfaces of

Chronic Liver Failure

Chronic Liver Failure
  • Author : Pere Ginès,Patrick S Kamath,Vicente Arroyo
  • Publisher : Springer Science & Business Media
  • Release : 03 November 2010
GET THIS BOOKChronic Liver Failure

Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their