Neuronal Chloride Transporters in Health and Disease

Neuronal Chloride Transporters in Health and Disease introduces core concepts and recent advances surrounding the physiology and pathophysiology of neuronal chloride transporters, with particular focus on the KCC and NKCC families of proteins. Chloride transporter biology is reviewed, including its role in setting the transmembrane chloride gradient and in chloride transport-independent functions, such as regulating excitatory neurotransmission. Chapters also address post-translational modifications and the trafficking of chloride transporters, protein interaction partners, and the genetic and environmental factors that regulate expression in neurons. This new volume will provide readers with an up-to-date summary on recent advances in neuronal chloride transporter research, with a particular emphasis on key and emerging topics in the field.

Produk Detail:

  • Author : Xin Tang
  • Publisher : Academic Press
  • Pages : 650 pages
  • ISBN : 9780128153185
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKNeuronal Chloride Transporters in Health and Disease

Neuronal Chloride Transporters in Health and Disease

Neuronal Chloride Transporters in Health and Disease
  • Author : Xin Tang
  • Publisher : Academic Press
  • Release : 01 June 2020
GET THIS BOOKNeuronal Chloride Transporters in Health and Disease

Neuronal Chloride Transporters in Health and Disease introduces core concepts and recent advances surrounding the physiology and pathophysiology of neuronal chloride transporters, with particular focus on the KCC and NKCC families of proteins. Chloride transporter biology is reviewed, including its role in setting the transmembrane chloride gradient and in chloride transport-independent functions, such as regulating excitatory neurotransmission. Chapters also address post-translational modifications and the trafficking of chloride transporters, protein interaction partners, and the genetic and environmental factors that regulate expression

Physiology and Pathology of Chloride Transporters and Channels in the Nervous System

Physiology and Pathology of Chloride Transporters and Channels in the Nervous System
  • Author : F. Javier Alvarez-Leefmans,Eric Delpire
  • Publisher : Academic Press
  • Release : 22 August 2009
GET THIS BOOKPhysiology and Pathology of Chloride Transporters and Channels in the Nervous System

The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium across the plasma membrane of most cells. Research carried out during the last couple of decades has led to a dramatic change

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The olivo-cerebellar system
  • Author : Egidio D'Angelo,Elisa Galliano,Chris I De Zeeuw
  • Publisher : Frontiers Media SA
  • Release : 29 April 2016
GET THIS BOOKThe olivo-cerebellar system

During the last decades, investigations on the olivo-cerebellar system have attained a high level of sophistication, which led to redefinitions of several structural and functional properties of neurons, synapses, connections and circuits. Research has expanded and deepened in so many directions and so many theories and models have been proposed that an ensemble review of the matter is now needed. Yet, hot topics remain open and scientific discussion is very lively at several fronts. One major question, here as well

GABA And Glutamate

GABA And Glutamate
  • Author : Janko Samardzic
  • Publisher : BoD – Books on Demand
  • Release : 21 March 2018
GET THIS BOOKGABA And Glutamate

This book collates the contributions of a selected number of neuroscientists that are interested in the molecular, preclinical, and clinical aspects of neurotransmission research. The seven chapters in this book address the latest research/review data related to GABA/glutamate system's organization and function, the structure of receptors, subtypes and their ligands, as well as the translational approach and clinical implications. The book offers readers a rich collection of data regarding current and future applications of GABA and glutamate neurotransmission,

Hormones and Transport Systems

Hormones and Transport Systems
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 26 March 2015
GET THIS BOOKHormones and Transport Systems

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on hormone and transport systems. Expertise

Ion Channels in Health and Sickness

Ion Channels in Health and Sickness
  • Author : Fatima Shad Kaneez
  • Publisher : BoD – Books on Demand
  • Release : 10 October 2018
GET THIS BOOKIon Channels in Health and Sickness

Ion channels are proteins that make pores in the membranes of excitable cells present both in the brain and the body. These cells are not only responsible for converting chemical and mechanical stimuli into the electrical signals but are also liable for monitoring vital functions. All our activities, from the blinking of our eyes to the beating of our heart and all our senses from smell to sight, touch, taste and hearing are regulated by the ion channels. This book

Research Advances in Alzheimer's Disease and Related Disorders

Research Advances in Alzheimer's Disease and Related Disorders
  • Author : Khalid Iqbal,James A. Mortimer,Bengt Winblad,Henry M. Wisniewski
  • Publisher : John Wiley & Son Limited
  • Release : 08 August 1995
GET THIS BOOKResearch Advances in Alzheimer's Disease and Related Disorders

Following a long period of comparative neglect, Alzheimer’s disease has come to be a major focus of scientific research, and in recent years considerable progress has been made towards understanding the basic molecular mechanisms of the disease and toward developing diagnostic and therapeutic strategies. Here, the latest information on Alzheimer’s disease is presented, including topics such as the mechanisms of degeneration of neurons with neurofibrillary tangles, the formation of brain amyloid in Alzheimer’s disease, risk factors, diagnosis

Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System

Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System
  • Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
  • Publisher : National Academies Press
  • Release : 05 July 2011
GET THIS BOOKGlutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System

Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting