Mitochondria in Neurological Disorders

Mitochondria in Neurological Diseases highlights various therapeutic approaches targeting mitochondria in neurological conditions. Focused on diverse neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, depression, and Amyotrophic lateral sclerosis, topics span basic mitochondrial physiology to mitochondrial dynamics and to the altered states of the nervous system. This book is appropriate for anyone interested in learning more about the physiological and pathophysiological functions of mitochondria in the nervous system. Provides up-to-date information on role of mitochondria in nervous system for graduate students and researchers Presents chapters on energy substrate utilization, calcium handling, mitochondria-organelle communication, and cell signaling Discusses recent techniques in understanding mitochondrial functions in the nervous system Emphasizes the role of altered mitochondrial functions in various neurological conditions and their potential treatment strategies for targeting mitochondria Includes chapter references (key articles, books, protocols) for additional detailed study

Produk Detail:

  • Author : Rajat Sandhir
  • Publisher : Academic Press
  • Pages : 500 pages
  • ISBN : 9780128217313
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKMitochondria in Neurological Disorders

Mitochondria in Neurological Disorders

Mitochondria in Neurological Disorders
  • Author : Rajat Sandhir
  • Publisher : Academic Press
  • Release : 15 June 2022
GET THIS BOOKMitochondria in Neurological Disorders

Mitochondria in Neurological Diseases highlights various therapeutic approaches targeting mitochondria in neurological conditions. Focused on diverse neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, depression, and Amyotrophic lateral sclerosis, topics span basic mitochondrial physiology to mitochondrial dynamics and to the altered states of the nervous system. This book is appropriate for anyone interested in learning more about the physiological and pathophysiological functions of mitochondria in the nervous system. Provides up-to-date information on role of mitochondria in nervous system

Mitochondrial Disorders in Neurology

Mitochondrial Disorders in Neurology
  • Author : Anthony H.V. Schapira,S. Dimauro
  • Publisher : Butterworth-Heinemann
  • Release : 22 October 2013
GET THIS BOOKMitochondrial Disorders in Neurology

Mitochondrial Disorders in Neurology provides an overview of mitochondrial diseases. This book discusses the effects of mitochondrial dysfunction based on the relevant biochemistry and molecular genetics. The abnormal muscle and mitochondrial morphology in a variety of clinical presentations from isolated ophthalmoplegia to severe encephalopathy are also elaborated. This text likewise deliberates Leber's hereditary optic neuropathy, neurodegenerative disorders, and respiratory chain defects. Other topics covered include mitochondrial DNA and the genetics of mitochondrial disease; cytochrome oxidase deficiency; use of tissue culture

Mitochondrial Dysfunction in Neurodegenerative Disorders

Mitochondrial Dysfunction in Neurodegenerative Disorders
  • Author : Amy Katherine Reeve,Kim Jennifer Krishnan,Michael R. Duchen,Doug M Turnbull
  • Publisher : Springer Science & Business Media
  • Release : 15 November 2011
GET THIS BOOKMitochondrial Dysfunction in Neurodegenerative Disorders

As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease and multiple sclerosis and the mechanisms which lead from mitochondrial dysfunction to neurodegeneration. Mitochondrial Dysfunction in Neurodegenerative Disorders brings together contributions from leaders in the field internationally on the various ways in

Mitochondria and Brain Disorders

Mitochondria and Brain Disorders
  • Author : Stavros Baloyannis
  • Publisher : BoD – Books on Demand
  • Release : 11 March 2020
GET THIS BOOKMitochondria and Brain Disorders

The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity depend upon mitochondrial energy production and supply. Besides energy production, mitochondria also play a vital role in calcium homeostasis and may induce apoptosis by excitotoxicity. Mitochondrial dysfunction is related to

Mitochondria-dependent Local Caspase Activation and Mitofusin 2-mediated Mitophagy in Neurodegeneration

Mitochondria-dependent Local Caspase Activation and Mitofusin 2-mediated Mitophagy in Neurodegeneration
  • Author : Hao Chen
  • Publisher : Unknown Publisher
  • Release : 22 January 2022
GET THIS BOOKMitochondria-dependent Local Caspase Activation and Mitofusin 2-mediated Mitophagy in Neurodegeneration

Mitochondria are critical regulators of neuronal physiology. They play a pivotal role in energy supply and Ca2+ buffering. Thus, mitochondria can sustain the synapse and neuronal function. In this regard, the mitochondria with an impaired capacity of bioenergetics or Ca2+ buffering will lead to synapse failure and neurodegeneration. Moreover, emerging evidence has shown that damaged mitochondria are also involved in local caspase activation, which coincides with spine pruning and neurodegeneration. However, the impacts of local caspase signaling on spine dynamics

Mitochondria in Health and Disease

Mitochondria in Health and Disease
  • Author : Carolyn D. Berdanier
  • Publisher : CRC Press
  • Release : 09 June 2005
GET THIS BOOKMitochondria in Health and Disease

It was once assumed that mitochondrial diseases were rare and that few people were affected. As knowledge has grown about these organelles and their function, it became clear that mitochondrial malfunction could be linked to several chronic diseases. Diabetes has been associated with DNA mutation and can cause mutation itself. This text discusses findings involving the effects of disease on mitochondrial number, mitogenesis, and the base sequence of mitochondrial DNA. Experts discuss their study of mitochondria and what happens when

Mitochondrial Dynamics and Neurodegeneration

Mitochondrial Dynamics and Neurodegeneration
  • Author : Bingwei Lu
  • Publisher : Springer Science & Business Media
  • Release : 16 May 2011
GET THIS BOOKMitochondrial Dynamics and Neurodegeneration

Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this

The Functions, Disease-Related Dysfunctions, and Therapeutic Targeting of Neuronal Mitochondria

The Functions, Disease-Related Dysfunctions, and Therapeutic Targeting of Neuronal Mitochondria
  • Author : J. Marie Hardwick
  • Publisher : John Wiley & Sons
  • Release : 09 November 2015
GET THIS BOOKThe Functions, Disease-Related Dysfunctions, and Therapeutic Targeting of Neuronal Mitochondria

This book focuses on dysfunctional neuronal mitochondria, their functions, cell pathways, and properties and how they relate to therapeutics and pharmacology. For scientists and researchers in both industry and academia, this book provides detailed discussion, examples, and approaches, to illustrate the potential of mitochondria as therapeutic targets for neuronal diseases. The book is divided into three parts that cover mitochondrial structure and function, mitochondrial dysfunction and its relationship to neuronal disease, and targeting of dysfunctional neuronal mitochondria for drug development

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : G. Jolles,J. M. Stutzmann
  • Publisher : Academic Press
  • Release : 28 November 1994
GET THIS BOOKNeurodegenerative Diseases

Over the last few years, the considerable progress made in biochemistry, virology, molecular biology and genetics has revealed some of the intimate mechanisms of the neurodegenerative diseases. The present volume is an attempt to review the latest data in the field to illuminate new avenues for future research. This volume gathers together chapters and discussions on the etiology and pathogenesis of the neurodegenerative diseases. Apoptosis of programmed cell death as well as other genetic implications are discussed; special attention is

Mitochondrial Dysfunction and Nanotherapeutics

Mitochondrial Dysfunction and Nanotherapeutics
  • Author : Marcos Roberto de Oliveira
  • Publisher : Academic Press
  • Release : 15 July 2021
GET THIS BOOKMitochondrial Dysfunction and Nanotherapeutics

Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Related Strategies in Mitochondrial Medicine provides a comprehensive overview of mitochondrial dysfunction and current strategies for targeting the organelle. Based on the most current research, the editor lined up a team of worldwide experts to cover the most exciting research in the area, considering the impact through the human life span. This book is structured in two parts that provide a good balance of foundational and applied content. Part I deals with an

Mitochondrial Dynamics and Neurodegeneration

Mitochondrial Dynamics and Neurodegeneration
  • Author : Bingwei Lu
  • Publisher : Springer
  • Release : 02 January 2013
GET THIS BOOKMitochondrial Dynamics and Neurodegeneration

Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this

Mitochondrial Mechanisms of Degeneration and Repair in Parkinson's Disease

Mitochondrial Mechanisms of Degeneration and Repair in Parkinson's Disease
  • Author : Lori M. Buhlman
  • Publisher : Springer
  • Release : 13 September 2016
GET THIS BOOKMitochondrial Mechanisms of Degeneration and Repair in Parkinson's Disease

This volume brings together various theories of how aberrations in mitochondrial function and morphology contribute to neurodegeneration in idiopathic and familial forms of Parkinson’s disease. Moreover, it comprehensively reviews the current search for therapies, and proposes how molecules are involved in specific functions as attractive therapeutic targets. It is expected to facilitate critical thought and discussion about the fundamental aspects of neurodegeneration in Parkinson’s disease and foster the development of therapeutic strategies among researchers and graduate students. Theories

Mitochondrial Metabolism

Mitochondrial Metabolism
  • Author : Jalal Pourahmad,Mohsen Rezaei
  • Publisher : Academic Press
  • Release : 28 July 2021
GET THIS BOOKMitochondrial Metabolism

Mitochondrial Metabolism: An Approach for Disease Management covers mitotherapy from three combined perspectives, Pharmacology, Toxicology and Biochemistry. After an introduction from world-renowned experts, the book's chapters cover the balancing role in reduction/oxidation mitochondria play, mitochondria as targets for therapeutics through its metabolism, mitochondrial contributions to the cell death process, mitochondrial response to environmental toxicants, the mitochondrial role in aging, the impact of calorie restrictive diets, new advances in the identification of altered mitochondria associated signaling pathways in carcinogenesis, and