NMR Spectroscopy in Pharmaceutical Analysis

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience Considers international pharmacopoeias, addressing the concern for licensing Features the work of academics and researchers, appealing to a broad readership

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  • Author : Iwona Wawer
  • Publisher : Elsevier
  • Pages : 528 pages
  • ISBN : 008095152X
  • Rating : 5/5 from 1 reviews
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NMR Spectroscopy in Pharmaceutical Analysis

NMR Spectroscopy in Pharmaceutical Analysis
  • Author : Iwona Wawer,Bernd Diehl
  • Publisher : Elsevier
  • Release : 07 July 2017
GET THIS BOOKNMR Spectroscopy in Pharmaceutical Analysis

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international

NMR in Pharmaceutical Science

NMR in Pharmaceutical Science
  • Author : Robin K. Harris
  • Publisher : John Wiley & Sons
  • Release : 28 September 2015
GET THIS BOOKNMR in Pharmaceutical Science

NMR in Pharmaceutical Sciences is intended to be a comprehensive source of information for the many individuals that utilize MR in studies of relevance to the pharmaceutical sector. The book is intended to educate and inform those who develop and apply MR approaches within the wider pharmaceutical environment, emphasizing the toolbox that is available to spectroscopists and radiologists. This book is structured on the key processes in drug discovery, development and manufacture, but underpinned by an understanding of fundamental NMR

Annual Reports on NMR Spectroscopy

Annual Reports on NMR Spectroscopy
  • Author : Graham A. Webb
  • Publisher : Academic Press
  • Release : 27 September 2013
GET THIS BOOKAnnual Reports on NMR Spectroscopy

Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has gained such significance as NMR spectroscopy. It is used in all branches of science in which precise structural determination is required and in which the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and non-specialist

Handbook of Modern Pharmaceutical Analysis

Handbook of Modern Pharmaceutical Analysis
  • Author : Satinder Ahuja,Stephen Scypinski
  • Publisher : Academic Press
  • Release : 11 November 2010
GET THIS BOOKHandbook of Modern Pharmaceutical Analysis

Handbook of Modern Pharmaceutical Analysis, Second Edition, synthesizes the complex research and recent changes in the field, while covering the techniques and technology required for today's laboratories. The work integrates strategy, case studies, methodologies, and implications of new regulatory structures, providing complete coverage of quality assurance from the point of discovery to the point of use. Treats pharmaceutical analysis (PA) as an integral partner to the drug development process rather than as a service to it Covers method development, validation,

Pharmaceutical Excipients

Pharmaceutical Excipients
  • Author : David E. Bugay,W. Paul Findlay
  • Publisher : CRC Press
  • Release : 23 February 1999
GET THIS BOOKPharmaceutical Excipients

Meeting the need for a hands-on guide elucidating the role of molecular spectroscopy in the physical characterization of pharmaceutical solids, two experts from the industry gather theoretical discussions of infrared, Raman, and nuclear magnetic resonance spectroscopy. They provide recommendations on spectral data acquisition techniques and include 600 spectra for 300 of the most commonly used excipients. Complete with references, equations, tables, and a CAS registry number index, the book covers the drug development process, including chemical identification of substances, investigative studies, competitor

Applications of NMR Spectroscopy:

Applications of NMR Spectroscopy:
  • Author : Atta-ur-Rahman,M. Iqbal Choudhary
  • Publisher : Elsevier
  • Release : 10 December 2015
GET THIS BOOKApplications of NMR Spectroscopy:

Applications of NMR Spectroscopy, Volume 2, originally published by Bentham and now distributed by Elsevier, presents the latest developments in the field of NMR spectroscopy, including the analysis of plant polyphenols, the role of NMR spectroscopy in neuroradiology, NMR-based sensors, studies on protein and nucleic acid structure and function, and mathematical formations for NMR spectroscopy in structural biology. The fully illustrated chapters contain comprehensive references to the recent literature. The applications presented cover a wide range of the field, such as

Essentials of Pharmaceutical Analysis

Essentials of Pharmaceutical Analysis
  • Author : Muhammad Sajid Hamid Akash,Kanwal Rehman
  • Publisher : Springer Nature
  • Release : 17 December 2019
GET THIS BOOKEssentials of Pharmaceutical Analysis

Recent advances in the pharmaceutical sciences and biotechnology have facilitated the production, design, formulation and use of various types of pharmaceuticals and biopharmaceuticals. This book provides detailed information on the background, basic principles, and components of techniques used for the analysis of pharmaceuticals and biopharmaceuticals. Focusing on those analytical techniques that are most frequently used for pharmaceuticals, it classifies them into three major sections and 19 chapters, each of which discusses a respective technique in detail. Chiefly intended for graduate students

New Applications of NMR in Drug Discovery and Development

New Applications of NMR in Drug Discovery and Development
  • Author : Leoncio Garrido,Nicolau Beckmann,William Price
  • Publisher : Royal Society of Chemistry
  • Release : 24 July 2013
GET THIS BOOKNew Applications of NMR in Drug Discovery and Development

This book presents a review of new developments in NMR for applications in medicinal chemistry and drug discovery. The contents will focus on consolidated and emerging techniques and methods that are at present not widely applied, however it is considered that they could contribute to the advancement of drug discovery and drug development.

Pharmaceutical Drug Analysis

Pharmaceutical Drug Analysis
  • Author : Ashutosh Kar
  • Publisher : New Age International
  • Release : 01 December 2005
GET THIS BOOKPharmaceutical Drug Analysis

About the Book: During the past two decades, there have been magnificent and significant advances in both analytical instrumentation and computerized data handling devices across the globe. In this specific context the remarkable proliferation of windows

Pharmaceutical Analysis

Pharmaceutical Analysis
  • Author : David C Lee,Michael L. Webb
  • Publisher : John Wiley & Sons
  • Release : 12 February 2009
GET THIS BOOKPharmaceutical Analysis

The use of analytical sciences in the discovery, development andmanufacture of pharmaceuticals is wide-ranging. From the analysisof minute amounts of complex biological materials to the qualitycontrol of the final dosage form, the use of analytical technologycovers an immense range of techniques and disciplines. This book concentrates on the analytical aspects of drugdevelopment and manufacture, focusing on the analysis of the activeingredient or drug substance. It provides those joining theindustry or other areas of pharmaceutical research with a source ofreference to

Nuclear Magnetic Resonance

Nuclear Magnetic Resonance
  • Author : G. A. Webb,Krystyna Kamienska-Trela
  • Publisher : Royal Society of Chemistry
  • Release : 01 March 2010
GET THIS BOOKNuclear Magnetic Resonance

As a spectroscopic method, nuclear magnetic resonance (NMR) has seen spectacular growth, both as a technique and in its applications. Today's applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive coverage of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular

Spectroscopic Analyses

Spectroscopic Analyses
  • Author : Eram Sharmin,Fahmina Zafar
  • Publisher : BoD – Books on Demand
  • Release : 06 December 2017
GET THIS BOOKSpectroscopic Analyses

The book presents developments and applications of these methods, such as NMR, mass, and others, including their applications in pharmaceutical and biomedical analyses. The book is divided into two sections. The first section covers spectroscopic methods, their applications, and their significance as characterization tools; the second section is dedicated to the applications of spectrophotometric methods in pharmaceutical and biomedical analyses. This book would be useful for students, scholars, and scientists engaged in synthesis, analyses, and applications of materials/polymers.

Structure-activity Relationship Studies in Drug Development by NMR Spectroscopy

Structure-activity Relationship Studies in Drug Development by NMR Spectroscopy
  • Author : Atta-ur- Rahman,M. Iqbal Choudhary
  • Publisher : Bentham Science Publishers
  • Release : 03 July 2022
GET THIS BOOKStructure-activity Relationship Studies in Drug Development by NMR Spectroscopy

"NMR (Nuclear Magnetic Resonance) Spectroscopy has found significant applications in drug discovery based on its capacity to map molecular interactions at the atomic level. Chemical shifts, cross relaxation, and exchange of protons are among the NMR parame"

Pharmaceutical Analysis E-Book

Pharmaceutical Analysis E-Book
  • Author : David G. Watson
  • Publisher : Elsevier Health Sciences
  • Release : 24 December 2015
GET THIS BOOKPharmaceutical Analysis E-Book

Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of chemical, physical and microbiological analyses. It is reckoned that over £10 billion is spent annually in the UK alone on pharmaceutical analysis, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and

Applications of NMR Spectroscopy:

Applications of NMR Spectroscopy:
  • Author : Atta-ur-Rahman,M. Iqbal Choudhary
  • Publisher : Elsevier
  • Release : 11 December 2015
GET THIS BOOKApplications of NMR Spectroscopy:

Applications of NMR Spectroscopy, Volume 1, originally published by Bentham and now distributed by Elsevier, presents the latest developments in the field of NMR spectroscopy, including the analysis of edible oils and lipid content in foods, the role of NMR spectroscopy in the human metabolomics and the diagnosis of autism-related disorders, protein-protein interactions, and NMR spectroscopy of chiral molecules. The fully illustrated chapters contain comprehensive references to the recent literature. The applications presented cover a wide range of the field, such