Mesenchymal Stem Cell Derived Exosomes

Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies

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  • Author : Yaoliang Tang
  • Publisher : Academic Press
  • Pages : 288 pages
  • ISBN : 0128004975
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKMesenchymal Stem Cell Derived Exosomes

Mesenchymal Stem Cell Derived Exosomes

Mesenchymal Stem Cell Derived Exosomes
  • Author : Yaoliang Tang,Buddhadeb Dawn
  • Publisher : Academic Press
  • Release : 02 September 2015
GET THIS BOOKMesenchymal Stem Cell Derived Exosomes

Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the

Extracellular Vesicles

Extracellular Vesicles
  • Author : Dr Wojciech Chrzanowski,Professor Chwee Teck Lim,Dr Sally Yunsun Kim
  • Publisher : Royal Society of Chemistry
  • Release : 29 October 2021
GET THIS BOOKExtracellular Vesicles

Extracellular and biofluids vesicles (EVs) are highly specialised yet ubiquitous nanoscale messengers secreted by cells. With the development of stem cell engineering, EVs promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field. Covering basic cell biology, including EV production and intracellular communication, this book will provide material scientists and engineers with a foundation to the necessary biology. The

Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
  • Author : Lucas G. Chase,Mohan C Vemuri
  • Publisher : Springer Science & Business Media
  • Release : 12 December 2012
GET THIS BOOKMesenchymal Stem Cell Therapy

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host

Exosomes in Cardiovascular Diseases

Exosomes in Cardiovascular Diseases
  • Author : Junjie Xiao,Sanda Cretoiu
  • Publisher : Springer
  • Release : 19 September 2017
GET THIS BOOKExosomes in Cardiovascular Diseases

The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers

Effect Of Combined Platelet-Rich Plasma And Mesenchymal Stem Cell-Derived Exosomes On Chondrocyte Gene Expression

Effect Of Combined Platelet-Rich Plasma And Mesenchymal Stem Cell-Derived Exosomes On Chondrocyte Gene Expression
  • Author : Anonim
  • Publisher : Unknown Publisher
  • Release : 19 January 2022
GET THIS BOOKEffect Of Combined Platelet-Rich Plasma And Mesenchymal Stem Cell-Derived Exosomes On Chondrocyte Gene Expression

INTRODUCTION: Platelet-rich plasma (PRP) and mesenchymal stem cells (MSCs) serve as two of the most popular potential therapies to enhance cartilage regeneration. Platelets contain alpha granules that house a plethora of growth factors, cytokines, and other molecules that may potentiate tissue healing. Some studies posit that MSCs exert regenerative effects via paracrine signaling [1] which may be mediated by exosomes. Defined as extracellular vesicles released from the fusion of a cytosolic multivesicular body with the cell membrane, exosomes have been implicated

Regenerative Potential of Mesenchymal Stem Cell Derived Exosomes

Regenerative Potential of Mesenchymal Stem Cell Derived Exosomes
  • Author : Andrew P. Wong
  • Publisher : Unknown Publisher
  • Release : 19 January 2022
GET THIS BOOKRegenerative Potential of Mesenchymal Stem Cell Derived Exosomes

Bone defects are a pervasive complication arising from many clinical conditions, both mechanical and pathological. Current treatments for large bony defects focus on applying bone grafts or synthetic materials to the defect area. Cell-based-and especially stem-cell-therapies have advanced greatly thanks to increasing attention focused on their ability to generate new tissues in situ with biomechanical properties approaching that of native tissue, but they suffer from their own shortcomings as well. Exosomes have been shown to play critical roles in cell-signaling

Role of Exosomes in Biological Communication Systems

Role of Exosomes in Biological Communication Systems
  • Author : Faisal A. Alzahrani,Islam M. Saadeldin
  • Publisher : Springer Nature
  • Release : 20 November 2020
GET THIS BOOKRole of Exosomes in Biological Communication Systems

This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential

Perinatal Stem Cells

Perinatal Stem Cells
  • Author : Zhong Chao Han,Tsuneo A. Takahashi,Zhibo Han,Zongjin Li
  • Publisher : Springer
  • Release : 06 March 2019
GET THIS BOOKPerinatal Stem Cells

This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury. Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be cultured indefinitely ex vivo, and can differentiate into three germ layers, ethical issues, the teratoma formation of ESCs and

Mesenchymal Stem Cells

Mesenchymal Stem Cells
  • Author : Massimiliano Gnecchi
  • Publisher : Humana Press
  • Release : 26 May 2018
GET THIS BOOKMesenchymal Stem Cells

This volume aims to outline the current status of the Mesenchymal Stem Cells(MSC) field in regenerative medicine and to propose clear and reproducible protocols to better define the identity, function and use of these cells that are today, more than ever, “under the spotlight”. Mesenchymal Stem Cells: Methods and Protocols, Second Edition is organized into four sections. The first guides the reader through a series of state-of-the-art reviews summarizing the use of MSC for the treatment of various diseases.

Cardiac Regeneration

Cardiac Regeneration
  • Author : Masaki Ieda,Wolfram-Hubertus Zimmermann
  • Publisher : Springer
  • Release : 27 October 2017
GET THIS BOOKCardiac Regeneration

This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when,

Mesenchymal Stem Cell-derived Exosomes Ameliorate Disease in a Model of Relapsing-remitting Multiple Sclerosis

Mesenchymal Stem Cell-derived Exosomes Ameliorate Disease in a Model of Relapsing-remitting Multiple Sclerosis
  • Author : Oliver Yuan
  • Publisher : Unknown Publisher
  • Release : 19 January 2022
GET THIS BOOKMesenchymal Stem Cell-derived Exosomes Ameliorate Disease in a Model of Relapsing-remitting Multiple Sclerosis

Multiple sclerosis (MS) is a demyelinating autoimmune disease that results in neurological disability. There are now 15 medications approved to treat relapsing-remitting MS, however, none of the available therapies halts disease progression or directly reverses central nervous system damage. The two salient features of MS pathology involve an over-activation of the inflammatory response in the central nervous system (CNS) and auto-antibody targeting of the myelin sheath that insulates axons. Remyelination in MS does not occur due to the lack of differentiation

Exosomes, Stem Cells and MicroRNA

Exosomes, Stem Cells and MicroRNA
  • Author : Karl L. Mettinger,Pranela Rameshwar,Vinod Kumar
  • Publisher : Springer
  • Release : 12 May 2018
GET THIS BOOKExosomes, Stem Cells and MicroRNA

This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well

The Biology and Therapeutic Application of Mesenchymal Cells - Set

The Biology and Therapeutic Application of Mesenchymal Cells - Set
  • Author : Kerry Atkinson
  • Publisher : John Wiley & Sons
  • Release : 17 January 2017
GET THIS BOOKThe Biology and Therapeutic Application of Mesenchymal Cells - Set

The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited,

Regenerative Medicine: Laboratory to Clinic

Regenerative Medicine: Laboratory to Clinic
  • Author : Asok Mukhopadhyay
  • Publisher : Springer
  • Release : 21 September 2017
GET THIS BOOKRegenerative Medicine: Laboratory to Clinic

This book discusses the two different cellular approaches that are pursued in regenerative medicine: cell therapy and tissue engineering. It examines in detail the therapeutic application of hematopoietic stem cells in marrow regeneration, multi-potent mesenchymal stem cells (MSCs), also referred to as mesenchymal stromal cells. The interest in MSCs can be seen in more than 150 clinical trials, some of which have progressed to Phase III, despite the cells’ limited differentiation potential. The book also explores how embryonic stem (ES) cells,