Spherical Nucleic Acids

Spherical nucleic acids (SNAs) comprise a nanoparticle core and a densely packed and highly oriented nucleic acid shell, typically DNA or RNA. They have novel architecture-dependent properties that distinguish them from all other forms of nucleic acids and make them useful in materials synthesis, catalysis, diagnostics, therapeutics, and optics/plasmonics. This book covers over two decades of Dr. Mirkin’s research on SNAs and their anisotropic analogues, including synthesis and fundamental properties, and applications in colloidal crystallization, adaptive matter, and nanomedicine, spanning extra- and intracellular diagnostics, gene regulation, and immunomodulation. It is a reprint volume that compiles 101 key papers from high-impact journals in this research area published by the Mirkin Group at Northwestern University, Illinois, USA, within the International Institute for Nanotechnology, and collaborators. Volume 1 provides an overview and a historical framework of engineering matter from DNA-modified constructs and discusses the enabling features of nucleic acid–functionalized nanomaterials. Volume 2 covers design rules for colloidal crystallization, building blocks for crystal engineering, and DNA and RNA as programmable bonds. Volume 3 discusses colloidal crystallization processes and routes to hierarchical assembly, dynamic nanoparticle superlattices, surface-based and template-confined colloidal crystallization, optics and plasmonics with nanoparticle superlattices, and postsynthetic modification and catalysis with nanoparticle superlattices. Volume 4 covers diagnostic modalities, and intracellular therapeutic and diagnostic schemes based upon nucleic acid–functionalized nanomaterials.

Produk Detail:

  • Author : Chad A. Mirkin
  • Publisher : CRC Press
  • Pages : 1806 pages
  • ISBN : 0429578067
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKSpherical Nucleic Acids

Spherical Nucleic Acids

Spherical Nucleic Acids
  • Author : Chad A. Mirkin
  • Publisher : CRC Press
  • Release : 01 September 2020
GET THIS BOOKSpherical Nucleic Acids

Spherical nucleic acids (SNAs) comprise a nanoparticle core and a densely packed and highly oriented nucleic acid shell, typically DNA or RNA. They have novel architecture-dependent properties that distinguish them from all other forms of nucleic acids and make them useful in materials synthesis, catalysis, diagnostics, therapeutics, and optics/plasmonics. This book covers over two decades of Dr. Mirkin’s research on SNAs and their anisotropic analogues, including synthesis and fundamental properties, and applications in colloidal crystallization, adaptive matter, and

Principles of Nucleic Acid Structure

Principles of Nucleic Acid Structure
  • Author : Stephen Neidle
  • Publisher : Elsevier
  • Release : 26 July 2010
GET THIS BOOKPrinciples of Nucleic Acid Structure

This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, Principles of Nucleic Acid Structure includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features

Visualization of Nucleic Acids

Visualization of Nucleic Acids
  • Author : Gerard Morel
  • Publisher : CRC Press
  • Release : 30 March 1995
GET THIS BOOKVisualization of Nucleic Acids

This book presents a review of the principle approaches for visualizing DNA and RNA. Using scanning tunneling and atomic force microscopes, the three-dimensional image of the surface of nucleic acids can be seen at atomic-scale resolutions. Spreading methods provide useful details on structural features of isolated molecules, but the major constituent of living matter is water, and the cryomicroscope makes it possible to look at DNA in its aqueous environment. Genes can be detected simultaneously in situ in chromosomes using

Nucleic Acids and Proteins in Soil

Nucleic Acids and Proteins in Soil
  • Author : Paolo Nannipieri,Kornelia Smalla
  • Publisher : Springer Science & Business Media
  • Release : 22 September 2006
GET THIS BOOKNucleic Acids and Proteins in Soil

With millions of different bacterial species living in soil, the microbial community is extremely complex, varying at very small scales. Microbe-driven functions are essential for most processes in soil. Thus, a better understanding of this microbial diversity will be invaluable for the management of the various soil functions. Nucleic Acids and Proteins in Soil combines traditional approaches in soil microbiology and biochemistry with the latest techniques in molecular microbial ecology. Included are methods to analyse the presence and importance of

Nucleic Acids in Chemistry and Biology

Nucleic Acids in Chemistry and Biology
  • Author : G. Michael Blackburn
  • Publisher : Royal Society of Chemistry
  • Release : 01 January 2006
GET THIS BOOKNucleic Acids in Chemistry and Biology

The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved. Revised and updated Nucleic Acids in Chemistry and Biology 3rd Edition discusses in detail, both the chemistry and biology of nucleic acids and brings RNA into parity with DNA. Written by leading experts, with extensive teaching experience, this new edition provides some updated and expanded coverage of nucleic acid chemistry, reactions and interactions with proteins and

Nucleic Acids and Molecular Biology

Nucleic Acids and Molecular Biology
  • Author : Fritz Eckstein,David M. J. Lilley
  • Publisher : Springer
  • Release : 10 January 2012
GET THIS BOOKNucleic Acids and Molecular Biology

A wide range of topics are covered, including articles on nucleic acid structure, through their interactions with proteins to the control of gene expression. A number of authors address the subject of RNA, including the difficult but important subject of its chemical synthesis, the complexities of its structures and the mechanisms of transcript splicing. The probing of DNA structure is reviewed in papers on the application of hydroxyl radical and 1,10 phenanthroline copper cleavages. A number of important DNA-protein interactions are

Nucleic Acids and Molecular Biology

Nucleic Acids and Molecular Biology
  • Author : Fritz Eckstein,David M. J. Lilley
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKNucleic Acids and Molecular Biology

A wide range of topics are covered, including articles on nucleic acid structure, through their interactions with proteins to the control of gene expression. A number of authors address the subject of RNA, including the difficult but important subject of its chemical synthesis, the complexities of its structures and the mechanisms of transcript splicing. The probing of DNA structure is reviewed in papers on the application of hydroxyl radical and 1,10 phenanthroline copper cleavages. A number of important DNA-protein interactions are

Nucleic Acids in Immunology

Nucleic Acids in Immunology
  • Author : O. J. Plescia,W. Braun
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKNucleic Acids in Immunology

Two fields have played a leading role in biomedical research in recent years, the biochemistry of nucleic acids and immunology. Yet, with the exception of those aspects which have been concerned with antibody synthesis as an example of protein synthesis, there was until recently a lack of direct association between the two fields. Until quite recently the antigenicity of nucleic acids was still in doubt and indeed represented a controversial subject. Also, the exact role of the various nucleic acids

Organic Chemistry of Nucleic Acids

Organic Chemistry of Nucleic Acids
  • Author : N. Kochetkov
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKOrganic Chemistry of Nucleic Acids

The study of nucleic acids is one of the most rapidly developing fields in modern science. The exceptionally important role of the nucleic acids as a key to the understanding of the nature of life is reflected in the enormous number of published works on the subject, including many outstanding monographs and surveys. The pathways of syn thesis and metabolism of nucleic acid,s and the many and varied biological functions of these biopolymers are examined with the utmost detail

Modified Nucleic Acids

Modified Nucleic Acids
  • Author : Kazuhiko Nakatani,Yitzhak Tor
  • Publisher : Springer
  • Release : 04 April 2016
GET THIS BOOKModified Nucleic Acids

This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book

Electrochemistry of Nucleic Acids and Proteins

Electrochemistry of Nucleic Acids and Proteins
  • Author : Emil Paleček,Frieder Scheller,Joseph Wang
  • Publisher : Elsevier
  • Release : 21 June 2021
GET THIS BOOKElectrochemistry of Nucleic Acids and Proteins

DNA (sometimes referred to as the molecule of life), is the most interesting and most important of all molecules. Electrochemistry of Nucleic Acids and Proteins: Towards Electrochemical Sensors for Genomics and Proteomics is devoted to the electrochemistry of DNA and RNA and to the development of sensors for detecting DNA damage and DNA hybridization. Volume 1, in the brand new series Perspectives in Bioanalysis, looks at the electroanalytical chemistry of nucleic acids and proteins, development of electrochemical sensors and their application

Advanced Organic Chemistry of Nucleic Acids

Advanced Organic Chemistry of Nucleic Acids
  • Author : Zoe A. Shabarova,Alexey A. Bogdanov
  • Publisher : John Wiley & Sons
  • Release : 11 July 2008
GET THIS BOOKAdvanced Organic Chemistry of Nucleic Acids

Sequencing, cloning, transcription - these are but a few key techniques behind the current breathtaking advances in molecular biology and biochemistry. As these methods continuosly diversify, biochemists need a sound chemical understanding to keep the pace. Chemists beginning working in the molecular biology lab need an introduction to this field from their point of view. This book serves both: it describes most of the known chemical reactions of nucleosides, nucleotides, and nucleic acids in sufficient detail to provide the desired

Nucleic Acids

Nucleic Acids
  • Author : John M. Walker
  • Publisher : Humana Press
  • Release : 11 December 1984
GET THIS BOOKNucleic Acids

In recent years there has been a tremendous increase in our understanding of the functioning of the cell at the molecular level. This has been achieved in the main by the invention and development of new methodology, parti- larly in that area generally referred to as "genetic en- neering". While this revolution has been taking place in the field of nucleic acids research, the protein chemist has at the same time developed fresh methodology to keep pace with the requirements

Nucleic Acids and Proteins in Plants I

Nucleic Acids and Proteins in Plants I
  • Author : D. Boulter
  • Publisher : Springer
  • Release : 18 November 2011
GET THIS BOOKNucleic Acids and Proteins in Plants I

D. BOULTER and B. PARTHIER At the time of the former edition of the Encyclopedia of Plant Physiology, approximately 25 years ago, no complete plant protein amino acid sequences or nucleic acid sequences had been determined. Although the structure of DNA and its function as the genetic material had just been reported, little detail was known of the mechanism of its action, and D. G. CATCHSIDE was to write in the first chapter of the first volume of the Encyclopedia: "There

Handbook of Biochemistry

Handbook of Biochemistry
  • Author : Gerald D Fasman
  • Publisher : CRC Press
  • Release : 08 August 2019
GET THIS BOOKHandbook of Biochemistry

This volume contains information on the nucleotide composition of bacterial DNA. Eukaryotic protists, etc.; Nearest neighbour frequencies in DNA; repeated and unique sequences in eukaryotes; nucleic acid sequences in bacteriophage, chloroplasts, mitochondria, kinetoplasts, satellites and TRNA. Information on the physical properties of RNA, atomic coordinates of DNA-DNA. Also included in this volume is information on enzymes involved in nucleic acid function.