Neuroprotection in Alzheimer s Disease

Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics. Comprehensive reference detailing neuroprotection in Alzheimer’s Disease, with details on nerve cell protection and new advances in disease management Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development Edited by one of the leading researchers in Alzheimer’s Disease

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  • Author : Illana Gozes
  • Publisher : Academic Press
  • Pages : 342 pages
  • ISBN : 0128037121
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKNeuroprotection in Alzheimer s Disease

Neuroprotection in Alzheimer's Disease

Neuroprotection in Alzheimer's Disease
  • Author : Illana Gozes
  • Publisher : Academic Press
  • Release : 30 December 2016
GET THIS BOOKNeuroprotection in Alzheimer's Disease

Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is

Neuroprotection in Autism, Schizophrenia and Alzheimer's Disease

Neuroprotection in Autism, Schizophrenia and Alzheimer's Disease
  • Author : Illana Gozes,Joseph Levine
  • Publisher : Academic Press
  • Release : 01 November 2019
GET THIS BOOKNeuroprotection in Autism, Schizophrenia and Alzheimer's Disease

Some shared pathophysiological mechanisms underlie autism, schizophrenia/mood disorders and Alzheimer's disease, i.e. neurodevelopmental disorders, neuropsychiatric diseases and neurodegenerative disorders. With the rapid advancement of molecular genetics including single cell analysis and detailed molecular characteristics, scientists have the opportunity to follow up on novel mechanistic aspects and offer a novel perspective for the treatments. Neuroprotection in Autism, Schizophrenia and Alzheimer's Disease provides an up-to-date overview of basic and clinical studies concerning similarities in the most prevalent brain disorders, shedding

Neuroprotection

Neuroprotection
  • Author : Matilde Otero-Losada,Francisco Capani,Santiago Perez Lloret
  • Publisher : BoD – Books on Demand
  • Release : 26 November 2020
GET THIS BOOKNeuroprotection

Neurological disease affects nearly 25%–30% of the world’s population, exerting enormous financial strain on the healthcare system. Estimated current costs are around $800 annual billion, and this number is expected to increase exponentially as the global population ages. As such, new and alternative neuroprotective strategies are urgently needed. This book examines some of the most promising approaches in neuroprotection as well as discusses current goals and prospects. Organized into three sections, chapters cover such topics as the use of cannabinoids, medicinal

Alzheimer’s Disease

Alzheimer’s Disease
  • Author : Ralph W. Richter,Brigitte Zoeller Richter
  • Publisher : Springer Science & Business Media
  • Release : 10 October 2003
GET THIS BOOKAlzheimer’s Disease

Alzheimer’s disease (AD) is a devastating and dehumanizing illness affecting increasingly large numbers of elderly and even middle-aged persons in a worldwide epidemic. Alzheimer’s Disease: A Physician’s Guide to Practical Management was written by selected clinicians and scientists who represent some of the world’s leading centers of excellence in AD research. The editors are proud and grateful for their profound contributions. This book is particularly designed to assist physicians and other health-care professionals in the evaluation,

Molecular Mechanisms and Therapeutic Strategies in Alzheimer's Disease

Molecular Mechanisms and Therapeutic Strategies in Alzheimer's Disease
  • Author : Veer Gupta,Vivek Gupta
  • Publisher : LAP Lambert Academic Publishing
  • Release : 28 June 2022
GET THIS BOOKMolecular Mechanisms and Therapeutic Strategies in Alzheimer's Disease

This book provides an insight into the mechanism on the role of amino acid stereospecificity based amyloid beta aggregation pattern; non-apoptotic amyloid beta peptide induced DNA nicking and neuro-neutraceutical property of garlic and curcumin derivatives. These findings provide a molecular understanding of the neurodegeneration and neuroprotection in Alzheimers Disease brain. Novel neuroprotective strategies to treat various neurodegenrative disorders are discussed.

Neuroprotective Natural Products

Neuroprotective Natural Products
  • Author : Goutam Brahmachari
  • Publisher : John Wiley & Sons
  • Release : 24 April 2017
GET THIS BOOKNeuroprotective Natural Products

Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today's destructive diseases. To this extent, the authors discuss the most severe neurological disorders in our modern civilization, such as Alzheimer's, Parkinson's and Huntington's disease, as well as ischemic brain stroke and depression. The emerging diversity of active compounds

Neuroprotection in Autism, Schizophrenia and Alzheimer's disease

Neuroprotection in Autism, Schizophrenia and Alzheimer's disease
  • Author : Illana Gozes,Joseph Levine
  • Publisher : Academic Press
  • Release : 16 October 2019
GET THIS BOOKNeuroprotection in Autism, Schizophrenia and Alzheimer's disease

Neuroprotection in Autism, Schizophrenia and Alzheimer's Disease provides an up-to-date overview on recent clinical studies and the similarities discovered in the most prevalent brain disorders. The book's content will help shed light on basic mechanisms and provide new avenues for early diagnosis toward disease prevention and disease modification. It is written for researchers, clinicians and medical physicians in neuroscience, neurology and psychiatry. Sections discuss the shared pathophysiological mechanisms that underlie autism, schizophrenia/mood disorders and Alzheimer’s disease, i.e.

Nicotinic Acetylcholine Receptor Signaling in Neuroprotection

Nicotinic Acetylcholine Receptor Signaling in Neuroprotection
  • Author : Shun Shimohama,Akinori Akaike,Yoshimi Misu
  • Publisher : Unknown Publisher
  • Release : 08 October 2020
GET THIS BOOKNicotinic Acetylcholine Receptor Signaling in Neuroprotection

This open access book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related functions. Neuroprotection mediated by nAChRs in neurodegenerative diseases such as Alzheimer's disease is the major topic of this book. In response to rapidly evolving areas in clinical

Oxidative Stress and Neurodegenerative Disorders

Oxidative Stress and Neurodegenerative Disorders
  • Author : G. Ali Qureshi,S. Hasan Parvez
  • Publisher : Elsevier
  • Release : 22 March 2007
GET THIS BOOKOxidative Stress and Neurodegenerative Disorders

Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage

Nutrition and Cancer Prevention

Nutrition and Cancer Prevention
  • Author : American Institute for Cancer Research
  • Publisher : Springer Science & Business Media
  • Release : 31 July 2001
GET THIS BOOKNutrition and Cancer Prevention

Recent advances have contributed to our understanding of how a plant-based diet confers many health advantages and how substances from plants may be effective in the prevention of specific cancers. The Ninth Annual Research Conference of the American Institute for Cancer Research has focused on the latest developments in several categories of nutrients of wide contemporary interests. The conference sessions included such topics as the effects of soy, green tea, selenium, wine, grapes, and spices in cancer prevention. This conference

Magnesium in the Central Nervous System

Magnesium in the Central Nervous System
  • Author : Robert Vink,Mihai Nechifor
  • Publisher : University of Adelaide Press
  • Release : 28 June 2022
GET THIS BOOKMagnesium in the Central Nervous System

The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the

Drug Design and Discovery in Alzheimer’s Disease

Drug Design and Discovery in Alzheimer’s Disease
  • Author : Atta-ur-Rahman,Muhammad Iqbal Choudhary
  • Publisher : Elsevier
  • Release : 27 June 2015
GET THIS BOOKDrug Design and Discovery in Alzheimer’s Disease

Drug Design and Discovery in Alzheimer’s Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, focuses on key developments in the understanding of the disease at molecular levels, identification and validation of molecular targets, as well as innovative approaches towards drug discovery, development, and delivery.

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : Uday Kishore
  • Publisher : BoD – Books on Demand
  • Release : 15 May 2013
GET THIS BOOKNeurodegenerative Diseases

This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression. In addition, novel approaches to therapeutic interventions have also been presented. It

Alzheimer's Disease

Alzheimer's Disease
  • Author : Jolanta Dorszewska,Wojciech Kozubski
  • Publisher : BoD – Books on Demand
  • Release : 18 July 2018
GET THIS BOOKAlzheimer's Disease

Alzheimer's disease was discovered over 100 years ago and still belongs to incurable neurological diseases; its pharmacotherapy is considered to be ineffective. This book presents contemporary views on the genetic, biochemical, and immunological determinants of this disease. This book also concerns the issue of Alzheimer's disease prevention through lifestyle and physical activity. Moreover, it describes the therapies used in Alzheimer's disease to slow the progression of the disease and delay its onset. Subsequently, the authors discuss experimental and clinical trials used

Astrocyte

Astrocyte
  • Author : Maria Teresa Gentile,Luca Colucci D’Amato
  • Publisher : BoD – Books on Demand
  • Release : 21 March 2018
GET THIS BOOKAstrocyte

A team of authors from prestigious academic schools contributed to draw up a project that would give a detailed account of astrocyte's morphology and physiology, examining thoroughly all the astrocyte's types; giving an accurate description of their morphology, location, function in the brain; and illustrating their physiology and pathology in terms of dealing with neurons through "gliotransmitters," ionic channels, and membrane receptors expression. This book gives an overview of the crucial role of astrocytes in the physiology of the CNS