Overcoming Ovarian Cancer Chemoresistance

Overcoming Ovarian Cancer Chemoresistance presents non-overlapping review chapters that discuss the state of the field in overcoming chemoresistance of ovarian cancer and treatment options before and following recurrence, considering the genetic makeup of the ovarian cancer patient and her tumor. With the uptake of both germline and somatic gene testing, clinicians can obtain a more comprehensive understanding of ovarian tumors and this book provides information to link the genetic makeup of a tumor (or patient) with the best available treatment. The book discusses topics such as strategies to fight chemo-resistance in ovarian cancer, circulating DNA as a monitor of response, BRCA mutations, ovarian cancer stem cells, immunotherapy and vaccines. Additionally, it brings a list of promising agents at clinical and pre-clinical stage that will impact the treatment in the near future. This book is a valuable source for cancer researchers, oncologists and several members of biomedical field who need to understand how to battle chemoresistance in ovarian cancer. Provides a comprehensive view of both biological and genetic determinants of resistance, as well as technical approaches to monitor response Discusses genetic reversions as a unique alteration and a new field of study Includes a chapter on upcoming and promising agents that are in the pre-clinical and early clinical space, to set the stage for future directions in the field

Produk Detail:

  • Author : Goli Samimi
  • Publisher : Academic Press
  • Pages : 188 pages
  • ISBN : 0128198419
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKOvercoming Ovarian Cancer Chemoresistance

Overcoming Ovarian Cancer Chemoresistance

Overcoming Ovarian Cancer Chemoresistance
  • Author : Goli Samimi,Christina Annunziata
  • Publisher : Academic Press
  • Release : 06 November 2020
GET THIS BOOKOvercoming Ovarian Cancer Chemoresistance

Overcoming Ovarian Cancer Chemoresistance presents non-overlapping review chapters that discuss the state of the field in overcoming chemoresistance of ovarian cancer and treatment options before and following recurrence, considering the genetic makeup of the ovarian cancer patient and her tumor. With the uptake of both germline and somatic gene testing, clinicians can obtain a more comprehensive understanding of ovarian tumors and this book provides information to link the genetic makeup of a tumor (or patient) with the best available treatment.

Overcoming Drug Resistance in Gynecologic Cancers

Overcoming Drug Resistance in Gynecologic Cancers
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 01 July 2021
GET THIS BOOKOvercoming Drug Resistance in Gynecologic Cancers

Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and

Cancer Drug Resistance Research Perspectives

Cancer Drug Resistance Research Perspectives
  • Author : Liman S. Torres
  • Publisher : Nova Publishers
  • Release : 16 June 2021
GET THIS BOOKCancer Drug Resistance Research Perspectives

One of the main causes of failure in the treatment of cancer is the development of drug resistance by the cancer cells. The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer treatment that is 100% effective against disseminated cancer. Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell genetic differences in tumours, even those from the same tissue of origin. Frequently resistance is intrinsic to

Development of a Patient-derived Xenograft Model of Ovarian Cancer to Characterize the Chemotherapy Resistant Population

Development of a Patient-derived Xenograft Model of Ovarian Cancer to Characterize the Chemotherapy Resistant Population
  • Author : Zachary Christopher Dobbin
  • Publisher : Unknown Publisher
  • Release : 16 June 2021
GET THIS BOOKDevelopment of a Patient-derived Xenograft Model of Ovarian Cancer to Characterize the Chemotherapy Resistant Population

Ovarian cancer while the second most common gynecologic malignancy is the most commons cause of death due to a gynecologic malignancy and the fifth most common cause of death to cancer in women. In 2014, there will be an expected 21,980 cases and 14,270 deaths. Unfortunately, the five-year survival for ovarian cancer is only 40% and this has barely increased over the past 30 years. New approaches need to be developed in order to study ovarian cancer and identify methods of overcoming chemotherapy resistance. This

Ovarian Cancers

Ovarian Cancers
  • Author : National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Care Services,Committee on the State of the Science in Ovarian Cancer Research
  • Publisher : National Academies Press
  • Release : 25 May 2016
GET THIS BOOKOvarian Cancers

In an era of promising advances in cancer research, there are considerable and even alarming gaps in the fundamental knowledge and understanding of ovarian cancer. Researchers now know that ovarian cancer is not a single disease-several distinct subtypes exist with different origins, risk factors, genetic mutations, biological behaviors, and prognoses. However, persistent questions have impeded progress toward improving the prevention, early detection, treatment, and management of ovarian cancers. Failure to significantly improve morbidity and mortality during the past several decades

Epigenetic Alterations in Oncogenesis

Epigenetic Alterations in Oncogenesis
  • Author : Adam R. Karpf
  • Publisher : Springer Science & Business Media
  • Release : 06 September 2012
GET THIS BOOKEpigenetic Alterations in Oncogenesis

The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher

PIPAC

PIPAC
  • Author : Marc A. Reymond,Wiebke Solass
  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release : 14 October 2014
GET THIS BOOKPIPAC

Peritoneal dissemination is a common route of cancer metastasis. The benefit of administering chemotherapy directly into the peritoneal cavity is supported by preclinical and pharmacokinetic data. In comparison to intravenous (IV) treatment, intraperitoneal (IP) administration results in a several-fold increase in drug concentration within the abdominal cavity. There is now growing evidence from clinical studies showing a survival advantage for IP chemotherapy in various tumor typies, including ovarian, gastric and colorectal cancer. However, while the use of IP chemotherapy is

Your Life in Your Hands

Your Life in Your Hands
  • Author : Jane A. Plant
  • Publisher : Random House
  • Release : 16 June 2021
GET THIS BOOKYour Life in Your Hands

"Professor Jane Plant s international bestseller on combating breast cancer through diet and lifestyle changes has been fully revised and updated, including new information on ovarian cancer and other types of cancer. In this groundbreaking book, Professor Plant details her own experiences of suffering with breast cancer, and how she learnt of the relationship between the disease and diet. The book explains the science behind the no dairy diet and gives practical advice on how diet and lifestyle changes can

Beating Ovarian Cancer

Beating Ovarian Cancer
  • Author : Chris Bledy
  • Publisher : Chris Bledy
  • Release : 16 June 2021
GET THIS BOOKBeating Ovarian Cancer

A diagnosis of Ovarian Cancer does not have to be a death sentence. Recent advances in medicine have made this once incurable disease treatable and manageable. You can beat advanced and even recurring, ovarian cancer. Simple but significant lifestyle changes can produce big results when it comes to healing.

Targeting Ovarian Cancer Through Epigallocatechin Gallate and Sulforaphane Combinatorial Treatment

Targeting Ovarian Cancer Through Epigallocatechin Gallate and Sulforaphane Combinatorial Treatment
  • Author : Huaping Chen
  • Publisher : Unknown Publisher
  • Release : 16 June 2021
GET THIS BOOKTargeting Ovarian Cancer Through Epigallocatechin Gallate and Sulforaphane Combinatorial Treatment

The cellular development of resistance to chemotherapy contributes to the high mortality noted in patients affected by ovarian cancer. Novel compounds that can enhance efficacy of conventional chemotherapy or target both drug-sensitive and -resistant ovarian cancers directly are highly desired. Previous epidemiological studies indicate that consumption of green tea and cruciferous vegetables is inversely associated with occurrence of ovarian cancer. Therefore, revealing the effects and mechanisms of major components of green tea (epigallocatechin gallate, EGCG) and cruciferous vegetables (sulforaphane, SFN)

Ovarian Cancer

Ovarian Cancer
  • Author : Anastasia Malek,Oleg Tchernitsa
  • Publisher : Humana Press
  • Release : 03 August 2013
GET THIS BOOKOvarian Cancer

Ovarian cancer is the most lethal malignancy of the female reproductive system and is also the fifth leading cause of cancer death in women. Sharing common characteristics of cancer, ovarian malignancy possess several clinical and biological particularities In Ovarian Cancer: Methods and Protocols, expert researchers in the field provide methods that have been created or adapted to study various aspects of ovarian cancer. These methods and techniques are applicable to study genetic alterations present in ovarian cancer, structural and metabolic