Osteosarcopenia Bone Muscle and Fat Interactions

This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies. With our aging population, chronic diseases such as osteoporosis and sarcopenia are becoming highly prevalent. Fortunately, our understanding of the bone and muscle interactions has increased in recent years. This has allowed to the coining of the term osteosarcopenia to describe a syndrome in which these two diseases overlap. This overlap between osteoporosis and sarcopenia has major negative effects not only on our older adults but also on health systems worldwide. Readers will find a highly translational approach that starts with a summary of recent discoveries on stem cells biology, muscle and bone interactions – including the role of local bone and muscle fat – followed by comprehensive reviews on myokines (i.e. myostatin), osteokines (i.e. osteocalcin) and adipokines (i.e. interleukins) as major players and determinants of bone and muscle loss with aging. In addition, the role of sex steroids (i.e. estrogens, androgens), and calciotropic hormones (i.e. parathyroid hormone, vitamin D) in the pathogenesis of this syndrome is also reviewed. Moreover, using practical diagnostic and therapeutic tips, this book summarizes the clinical characteristics of osteosarcopenic patients thus facilitating the diagnosis and treatment of this syndrome in clinical practice. Finally, the book presents the case for the Falls and Fractures Clinic as the optimal model of care for this syndrome, aimed to avoid fragmentation and optimize osteosarcopenia care, and simultaneously prevent falls and fractures in older persons. This book offers relevant information on the mechanisms of osteosarcopenia, and a practical guide on how to identify and treat this geriatric syndrome and its adverse outcomes, which are dramatically affecting our aging population. The work is written by leaders in the field and is especially suited not only to any researcher in the musculoskeletal arena but also to medical specialists and allied health professionals involved in the care of older persons.

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  • Author : Gustavo Duque
  • Publisher : Springer Nature
  • Pages : 383 pages
  • ISBN : 3030258904
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKOsteosarcopenia Bone Muscle and Fat Interactions

Osteosarcopenia: Bone, Muscle and Fat Interactions

Osteosarcopenia: Bone, Muscle and Fat Interactions
  • Author : Gustavo Duque
  • Publisher : Springer Nature
  • Release : 06 November 2019
GET THIS BOOKOsteosarcopenia: Bone, Muscle and Fat Interactions

This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies. With our aging population, chronic diseases such as osteoporosis and sarcopenia are becoming highly prevalent. Fortunately, our understanding of the bone and muscle interactions has increased in recent years. This has allowed to the coining of the term osteosarcopenia to describe a syndrome in which these two diseases overlap.

Osteosarcopenia

Osteosarcopenia
  • Author : Gustavo Duque,Bruce R. Troen
  • Publisher : Elsevier
  • Release : 15 August 2021
GET THIS BOOKOsteosarcopenia

Falls, fractures, frailty, osteoporosis and sarcopenia are highly prevalent in older persons. While the concept of osteosarcopenia is new, it is a rapidly evolving and cross-disciplinary problem. Prevention and treatment are challenging and a combined therapeutic approach is needed. Osteosarcopenia provides evidence-based information on how to prevent and treat these conditions at multiple settings, including multiple illustrations, care pathways and tips to easily understand the pathophysiology, diagnostic methods and therapeutic approach to these conditions. This work evaluates the potential for

Sarcopenia

Sarcopenia
  • Author : Alfonso J. Cruz-Jentoft,John E. Morley
  • Publisher : John Wiley & Sons
  • Release : 06 July 2021
GET THIS BOOKSarcopenia

SARCOPENIA An in-depth examination of sarcopenia’s underexplored yet widespread impact within the field of gerontology Sarcopenia is common in older men and women, and yet awareness of its clinical relevance is still relatively low. Only formally included in the International Classification of Diseases in 2016, the condition may impact societies with serious health-related and financial consequences unless consistent, effective methods of identification and management are adopted. This second edition of Sarcopenia provides geriatricians and other healthcare professionals with a revised

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Encyclopedia of Biomedical Gerontology
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 20 November 2019
GET THIS BOOKEncyclopedia of Biomedical Gerontology

Encyclopedia of Biomedical Gerontology presents a wide range of topics, ranging from what happens in the body during aging, the reasons and mechanisms relating to those age-related changes, and their clinical, psychological and social modulators and determinants. The book covers the biological and medical aspects of gerontology within the general framework of the biological basis of assessing age, biological mechanisms of aging, age-related changes in biological systems, human age-related diseases, the biomedical practicality and impracticality of interventions, and finally, the

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  • Author : Paolo Falaschi,David R. Marsh
  • Publisher : Springer
  • Release : 19 September 2016
GET THIS BOOKOrthogeriatrics

This book focuses on orthogeriatrics, a topic that has received little attention in the literature to date. As active members of the Fragility Fracture Network (FFN), the editors and most of the authors of this book have gathered all essential expertise on hip fracture management in a single volume. The 14 chapters provide a complete overview of how to approach fractures in elderly patients, starting with the epidemiology of hip fractures and subsequently addressing osteoporosis, surgery, anesthesia, medical management of frailty,

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Osteoporosis in Older Persons
  • Author : Gustavo Duque,Douglas P. Kiel
  • Publisher : Springer
  • Release : 11 July 2016
GET THIS BOOKOsteoporosis in Older Persons

This new edition includes the most up-to-date information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. It is written by investigators (clinicians and basic scientists) in the field of aging bone research. It was just recently that a new syndrome, osteoporosis of advanced age, was recognized as a new entity with its own pathophysiology and potential treatments. Unfortunately, and despite the fact that hip fractures are mostly a consequence of this process, and apart from the

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Nutritional Influences on Bone Health
  • Author : Connie M. Weaver,Heike Bischoff-Ferrari,Robin M. Daly,Man-Sau Wong
  • Publisher : Springer
  • Release : 24 October 2018
GET THIS BOOKNutritional Influences on Bone Health

This book comprehensively covers the topics and discussions covered at the 10th International Symposium on Nutritional Aspects of Osteoporosis. It is the only international meeting that exclusively covers the role of nutrition on musculoskeletal health and function. Current thinking on the role of nutrition on bone and muscle development and health, and as a means of preventing osteoporosis, falls and fractures is covered. The latest evidence on the potential roles that protein, potassium, B vitamins, vitamin D, omega-3 fatty acids,

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The Osteoporosis Primer
  • Author : Janet E. Henderson,David Goltzman
  • Publisher : Cambridge University Press
  • Release : 24 August 2000
GET THIS BOOKThe Osteoporosis Primer

The Osteoporosis Primer provides an excellent introduction that relates the clinical presentation of osteoporosis to its molecular biochemical basis, and reviews therapeutic options.

Rheumatic Disease in Geriatrics

Rheumatic Disease in Geriatrics
  • Author : Gleb Slobodin,Yehuda Shoenfeld
  • Publisher : Springer Nature
  • Release : 25 May 2020
GET THIS BOOKRheumatic Disease in Geriatrics

This book provides a practical guide to the diagnosis and management of rheumatic disease in geriatric patients. It details information on the effect of ageing on musculoskeletal and immune systems and specifies impact of a variety of inflammatory and degenerative rheumatic disorders on the elderly. The clinical diagnostic approach to an older individual with musculoskeletal complaints is a cornerstone of this book, which includes also insights into the most important comorbidities for this age and discusses in depth available treatments

Hazzard's Geriatric Medicine and Gerontology, 7E

Hazzard's Geriatric Medicine and Gerontology, 7E
  • Author : Jeffrey B. Halter,Joseph G. Ouslander,Stephanie Studenski,Kevin P. High,Sanjay Asthana,Nancy Woolard,Christine S. Ritchie,Mark A. Supiano
  • Publisher : McGraw Hill Professional
  • Release : 18 November 2016
GET THIS BOOKHazzard's Geriatric Medicine and Gerontology, 7E

The gold-standard text on the diagnosis and treatment of disorders affecting the elderly – completely updated with a new full-color presentation A Doody's Core Title for 2017! The definitive treatise on the subject of geriatrics, this comprehensive text combines gerontology principles with clinical geriatrics, offering a uniquely holistic approach to this ever-expanding area of medicine. Written by some of the world’s most respected geriatricians, Hazzard’s Geriatric Medicine and Gerontology, Seventh Edition presents up-to-date, evidence-based information in a rich new full-color

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Multicellular Animals
  • Author : Peter Ax
  • Publisher : Springer Science & Business Media
  • Release : 09 March 2013
GET THIS BOOKMulticellular Animals

The system of multicellular animals presented here is an alternative to the traditional classification system. In a new approach to the phylogenetic order, this book strives for an objective systematization of the metazoa, seeking a new path in the field of academic research and teaching.

Bildverarbeitung für die Medizin 2020

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  • Author : Thomas Tolxdorff,Thomas M. Deserno,Heinz Handels,Andreas Maier,Klaus H. Maier-Hein,Christoph Palm
  • Publisher : Springer-Verlag
  • Release : 12 February 2020
GET THIS BOOKBildverarbeitung für die Medizin 2020

In den letzten Jahren hat sich der Workshop "Bildverarbeitung für die Medizin" durch erfolgreiche Veranstaltungen etabliert. Ziel ist auch 2020 wieder die Darstellung aktueller Forschungsergebnisse und die Vertiefung der Gespräche zwischen Wissenschaftlern, Industrie und Anwendern. Die Beiträge dieses Bandes - einige davon in englischer Sprache - umfassen alle Bereiche der medizinischen Bildverarbeitung, insbesondere Bildgebung und -akquisition, Maschinelles Lernen, Bildsegmentierung und Bildanalyse, Visualisierung und Animation, Zeitreihenanalyse, Computerunterstützte Diagnose, Biomechanische Modellierung, Validierung und Qualitätssicherung, Bildverarbeitung in der Telemedizin

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  • Author : Susan Y. Smith,Aurore Varela,Rana Samadfam
  • Publisher : Springer
  • Release : 27 September 2017
GET THIS BOOKBone Toxicology

The content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology industries with a broad understanding of bone and its interactions with other organ systems in safety assessments. The book is divided into three parts. The first part describes our current understanding of bone biology and its primary regulatory pathways. Additional chapters address regulatory and study design considerations for incorporating bone end points in toxicology studies, with special consideration being given to

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Body Composition and Aging
  • Author : C.V. Mobbs,P.R. Hof
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 12 August 2010
GET THIS BOOKBody Composition and Aging

Increased adiposity and decreased muscle mass contribute substantially to age-dependent disease and disability. In particular age-related increase in adiposity is quickly becoming a major threat to public health throughout the world. Although the hypothesis that age-related changes in body composition are due to lifestyle choices alone is well accepted, it is a vast oversimplification. This volume reflects the current knowledge in this rapidly developing field of research. The first part of the book discusses the extent to which increased adiposity