Ocular Transporters and Receptors

Ocular transporters and receptors contains detailed descriptions of major transporters and receptors expressed in the eye, with special emphasis on their role in drug delivery. The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to successful drug delivery to the eye. Hence ocular transporters and receptors are important targets for drug delivery. A significant advancement has been made in the field of ocular transport research and their role in drug delivery. In this book the cutting edge research being carried out in this field is compiled and summarized. The book focuses on key areas, including the anatomy and physiology of the eye, biology of ocular transporters and receptors, techniques in characterization of transporters and receptors, transporters and receptors in the anterior and posterior segment in the eye, the role of ocular transporters and receptors in drug delivery, and transporter-metabolism interplay in the eye. Highly focused on ocular transporters Most up-to-date research compilation Detailed description of role of transporters and receptors in ocular drug discovery and delivery

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  • Author : Ashim K Mitra
  • Publisher : Elsevier
  • Pages : 276 pages
  • ISBN : 190881831X
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKOcular Transporters and Receptors

Ocular Transporters and Receptors

Ocular Transporters and Receptors
  • Author : Ashim K Mitra
  • Publisher : Elsevier
  • Release : 31 October 2013
GET THIS BOOKOcular Transporters and Receptors

Ocular transporters and receptors contains detailed descriptions of major transporters and receptors expressed in the eye, with special emphasis on their role in drug delivery. The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to successful drug delivery to the eye. Hence ocular transporters and receptors are important targets for drug delivery. A significant advancement has been made in the field of ocular transport research and their role in drug delivery. In this

Ocular Transporters in Ophthalmic Diseases and Drug Delivery

Ocular Transporters in Ophthalmic Diseases and Drug Delivery
  • Author : Joyce Tombran-Tink,Colin J. Barnstable
  • Publisher : Springer Science & Business Media
  • Release : 09 April 2008
GET THIS BOOKOcular Transporters in Ophthalmic Diseases and Drug Delivery

In this exceptionally important new work, a panel of distinguished authors discusses all the latest developments in the study of ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium and nutrients across the retinal pigment epithelium.

Mechanisms of Water and Solute Transport at the Ocular Surface

Mechanisms of Water and Solute Transport at the Ocular Surface
  • Author : Marc Harris Levin
  • Publisher : Unknown Publisher
  • Release : 21 June 2021
GET THIS BOOKMechanisms of Water and Solute Transport at the Ocular Surface

Actions of and interactions among AQPs, CFTR, and ENaC are also of central importance to airway surface liquid (ASL) function and dysfunction, and have been considered with regard to both the etiology and possible treatment of cystic fibrosis (CF) lung disease. Recent data indicated clinical benefit of nebulized hypertonic saline in CF. The proposed mechanism of increased ASL volume relies on purported inhibition of lung AQPs by the ENaC inhibitor amiloride. Sensitive fluorescence methods indicated that amiloride does not inhibit

Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3

Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3
  • Author : David A. Sullivan,Michael E. Stern,Kazuo Tsubota,Darlene A. Dartt,Rose M. Sullivan,B. Britt Bromberg
  • Publisher : Springer
  • Release : 31 January 2003
GET THIS BOOKLacrimal Gland, Tear Film, and Dry Eye Syndromes 3

During the past several decades, a significant international research effort has been directed towards understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays a critical role in maintaining corneal and conjunctival integrity, protecting against microbial challenge and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in numerous individuals throughout the world, may

Drug Transporters in Drug Disposition, Effects and Toxicity

Drug Transporters in Drug Disposition, Effects and Toxicity
  • Author : Xiaodong Liu,Guoyu Pan
  • Publisher : Springer Nature
  • Release : 30 September 2019
GET THIS BOOKDrug Transporters in Drug Disposition, Effects and Toxicity

This book provides with a comprehensive overview of the role of drug transporters in drug disposition and efficacy/toxicity, as well as drug-drug interactions and recent advances in the field. Transporters are known determinants of drug disposition and efficacy/toxicity. In general, they are divided into solute carrier (SLC) and ATP binding cassette (ABC) families, and are located along cell membranes, where they mediate drug uptake into cells and export out of cells. Drug transporters are essential in maintaining cell

Drug Delivery

Drug Delivery
  • Author : Ashim K. Mitra,Chairman and Curator's Professor Pharmaceutical Sciences University of Missouri Kansas City Missouri Ashim K Mitra,Deep Kwatra,Aswani Dutt Vadlapudi
  • Publisher : Jones & Bartlett Publishers
  • Release : 18 August 2014
GET THIS BOOKDrug Delivery

Drug Delivery is the latest and most up-to-date text on drug delivery and offers an excellent working foundation for students and clinicians in health professions and graduate students including nursing, pharmacy, medicine, dentistry, as well as researchers and scientists. Presenting this complex content in an organized and concise format, Drug Delivery allows students to gain a strong understanding of the key concepts of drug delivery.This text focuses on the basic concepts of drug delivery while thoroughly examining various topics