Neuropsychiatric Disorders and Epigenetics

Neuropsychiatric Disorders and Epigenetics is a comprehensive reference for the epigenetic basis of most common neuropsychiatric disorders. The volume is organized into chapters representing individual neuropsychiatric disorders, from addition to obesity contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of epigenetic mechanisms including DNA modification, histone post-translational modification, chromatin organization and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects of environmental stimuli on epigenetic states is particularly relevant o disease. Recent discoveries in epigenetic research enabled by epic advances in genomic technologies have positioned the field for broad translation to therapeutic interventions for previously unmanageable disorders Neuropsychiatric disorders represent a prime target of epigenetic interventions as they are highly debilitating, often chronic diseases with enormous costs to society. Thus, this volume will help define epigenetics as a key player in neuropsychiatric disorders, highlighting the full spectrum of epigenetic mechanisms underlying such disorders and introducing the vast range of epigenetic therapies under development. Analyzes the effects of environmental stimuli on epigenetic states that correlate with neuropsychiatric disease induction Reviews the epigenetic basis for common neuropsychiatric disorders, thereby guiding translational therapies for clinicians and mechanistic studies for scientists Extensive use of diagrams, illustrations, tables, and graphical abstracts for each section providing rapid assessment

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  • Author : Dag Yasui
  • Publisher : Academic Press
  • Pages : 444 pages
  • ISBN : 0128005270
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKNeuropsychiatric Disorders and Epigenetics

Neuropsychiatric Disorders and Epigenetics

Neuropsychiatric Disorders and Epigenetics
  • Author : Dag Yasui,Jacob Peedicayil,Dennis R. Grayson
  • Publisher : Academic Press
  • Release : 15 November 2016
GET THIS BOOKNeuropsychiatric Disorders and Epigenetics

Neuropsychiatric Disorders and Epigenetics is a comprehensive reference for the epigenetic basis of most common neuropsychiatric disorders. The volume is organized into chapters representing individual neuropsychiatric disorders, from addition to obesity contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of epigenetic mechanisms including DNA modification, histone post-translational modification, chromatin organization and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects

Chromatin Signaling and Neurological Disorders

Chromatin Signaling and Neurological Disorders
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 24 May 2019
GET THIS BOOKChromatin Signaling and Neurological Disorders

Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin

Epigenetics of Stress and Stress Disorders

Epigenetics of Stress and Stress Disorders
  • Author : Nagy Youssef
  • Publisher : Academic Press
  • Release : 25 February 2022
GET THIS BOOKEpigenetics of Stress and Stress Disorders

Epigenetics of Stress and Stress Disorders, Volume 31 in the Translational Epigenetics series, examines the epigenetic mechanisms involved in modifying DNA or gene expression following prolonged stress and/or trauma. Sections introduce both genetic and psychiatric foundations, including modes of epigenetic modification and gene expression that result from stress, as well as the medical knowledge required to understand stress related disorders and resilience. From here, chapters discuss epigenetic research techniques applied in recent studies, including epigenome-wide association studies (EWAS) of PTSD

Pharmacoepigenetics

Pharmacoepigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 15 April 2019
GET THIS BOOKPharmacoepigenetics

Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the

Epigenetics in Psychiatry

Epigenetics in Psychiatry
  • Author : Jacob Peedicayil,Dennis R. Grayson,Dimitri Avramopoulos
  • Publisher : Academic Press
  • Release : 16 August 2021
GET THIS BOOKEpigenetics in Psychiatry

Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent

Epigenetic Biomarkers and Diagnostics

Epigenetic Biomarkers and Diagnostics
  • Author : José Luis García-Giménez
  • Publisher : Academic Press
  • Release : 07 December 2015
GET THIS BOOKEpigenetic Biomarkers and Diagnostics

Epigenetic Biomarkers and Diagnostics comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based technologies to discover and analyze epigenetic biomarkers. The book concludes with an account of DNA methylation, post-translational modifications and noncoding RNAs as the most promising biomarkers for cancer (i.e.

Epigenetic Regulation in the Nervous System

Epigenetic Regulation in the Nervous System
  • Author : J. David Sweatt,Michael J. Meaney,Eric J. Nestler,Schahram Akbarian
  • Publisher : Academic Press
  • Release : 31 December 2012
GET THIS BOOKEpigenetic Regulation in the Nervous System

Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system. Behavioral epigenetics is the study of how environmental factors alter

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : Uday Kishore
  • Publisher : BoD – Books on Demand
  • Release : 15 May 2013
GET THIS BOOKNeurodegenerative Diseases

This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression. In addition, novel approaches to therapeutic interventions have also been presented. It

The Epigenome and Developmental Origins of Health and Disease

The Epigenome and Developmental Origins of Health and Disease
  • Author : Cheryl S Rosenfeld
  • Publisher : Academic Press
  • Release : 10 October 2015
GET THIS BOOKThe Epigenome and Developmental Origins of Health and Disease

The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological

Neuropsychiatric Disorders

Neuropsychiatric Disorders
  • Author : Koho Miyoshi,Yasushi Morimura,Kiyoshi Maeda
  • Publisher : Springer Science & Business Media
  • Release : 09 August 2010
GET THIS BOOKNeuropsychiatric Disorders

Around the world societies are facing growing aging populations with the concomitant increase in neuropsychiatric disorders. Neuropsychiatric disorders are organic brain diseases with psychiatric symptoms, as in Alzheimer’s and Parkinson’s diseases, that cause cognitive impairment, including dementia, amnesic syndrome, and personality–behavioral changes. As a clinical science, neuropsychiatry aims to explore the complex interrelationship between behavior and brain function from a variety of perspectives, including those of psychology, neurology, and psychiatry. This concise and updated monograph comprises the

The Neurobiology of Schizophrenia

The Neurobiology of Schizophrenia
  • Author : Ted Abel,Thomas Nickl-Jockschat
  • Publisher : Academic Press
  • Release : 08 July 2016
GET THIS BOOKThe Neurobiology of Schizophrenia

The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of

Stress: Genetics, Epigenetics and Genomics

Stress: Genetics, Epigenetics and Genomics
  • Author : George Fink
  • Publisher : Academic Press
  • Release : 24 October 2020
GET THIS BOOKStress: Genetics, Epigenetics and Genomics

This fourth volume in the Handbook of Stress series, Stress: Genetics, Epigenetics and Genomics, deals with the influence that genetics, epigenetics, and genomics have on the effects of and responses to stress. Chapters refer to epigenetic mechanisms that involve DNA methylation, histone modification, and/or noncoding RNA-associated gene activation or silencing. There is also coverage of epigenetic mechanisms in stress-related transgenerational transmission of characteristics, and how these may help explain heritability in some complex human diseases. The Handbook of Stress

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry
  • Author : Thomas Lehner,Bruce L. Miller,Matthew W. State
  • Publisher : Academic Press
  • Release : 07 June 2016
GET THIS BOOKGenomics, Circuits, and Pathways in Clinical Neuropsychiatry

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of

Histone Modifications in Therapy

Histone Modifications in Therapy
  • Author : Pedro Castelo-Branco,Carmen Jeronimo
  • Publisher : Academic Press
  • Release : 21 August 2020
GET THIS BOOKHistone Modifications in Therapy

Histone Modifications in Therapy provides an in-depth analysis of the role of histone mechanisms in major diseases and the promise of targeting histone modifications for disease prevention and treatment. Here, researchers, clinicians and students will discover a thorough, evidence-based discussion of the biology of histones, the diseases engaged by aberrant histone modifications, and pathways with therapeutic potential. Expert chapter addresses the role of histone modifications across a variety of disorders, including cancer, neuropsychiatric, neurodegenerative, cardiac, metabolic, infectious, bacterial, autoimmune and