Mucosal Vaccines

This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not all mucosal immunization routes are created equally when it comes to eliciting immune responses in multiple body compartments. This subject and situations when a mucosal route may not be required for vaccine delivery are reviewed here with an emphasis on the sublingual immunization route, which may offer a safer alternative to the nasal route for induction of broadly disseminated immune responses. External host defenses that inhibit entry of microorganisms at mucosal surfaces also pose obstacles to the efficient internalization of mucosally-applied vaccines. Transcutaneous immunization with appropriate adjuvants and permeation enhancers can induce mucosal immune responses and may be advantageous for bypassing these luminal barriers. Other chapters describe strategies for enhancing uptake of mucosal vaccines, for instance through targeted delivery to antigen-sampling M cells, construction of virus-like particles which mimic natural pathogens, addition of mucoadhesives or formulation as nanoparticles. Topics include edible vaccines as well as plant-based production of subunit or particulate vaccines that could be administered by any route. Dry powder vaccines that could be insufflated or directly applied to mucosal surfaces may be particularly ideal for mass vaccination in developing countries. The manufacture, stability and efficacy of powder formulations is comprehensively reviewed. We conclude with chapters on two of the greatest challenges facing mucosal vaccine development: human immunodeficiency virus and bioterrorist agents. This monograph highlights progress and information that should prove invaluable for the development of contemporary vaccines that prevent infection by these and other mucosal pathogens.

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  • Author : Pamela A. Kozlowski
  • Publisher : Springer Science & Business Media
  • Pages : 198 pages
  • ISBN : 3642236936
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKMucosal Vaccines

Mucosal Vaccines

Mucosal Vaccines
  • Author : Hiroshi Kiyono
  • Publisher : Elsevier
  • Release : 23 October 1996
GET THIS BOOKMucosal Vaccines

This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. Provides the latest views

Mucosal Vaccines

Mucosal Vaccines
  • Author : Pamela A. Kozlowski
  • Publisher : Springer Science & Business Media
  • Release : 11 January 2012
GET THIS BOOKMucosal Vaccines

This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not all mucosal immunization routes are created equally when it comes to eliciting immune responses in multiple body compartments. This subject and situations when a mucosal route may not be required for vaccine delivery are reviewed here with an emphasis on the

Mucosal Vaccines

Mucosal Vaccines
  • Author : Pamela A. Kozlowski
  • Publisher : Springer
  • Release : 26 January 2012
GET THIS BOOKMucosal Vaccines

This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not all mucosal immunization routes are created equally when it comes to eliciting immune responses in multiple body compartments. This subject and situations when a mucosal route may not be required for vaccine delivery are reviewed here with an emphasis on the

Mucosal Vaccines

Mucosal Vaccines
  • Author : David W. Pascual
  • Publisher : Academic Press
  • Release : 19 October 2019
GET THIS BOOKMucosal Vaccines

Mucosal Vaccines: Innovation for Preventing Infectious Diseases discusses basic knowledge and discovery in the area of mucosal immunology and its related scientific fields. This completely updated, revised and authoritative treatise covers all aspects of mucosal vaccines, including their development, mechanisms of action, molecular/cellular aspects and practical applications. The book is organized in a unique format with basic, clinical and practical aspects described and discussed. The accumulated knowledge and new discoveries on the development of mucosal vaccines are logically introduced

Defense of Mucosal Surfaces: Pathogenesis, Immunity and Vaccines

Defense of Mucosal Surfaces: Pathogenesis, Immunity and Vaccines
  • Author : Jean-Pierre Kraehenbuhl,Marian R. Neutra
  • Publisher : Springer
  • Release : 13 December 2011
GET THIS BOOKDefense of Mucosal Surfaces: Pathogenesis, Immunity and Vaccines

Mucosal immunity encompasses a broad field of research that includes areas of epithelial cell and molecular biology, molecular and cellular immunology, microbiology, virology, and vaccinology. This volume presents up to date and concise discussions of concepts as well as recent advances. It provides an overview of the components of the mucosal immune system, and the basic science relevant to mucosal vaccination. The authors assess current research in critical areas including: Organization of mucosal lymphoid tissue; antigen sampling and presentation in

Gram-Positive Bacteria

Gram-Positive Bacteria
  • Author : Gianni Pozzi,Jeremy M. Wells
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOKGram-Positive Bacteria

This book gives a very timely account of recent - partly unpublished - research on the development of gram-positive bacteria as vaccine delivery vehicles for mucosal immunization. The practical and theoretical considerations are discussed and the basic concepts behind the different approaches are compared by giving specific examples of the use of different non-pathogenic bacteria as vaccine vehicles. Thus, a common framework of concepts for a new generation of mucosal vaccines is provided.

Mucosal Health in Aquaculture

Mucosal Health in Aquaculture
  • Author : Benjamin H. Beck,Eric Peatman
  • Publisher : Academic Press
  • Release : 17 February 2015
GET THIS BOOKMucosal Health in Aquaculture

Mucosal Health in Aquaculture is an essential reference on mucosal health for the diverse aquaculture community. Rich in explanatory figures and schematics, the book includes important concepts such as structural and cellular composition of mucosal surfaces in fish and shellfish, known functional roles of molecular and cellular actors during pathogen invasion, impacts of nutrition on the mucosal barriers, impacts of chemical treatments on mucosal surfaces, mucosal vaccines and vaccination strategies, and more. The health of cultured aquaculture species is critical

Essentials of Mucosal Immunology

Essentials of Mucosal Immunology
  • Author : Martin F. Kagnoff,Hiroshi Kiyono
  • Publisher : Academic Press
  • Release : 01 August 1996
GET THIS BOOKEssentials of Mucosal Immunology

Essentials of Mucosal Immunology presents basic concepts as well as new and exciting advances in mucosal immunology and inflammation, the development of mucosal vaccines, and the role of the immune system in mucosal disease. Specific chapters highlight novel approaches to the treatment of autoimmune disease, including the use of oral tolerance; approaches to and vectors for new vaccines; and current concepts in mucosal inflammation and its role in inflammatory bowel disease and ulcer disease. Key Features * Contains the most current

Nanovaccines

Nanovaccines
  • Author : Sergio Rosales-Mendoza,Omar González-Ortega
  • Publisher : Springer Nature
  • Release : 07 November 2019
GET THIS BOOKNanovaccines

This book provides a compilation of the current developments in mucosal nanovaccines, which are an attractive approach to fight against infectious and non-communicable diseases. Since nanomaterials possess unique properties; many of them have a positive effect on vaccine efficacy when used as antigen carriers and have been applied in vaccinology with significant advances over the past years. This book addresses the methodologies for mucosal nanovaccines synthesis; based on the following nanomaterials: gold, PLGA, silica, and chitosan nanoparticles; as well as

Handbook of Mucosal Immunology

Handbook of Mucosal Immunology
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 02 December 2012
GET THIS BOOKHandbook of Mucosal Immunology

Researchers have recently made tremendous progress in the area of mucosal immunology, greatly increasing our understanding of the common mucosal immune system, mucosal infections, and oral immunization. However, thisresearch has not previously been made available in a single work. In its large 81/2"x 11"format, Handbook of Mucosal Immunology covers the entire spectrum of mucosal immunity and is organized in two main sections to present the basic biology of the common mucosal immune system and the immune responses of the mucosae.

Immunopotentiators in Modern Vaccines

Immunopotentiators in Modern Vaccines
  • Author : Virgil Schijns,Derek O'Hagan
  • Publisher : Elsevier
  • Release : 19 December 2005
GET THIS BOOKImmunopotentiators in Modern Vaccines

Immunopotentiators in Modern Vaccines provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations. Contributions from leading international authorities in the field Well-illustrated, informative figures present the interactions between immunopotentiators

Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases

Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases
  • Author : Sergio Rosales-Mendoza
  • Publisher : Springer
  • Release : 21 June 2014
GET THIS BOOKGenetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases

Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases: An Integrated View provides an integrated outlook of the disciplines involved in the development of plant-based vaccines as well as an updated compilation of the successful developments in the field. The volume covers immunological aspects of mucosal vaccine design, molecular approaches to attain high levels of the recombinant antigens, the rationale of using bioreactor to expand plant biomass, and pharmaceutical technology approaches that have been applied to the