ODE PDE synuclein Models for Parkinson s Disease

ODE/PDE Alpha-Synuclein Models for Parkinson’s Disease discusses a mechanism for the evolution of Parkinson’s Disease (PD) based on the dynamics of the protein α-synuclein, a monomer that has been implicated in this disease. Specifically, α-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the α-synuclein monomer and polymer, and then details the methodology for the numerical integration of ODE/PDE systems which can be applied to computer-based analyses of alternative models based on the reader's interest. This book facilitates immediate computer use for research without the necessity to first learn the basic concepts of numerical analysis for ODE/PDEs and programming algorithms Includes PDE routines based on the method of lines (MOL) for computer-based implementation of ODE/PDE models Offers transportable computer source codes for readers, with line-by-line code descriptions relating to the mathematical model and algorithms Authored by a leading researcher and educator in ODE/PDE models

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  • Author : William E. Schiesser
  • Publisher : Academic Press
  • Pages : 228 pages
  • ISBN : 0128148020
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKODE PDE synuclein Models for Parkinson s Disease

ODE/PDE α-synuclein Models for Parkinson’s Disease

ODE/PDE α-synuclein Models for Parkinson’s Disease
  • Author : William E. Schiesser
  • Publisher : Academic Press
  • Release : 13 February 2018
GET THIS BOOKODE/PDE α-synuclein Models for Parkinson’s Disease

ODE/PDE Alpha-Synuclein Models for Parkinson’s Disease discusses a mechanism for the evolution of Parkinson’s Disease (PD) based on the dynamics of the protein α-synuclein, a monomer that has been implicated in this disease. Specifically, α-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the α-synuclein monomer and polymer, and then details the

ODE / PDE Alpha-Synuclein Models for Parkinson's Disease

ODE / PDE Alpha-Synuclein Models for Parkinson's Disease
  • Author : William E. Schiesser
  • Publisher : Academic Press
  • Release : 14 February 2018
GET THIS BOOKODE / PDE Alpha-Synuclein Models for Parkinson's Disease

ODE/PDE Alpha-Synuclein Models for Parkinson's Disease discusses a mechanism for the evolution of Parkinson's Disease (PD) based on the dynamics of the protein α-synuclein, a monomer that has been implicated in this disease. Specifically, α-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the α-synuclein monomer and polymer, and then details the methodology for

Network Spread Models of Neurodegenerative Diseases

Network Spread Models of Neurodegenerative Diseases
  • Author : Ashish Raj,Yasser Iturria Medina
  • Publisher : Frontiers Media SA
  • Release : 18 April 2019
GET THIS BOOKNetwork Spread Models of Neurodegenerative Diseases

It is a real pleasure to introduce the excellent papers contributed by leading experts to our Research Topic proposing various network models of dementia spread. The focus is strongly on disease-specific mathematical modeling rather than general graph theory. The emerging field of network neuroscience visualizes the brain as a graph consisting of nodes representing regions and edges as connections between them. This complex network supports efficient communication along neural projections, but also, unfortunately, the transmission and progression of Alzheimer’s

Dynamic Modeling of Transport Process Systems

Dynamic Modeling of Transport Process Systems
  • Author : C. A. Silebi,William E. Schiesser
  • Publisher : Elsevier
  • Release : 02 December 2012
GET THIS BOOKDynamic Modeling of Transport Process Systems

This book presents a methodology for the development and computer implementation of dynamic models for transport process systems. Rather than developing the general equations of transport phenomena, it develops the equations required specifically for each new example application. These equations are generally of two types: ordinary differential equations (ODEs) and partial differential equations (PDEs) for which time is an independent variable. The computer-based methodology presented is general purpose and can be applied to most applications requiring the numerical integration of

Parkinson's Disease

Parkinson's Disease
  • Author : Christopher George Clough,K. Ray Chaudhuri,Kapil D. Sethi
  • Publisher : Health Press (UK)
  • Release : 16 June 2021
GET THIS BOOKParkinson's Disease

Parkinson's disease, first described by James Parkinson in 1817, is one of the most important disabling conditions of later life. It is estimated to affect one per cent of 70-year-olds, but is also seen in younger people, with ten per cent of cases occurring before the age of 50. Proper care of patients with Parkinson's disease requires many different healthcare professionals to work together as a team and research into parkinsonism continues at an ever-increasing pace. Patients need to be reassured that

The Numerical Method of Lines

The Numerical Method of Lines
  • Author : William E. Schiesser
  • Publisher : Elsevier
  • Release : 27 July 2012
GET THIS BOOKThe Numerical Method of Lines

This is the first book on the numerical method of lines, a relatively new method for solving partial differential equations. The Numerical Method of Lines is also the first book to accommodate all major classes of partial differential equations. This is essentially an applications book for computer scientists. The author will separately offer a disk of FORTRAN 77 programs with 250 specific applications, ranging from "Shuttle Launch Simulation" to "Temperature Control of a Nuclear Fuel Rod."

Posttraumatic Stress Disorder and Related Diseases in Combat Veterans

Posttraumatic Stress Disorder and Related Diseases in Combat Veterans
  • Author : Elspeth Cameron Ritchie
  • Publisher : Springer
  • Release : 27 October 2015
GET THIS BOOKPosttraumatic Stress Disorder and Related Diseases in Combat Veterans

This book takes a case-based approach to addressing the challenges psychiatrists and other clinicians face when working with American combat veterans after their return from a war zone. Written by experts, the book concentrates on a wide variety of concerns associated with posttraumatic stress disorder (PTSD), including different treatments of PTSD. The text also looks at PTSD comorbidities, such as depression and traumatic brain injury (TBI) and other conditions masquerading as PTSD. Finally, the authors touch on other subjects concerning

Numerical Integration of Space Fractional Partial Differential Equations

Numerical Integration of Space Fractional Partial Differential Equations
  • Author : Younes Salehi,William E. Schiesser
  • Publisher : Morgan & Claypool Publishers
  • Release : 06 December 2017
GET THIS BOOKNumerical Integration of Space Fractional Partial Differential Equations

Partial differential equations (PDEs) are one of the most used widely forms of mathematics in science and engineering. PDEs can have partial derivatives with respect to (1) an initial value variable, typically time, and (2) boundary value variables, typically spatial variables. Therefore, two fractional PDEs can be considered, (1) fractional in time (TFPDEs), and (2) fractional in space (SFPDEs). The two volumes are directed to the development and use of SFPDEs, with the discussion divided as: •Vol 1: Introduction to Algorithms and Computer Coding in

Bio-nanoimaging

Bio-nanoimaging
  • Author : Vladimir Uversky,Yuri Lyubchenko
  • Publisher : Academic Press
  • Release : 05 November 2013
GET THIS BOOKBio-nanoimaging

Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species. The book is divided into three sections covering: - Nanotechnology and nanoimaging technology, including cryoelectron microscopy of beta(2)-microglobulin, studying amyloidogensis by FRET; and scanning tunneling microscopy of protein deposits - Polymorphisms of protein misfolded and aggregated species, including fibrillar polymorphism, amyloid-like protofibrils, and insulin oligomers - Polymorphisms of misfolding and aggregation processes, including multiple

5th International Conference on Biomedical Engineering in Vietnam

5th International Conference on Biomedical Engineering in Vietnam
  • Author : Vo Van Toi,Tran Ha Lien Phuong
  • Publisher : Springer
  • Release : 18 November 2014
GET THIS BOOK5th International Conference on Biomedical Engineering in Vietnam

This volume presents the proceedings of the Fifth International Conference on the Development of Biomedical Engineering in Vietnam which was held from June 16-18, 2014 in Ho Chi Minh City. The volume reflects the progress of Biomedical Engineering and discusses problems and solutions. I aims identifying new challenges, and shaping future directions for research in biomedical engineering fields including medical instrumentation, bioinformatics, biomechanics, medical imaging, drug delivery therapy, regenerative medicine and entrepreneurship in medical devices.

Amyloid Fibrils and Prefibrillar Aggregates

Amyloid Fibrils and Prefibrillar Aggregates
  • Author : Daniel Erik Otzen
  • Publisher : John Wiley & Sons
  • Release : 04 June 2013
GET THIS BOOKAmyloid Fibrils and Prefibrillar Aggregates

Summing up almost a decade of biomedical research, this topical and eagerly awaited handbook is the first reference on the topic to incorporate recent breakthroughs in amyloid research. The first part covers the structural biology of amyloid fibrils and pre-fibrillar assemblies, including a description of current models for amyloid formation. The second part looks at the diagnosis and biomedical study of amyloid in humans and in animal models, while the final section discusses pharmacological approaches to manipulating amyloid and also

Systems Biology of Metabolic and Signaling Networks

Systems Biology of Metabolic and Signaling Networks
  • Author : Miguel A. Aon,Valdur Saks,Uwe Schlattner
  • Publisher : Springer Science & Business Media
  • Release : 22 October 2013
GET THIS BOOKSystems Biology of Metabolic and Signaling Networks

Systems Biology represents a new paradigm aiming at a whole-organism-level understanding of biological phenomena, emphasizing interconnections and functional interrelationships rather than component parts. The study of network properties, and how they control and regulate behavior from the cellular to organism level, constitutes a main focus of Systems Biology. This book addresses from a novel perspective a major unsolved biological problem: understanding how a cell works and what goes wrong in pathology. The task undertaken by the authors is in equal