Metabolic Phenotyping in Personalized and Public Healthcare

Metabolic Phenotyping in Personalized and Public Healthcare provides information on the widespread recognition that a personalized or stratified approach to patient treatment may offer a more efficient and effective healthcare solution than phenotype-led approaches. In order to achieve that objective, a deep personal description is required at the level of the genome, proteome, metabolome, or preferably a combination of these aided by technology. This book, edited and written by the outstanding luminaries of this evolving field, evaluates metabolic profiling and its uses across personalized and population healthcare, while also covering the advent of new technology fields, such as surgical metabonomics. In addition, the text presents specific examples of where this technology has been used clinically and with efficacy, pointing towards a framework and protocol for usage as it hits the clinical mainstream. Translates the conjunction of new surgical tools for intraoperative, real-time, metabolite evaluation and direct analysis of biofluid samples into novel options for augmented clinical decision-making Discusses longitudinal sampling from individual patients for stratified medicine Covers high resolution analytical spectroscopy and sophisticated computational modelling for prediction of adverse reactions in critical care scenarios, prognostic evaluation of cancer from biofluidism, and prognostic prediction of metabolism or response of patients to pharmaceutical interventions Encapsulates recent technology options for broader population profiling considerations, in particular, the metabolome-wide association studies (MWAS) that aid the translational researcher in identifying metabolic patterns associated with disease Foreword written by Professor Dame Sally Davies who is the Chief Medical Officer for England

Produk Detail:

  • Author : Jeremy Nicholson
  • Publisher : Academic Press
  • Pages : 428 pages
  • ISBN : 0128004142
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKMetabolic Phenotyping in Personalized and Public Healthcare

Metabolic Phenotyping in Personalized and Public Healthcare

Metabolic Phenotyping in Personalized and Public Healthcare
  • Author : Jeremy Nicholson,Ara Darzi,Elaine Holmes,John C. Lindon
  • Publisher : Academic Press
  • Release : 11 February 2016
GET THIS BOOKMetabolic Phenotyping in Personalized and Public Healthcare

Metabolic Phenotyping in Personalized and Public Healthcare provides information on the widespread recognition that a personalized or stratified approach to patient treatment may offer a more efficient and effective healthcare solution than phenotype-led approaches. In order to achieve that objective, a deep personal description is required at the level of the genome, proteome, metabolome, or preferably a combination of these aided by technology. This book, edited and written by the outstanding luminaries of this evolving field, evaluates metabolic profiling and

Concepts and Principles of Pharmacology

Concepts and Principles of Pharmacology
  • Author : James E. Barrett,Clive P. Page,Martin C. Michel
  • Publisher : Springer Nature
  • Release : 24 December 2019
GET THIS BOOKConcepts and Principles of Pharmacology

Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

Encyclopedia of Analytical Science

Encyclopedia of Analytical Science
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 02 April 2019
GET THIS BOOKEncyclopedia of Analytical Science

The third edition of the Encyclopedia of Analytical Science is a definitive collection of articles covering the latest technologies in application areas such as medicine, environmental science, food science and geology. Meticulously organized, clearly written and fully interdisciplinary, the Encyclopedia of Analytical Science provides foundational knowledge across the scope of modern analytical chemistry, linking fundamental topics with the latest methodologies. Articles will cover three broad areas: analytical techniques (e.g., mass spectrometry, liquid chromatography, atomic spectrometry); areas of application (e.

Liquid Chromatography

Liquid Chromatography
  • Author : Salvatore Fanali,Paul R. Haddad,Colin Poole,Marja-Liisa Riekkola
  • Publisher : Elsevier
  • Release : 23 June 2017
GET THIS BOOKLiquid Chromatography

Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation,

Precision Medicine for Investigators, Practitioners and Providers

Precision Medicine for Investigators, Practitioners and Providers
  • Author : Joel Faintuch,Salomao Faintuch
  • Publisher : Academic Press
  • Release : 16 November 2019
GET THIS BOOKPrecision Medicine for Investigators, Practitioners and Providers

Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number

10 Years of Pharmacogenetics and Pharmacogenomics

10 Years of Pharmacogenetics and Pharmacogenomics
  • Author : Jose Agundez
  • Publisher : Frontiers Media SA
  • Release : 08 July 2020
GET THIS BOOK10 Years of Pharmacogenetics and Pharmacogenomics

The Specialty Section “Pharmacogenetics and Pharmacogenomics” makes part of two different Journals: Frontiers in Pharmacology and Frontiers in Genetics. This Specialty Section focuses on the mechanisms by which genetic variations influence drug effects and adverse drug events, and cover basic research, clinical translation, applications in drug development and regulatory issues related to this field. Also, studies addressing the role of other factors such as epigenetics, phenotypic factors or drug-drug interactions on drug pharmacokinetics or pharmacodynamics are welcome. The editorial board

Surgical Metabolism

Surgical Metabolism
  • Author : Kimberly A. Davis,Stanley H. Rosenbaum
  • Publisher : Springer Nature
  • Release : 15 April 2020
GET THIS BOOKSurgical Metabolism

The goal of this book is not to follow a traditional systems or organ-based approach but rather to encourage our readers to think of the patients as complex biochemical systems. The book provides information that supplements the more traditional approaches and provides a detailed overview of the metabolic knowledge needed for surgical practice. The text reviews normal physiology, the pathophysiology of starvation and surgical stressors. It also focuses on appropriate nutritional repletion for various common disease states. Specifically, chapters address

Biomarkers of Kidney Disease

Biomarkers of Kidney Disease
  • Author : Charles L. Edelstein
  • Publisher : Academic Press
  • Release : 08 November 2016
GET THIS BOOKBiomarkers of Kidney Disease

Biomarkers of Kidney Disease, Second Edition, focuses on the basic and clinical research of biomarkers in common kidney diseases, detailing the characteristics of an ideal biomarker. The latest techniques for biomarker detection, including metabolomics and proteomics are covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical

Epigenetics and Metabolomics

Epigenetics and Metabolomics
  • Author : Paban K. Agrawala,Poonam Rana
  • Publisher : Elsevier
  • Release : 25 August 2021
GET THIS BOOKEpigenetics and Metabolomics

Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer,

Experimental Museology

Experimental Museology
  • Author : Marianne Achiam,Michael Haldrup,Kirsten Drotner
  • Publisher : Routledge
  • Release : 29 June 2021
GET THIS BOOKExperimental Museology

Experimental Museology scrutinizes innovative endeavours to transform museum interactions with the world. Analysing cutting-edge cases from around the globe, the volume demonstrates how museums can design, apply and assess new modes of audience engagement and participation. Written by an interdisciplinary group of researchers and research-led professionals, the book argues that museum transformations must be focused on conceptualizing and documenting the everyday challenges and choices facing museums, especially in relation to wider social, political and economic ramifications. In order to illuminate

The Handbook of Metabolic Phenotyping

The Handbook of Metabolic Phenotyping
  • Author : John C. Lindon,Jeremy K. Nicholson,Elaine Holmes
  • Publisher : Elsevier
  • Release : 04 October 2018
GET THIS BOOKThe Handbook of Metabolic Phenotyping

The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also

The Handbook of Metabonomics and Metabolomics

The Handbook of Metabonomics and Metabolomics
  • Author : John C. Lindon,Jeremy K. Nicholson,Elaine Holmes
  • Publisher : Elsevier
  • Release : 11 August 2011
GET THIS BOOKThe Handbook of Metabonomics and Metabolomics

Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing

Clinical Metabolomics

Clinical Metabolomics
  • Author : Martin Giera
  • Publisher : Unknown Publisher
  • Release : 25 January 2022
GET THIS BOOKClinical Metabolomics

This detailed volume presents a comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. The methodologies explored here form the core of several very promising initiatives evolving around personalized health care and precision medicine, which can be seen as complimentary to the field of clinical chemistry and aid the aforementioned field with novel disease markers and diagnostic patterns. Written for the highly successful Methods in Molecular Biology

Genomic and Precision Medicine

Genomic and Precision Medicine
  • Author : Geoffrey S. Ginsburg,Huntington F Willard
  • Publisher : Academic Press
  • Release : 22 November 2016
GET THIS BOOKGenomic and Precision Medicine

Genomic and Precision Medicine: Translation and Implementation highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care. The book pinpoints the challenges, barriers, and solutions that have been, or are being, brought forward to enable translation of genome based technologies into health care. A variety of infrastructure (data systems and EMRs), policy (regulatory, reimbursement, privacy), and research (comparative effectiveness research, learning health system approaches)

Precision Public Health

Precision Public Health
  • Author : Tarun Weeramanthri,Hugh Dawkins,Gareth Baynam,Matthew Bellgard,Ori Gudes,James Semmens
  • Publisher : Frontiers Media SA
  • Release : 25 June 2018
GET THIS BOOKPrecision Public Health

Precision Public Health is a new and rapidly evolving field, that examines the application of new technologies to public health policy and practice. It draws on a broad range of disciplines including genomics, spatial data, data linkage, epidemiology, health informatics, big data, predictive analytics and communications. The hope is that these new technologies will strengthen preventive health, improve access to health care, and reach disadvantaged populations in all areas of the world. But what are the downsides and what are