MicroRNA in Regenerative Medicine

This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome’s 1048 encoded microRNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational application, they point to the current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA across repair and regeneration, and special coverage of methodologies and interventions as they point towards organ and tissue engineering Multi-colour text layout with 150 colour figures to illustrate important findings Take home messages encapsulate key lessons throughout text Short chapters offer focused discussion and clear ‘voice’

Produk Detail:

  • Author : Chandan K. Sen
  • Publisher : Elsevier
  • Pages : 1288 pages
  • ISBN : 0124058582
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKMicroRNA in Regenerative Medicine

MicroRNA in Regenerative Medicine

MicroRNA in Regenerative Medicine
  • Author : Chandan K. Sen
  • Publisher : Elsevier
  • Release : 26 November 2014
GET THIS BOOKMicroRNA in Regenerative Medicine

This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome’s 1048 encoded microRNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational

Cell Engineering and Regeneration

Cell Engineering and Regeneration
  • Author : Jeffrey M. Gimble,Darja Marolt,Richard Oreffo,Heinz Redl,Susanne Wolbank
  • Publisher : Springer
  • Release : 01 March 2018
GET THIS BOOKCell Engineering and Regeneration

This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection

MicroRNA in Development and in the Progression of Cancer

MicroRNA in Development and in the Progression of Cancer
  • Author : Shree Ram Singh,Pranela Rameshwar
  • Publisher : Springer Science & Business
  • Release : 21 April 2014
GET THIS BOOKMicroRNA in Development and in the Progression of Cancer

miRNAs are a class of endogenous, small non-protein coding RNA molecules (~ 22 nucleotides) which are novel post-transcriptional regulators of gene expression. Since we have hundreds of miRNAs, the major challenge is now to understand their specific biological function. In fact the experimental evidence suggests that signaling pathways could be ideal candidates for miRNA-mediated regulation. Several studies suggest that miRNAs affect the responsiveness of cells to signaling molecules such as WNT, Notch, TGF-β and EGFR. Altered expression of particular miRNAs has been

Principles of Regenerative Medicine

Principles of Regenerative Medicine
  • Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
  • Publisher : Academic Press
  • Release : 16 December 2010
GET THIS BOOKPrinciples of Regenerative Medicine

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure.

Frontiers in Stem Cell and Regenerative Medicine Research: Volume 9

Frontiers in Stem Cell and Regenerative Medicine Research: Volume 9
  • Author : Atta-ur-Rahman ,Shazia Anjum
  • Publisher : Bentham Science Publishers
  • Release : 05 May 2020
GET THIS BOOKFrontiers in Stem Cell and Regenerative Medicine Research: Volume 9

Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer’s disease and retinal disorders, among others, may well be addressed employing stem cell therapies and tissue regeneration techniques. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell

Vascular Tissue Engineering

Vascular Tissue Engineering
  • Author : Feng Zhao,Kam W. Leong
  • Publisher : Humana
  • Release : 01 October 2021
GET THIS BOOKVascular Tissue Engineering

This volume explores the latest techniques used to study the field of tissue engineered vascular grafts (TEVGs). The chapters in this book cover a wide array of topics such as deriving vascular cells from monocytes and induced pluripotent stem cells; engineering vascular grafts using various biomaterials and stem cells, stem cell-derived, or primary vascular cells; biomaterial modification by anticoagulation molecules; vascular bioengineering technologies such as 3D bioprinting; and fabrication of TEVGs with different geometry and multiphase structures. This book also

Exosomes, Stem Cells and MicroRNA

Exosomes, Stem Cells and MicroRNA
  • Author : Karl L. Mettinger,Pranela Rameshwar,Vinod Kumar
  • Publisher : Springer
  • Release : 12 May 2018
GET THIS BOOKExosomes, Stem Cells and MicroRNA

This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well

Hormones, Metabolism and the Benefits of Exercise

Hormones, Metabolism and the Benefits of Exercise
  • Author : Bruce Spiegelman
  • Publisher : Springer
  • Release : 07 March 2018
GET THIS BOOKHormones, Metabolism and the Benefits of Exercise

The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones

Gene Therapy in Reconstructive and Regenerative Surgery

Gene Therapy in Reconstructive and Regenerative Surgery
  • Author : Giorgio Giatsidis
  • Publisher : Springer
  • Release : 02 August 2018
GET THIS BOOKGene Therapy in Reconstructive and Regenerative Surgery

This book offers an updated overview of the most recent research advances in the field, a comparison of established techniques and methods, a discussion on current experimental and translational challenges, and a commentary on potential opportunities and future directions. Dedicated chapters address and review the preclinical and clinical state-of-the-art of gene therapies for the reconstructive and regenerative surgery of skin and wounds, pathological scars, cartilage, tendons, skeletal muscles, and bio-engineered flaps. A brief guide to developing gene therapy clinical trials

Transcriptional and Translational Regulation of Stem Cells

Transcriptional and Translational Regulation of Stem Cells
  • Author : Gary Hime,Helen Abud
  • Publisher : Springer Science & Business Media
  • Release : 22 May 2013
GET THIS BOOKTranscriptional and Translational Regulation of Stem Cells

This volume describes the latest findings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes – achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches to this topic – (1) illustrating the general principles outlined above through a series of

Cellular Dedifferentiation and Regenerative Medicine

Cellular Dedifferentiation and Regenerative Medicine
  • Author : Xiaobing Fu,Andong Zhao,Tian Hu
  • Publisher : Springer
  • Release : 09 February 2018
GET THIS BOOKCellular Dedifferentiation and Regenerative Medicine

This book focuses on the contribution of cell dedifferentiation to the regenerative process in all body systems, as well as its underlying molecular mechanisms and applications. The book is divided into four parts, the first of which addresses the history of cell dedifferentiation and regenerative medicine. In turn, Part II compares three routes by which cells change their phenotype: dedifferentiation, transdifferentiation, and reprogramming. Part III includes an extensive review of cell dedifferentiation events in all nine body systems for lower

Essentials of Noncoding RNA in Neuroscience

Essentials of Noncoding RNA in Neuroscience
  • Author : Davide De Pietri Tonelli
  • Publisher : Academic Press
  • Release : 14 June 2017
GET THIS BOOKEssentials of Noncoding RNA in Neuroscience

Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain focuses on the role of miRNAs in neurogenesis, gliogenesis, neuronal network formation, and the cell biology of forebrain development. The important role miRNAs play in neuronal maturation, neocortex function, and in some neurodevelopmental disorders is discussed, as are the computational challenges and methods used in the identification of miRNA targets. This book is a valuable reference for neuroscientists who wish to better understand the role of miRNAs in

Stem Cells & Regenerative Medicine

Stem Cells & Regenerative Medicine
  • Author : Krishnarao Appasani,Raghu K. Appasani
  • Publisher : Springer Science & Business Media
  • Release : 01 November 2010
GET THIS BOOKStem Cells & Regenerative Medicine

Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both

Regulatory RNAs

Regulatory RNAs
  • Author : Bibekanand Mallick,Zhumur Ghosh
  • Publisher : Springer Science & Business Media
  • Release : 02 February 2012
GET THIS BOOKRegulatory RNAs

Recent progress in high-throughput technologies and genome wide transcriptome studies have lead to a significant scientific milestone of discovering non-coding RNAs (ncRNAs) which spans through a major portion of the genome. These RNAs most often act as riboregulators, and actively participate in the regulation of important cellular functions at the transcriptional and/or post-transcriptional levels rather than simply being an intermediated messenger between DNA and proteins. As the appreciation for the importance of ncRNAs continues to emerge, it is also