Placebo and Pain

The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers’ knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain. Review for Placebo and Pain: “This ambitious book is the first comprehensive and unified presentation of the placebo and nocebo phenomena in the area of pain. Written by the international leading experts in the field, the book provides an accurate up-to-date [work] on placebo and pain dealing with current perspectives and future challenging issues. --Ted Kaptchuk, Associate Professor of Medicine, Harvard Medical School Contains historical aspects of the placebo effect Discusses biological and psychological mechanisms of placebo analgesic responses Reviews implications of the placebo effect for clinical research and pain management Includes methodological and ethical aspects of the placebo effect

Produk Detail:

  • Author : Luana Colloca
  • Publisher : Academic Press
  • Pages : 312 pages
  • ISBN : 0123979315
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKPlacebo and Pain

Placebo and Pain

Placebo and Pain
  • Author : Luana Colloca,Magne Arve Flaten,Karin Meissner
  • Publisher : Academic Press
  • Release : 28 August 2013
GET THIS BOOKPlacebo and Pain

The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers’ knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves

Placebo and Pain

Placebo and Pain
  • Author : Harald Walach
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
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Complementary and alternative medicine (CAM) is frequently conceptualized as ‘nothing but’ placebo. I will argue, and provide the evidence in this chapter, that, apart from potential specific effects, CAM is a clever way of inducing generic self-healing effects. Jerome D Frank's model serves to conceptualize this. CAM practitioners normally establish good relationships and take time to listen to their patients. They have very elaborate rituals to enact those effects. They demonstrate their prowess and they provide alternative explanatory models that

Placebo and Pain

Placebo and Pain
  • Author : Regine Klinger,Herta Flor
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
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In this chapter we discuss the various aspects of the clinical applications of placebo effects. In clinical studies, a placebo intervention is often nearly as potent as the effects of the verum that is applied, and placebo effects can have enduring positive consequences. Most research has focused on healthy humans and it is not clear whether the results reported in these people can be transferred to clinical populations. Initial studies on this topic have suggested that patients may profit more

Topical Issues in Pain 4

Topical Issues in Pain 4
  • Author : Louis Gifford
  • Publisher : Author House
  • Release : 01 September 2013
GET THIS BOOKTopical Issues in Pain 4

This fourth volume contains further ground-breaking and highly relevant work. Taking on the placebo and nocebo phenomenon, pain management and muscles and pain the volume yet again promotes the forward thinking and cutting edge work of the Physiotherapy Pain Association. In Part 1 a number of internationally renowned clinicians and researchers have come together to produce the first published attempt to broadly address and critically appraise the placebo and nocebo phenomenon from a clinical perspective for physiotherapists. The information and the

Placebo and Pain

Placebo and Pain
  • Author : Lene Vase,Gitte Laue Petersen
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
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The magnitude of placebo analgesia effects has been shown to vary across meta-analyses. The conceptualization of placebo effects, and the way in which they are induced, influence the magnitude of placebo analgesia effects. This has been indicated by meta-analyses and further confirmed by experimental studies. In general, small placebo analgesia effects are found in clinical trials in which placebo is used as a control condition, whereas large effects are found in placebo mechanism studies investigating how expectations and emotional feelings

Placebo and Pain

Placebo and Pain
  • Author : Magne Arve Flaten,Karin Meissner,Luana Colloca
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
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Studies of placebo analgesia necessarily involve the induction and reporting of pain. The pain report is the basic dependent variable in many studies of placebo analgesia, and reported pain should ideally reflect the pain experience. However, the pain report is subject to a number of different influences that threaten the internal validity of research on pain and, consequently, placebo analgesia. The study of placebo analgesia introduces several other issues, in terms of the design of studies that researchers must deal

Placebo and Pain

Placebo and Pain
  • Author : Magne Arve Flaten,Per M. Aslaksen,Peter S. Lyby
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
GET THIS BOOKPlacebo and Pain

Pain may be modulated by positive and negative emotions, and this is the basic element in the hypothesis that placebo effects are due to a reduction in negative emotions. Individual differences are discussed, especially as they relate to negative emotions. There is evidence that the placebo effect is partly due to a reduction in negative emotions. The role of positive emotions in placebo analgesia is less studied, and the data are mixed. The nocebo effect, the opposite of the placebo

Placebo and Pain

Placebo and Pain
  • Author : Serge Marchand
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
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There is good evidence that placebo and nocebo responses reflect more than a psychologic reappraisal of pain perception. In fact, pain perception is the endpoint of several endogenous pain inhibitory and facilitatory mechanisms that trigger descending pain modulation mechanisms to the spinal cord. Measuring the ability of placebo and nocebo to act on these mechanisms will demonstrate that their effects are not only a reinterpretation of higher centers of the same nociceptive signal, but are acting at the source of

Placebo and Pain

Placebo and Pain
  • Author : Ben Colagiuri,Peter F. Lovibond
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
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Evidence from both empirical studies and clinical practice indicates that substantial reductions in pain can be observed following placebo treatment. Generally, these effects are attributed to expectancy and/or classic conditioning. However, other psychological processes that could bias the observed responses to placebo treatment may lead to a systematic over- or underestimate of the magnitude of the placebo effect. First, demand characteristics could encourage participants or patients to respond in a way consistent with their perceptions of the study’s

Placebo and Pain

Placebo and Pain
  • Author : Luana Colloca,Franklin G. Miller
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
GET THIS BOOKPlacebo and Pain

The defining circumstances and reasons for promoting healing processes based on placebo and avoiding (undesirable) nocebo effects in clinical practice represent a challenge for translational and patient-oriented medicine. Exploiting placebos and placebo effects for the benefit of the patient requires a rigorous evaluation of potential benefits and harms associated with these interventions. Moreover, any attempts to harness placebo benefits and mitigate nocebo effects in clinical practice should be done consistently with professional norms and integrity, and ethical-legal requirements of informed

Placebo and Pain

Placebo and Pain
  • Author : Damien Finniss
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
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The placebo effect has been a topic of interest in medicine for many hundreds of years. A historical evaluation of the topic demonstrates how the origin of the word, and its initial use in society and in medicine, has shaped its meaning over many years. In fact, the understanding of placebo effects is only now changing, largely due to an exponential rise in dedicated research into placebo mechanisms, clinical applications, and publications promoting re-evaluation of many longstanding interpretations of the

Placebo and Pain

Placebo and Pain
  • Author : Karin Meissner,Klaus Linde
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
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More invasive and impressive therapeutic rituals are generally believed to be more powerful interventions than less impressive ones. This chapter reviews and discusses evidence from randomized clinical trials and meta-analyses for such a differential effectiveness of placebo interventions. Evidence from clinical research that different types of placebo are regularly associated with different magnitudes of placebo effect is limited. However, one area where hints from a variety of sources are accumulating is sham acupuncture in the treatment of pain. Furthermore, there

Placebo and Pain

Placebo and Pain
  • Author : Ulrike Bingel
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
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The observation that cognitive factors, such as beliefs, expectations and prior experiences, not only modulate the perception of pain but also the therapeutic benefit and adverse effects of pharmacologic treatments is not new. However, to date, the contribution of cognitive factors to pharmacotherapy is still poorly understood and far from being systematically exploited to maximize treatment outcome. This chapter gives an overview on the contribution of placebo and nocebo mechanisms to the outcome of analgesic treatments, insights into the neurobiologic

Placebo and Pain

Placebo and Pain
  • Author : Falk Eippert,Christian Büchel
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
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Placebo analgesia is an illustrative example of the impact that psychological factors can have on the experience of pain. While this form of pain modulation is mediated by multiple neurobiological mechanisms, one influential explanation posits that a descending pain control system contributes to placebo effects in pain. Here, we first give an overview of descending pain control as established in animal studies, focusing on an opioid-dependent system that includes the periaqueductal gray (PAG) and rostral ventromedial medulla (RVM) as core

Placebo and Pain

Placebo and Pain
  • Author : Jian Kong,Randy L. Gollub
  • Publisher : Elsevier Inc. Chapters
  • Release : 28 August 2013
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For thousands of years, both acupuncture and placebo (as a therapeutic ritual) have been used in healing. It is only recently that scientists have begun rigorously investigating the efficacy of acupuncture treatment. Recent meta analysis suggests that acupuncture treatment is only moderately more effective than sham treatment on some pain disorders such as osteoarthritis, headache, musculoskeletal and shoulder pain, which suggests that non-specific components are important contributors to the therapeutic benefits of acupuncture treatment. This chapter discusses the challenges involved