Recent Advances in iPSC Disease Modeling Volume 1

Recent Advances in iPSC Disease Modeling, Volume 1 addresses how induced pluripotent stem cells can be used to model various diseases. Somatic cells are reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. This volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to model several diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. Further insights into these mechanisms will have important implications for our understanding of disease appearance, development, and progression. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues, and organs using state-of-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of induced pluripotent stem cell technology, regenerative medicine, and therapeutics Covers the following diseases: severe congenital neutropenia, sickle cell and Diamond-Blackfan anemias, muscular dystrophies, Bernard-Soulier syndrome, familial hypercholesterolemia type II A, Werner syndrome, lysosomal storage diseases, and more Contains description of cutting-edge research on the development of disease-specific human pluripotent stem cells. These cells allow us to study cellular and molecular processes involved in several human diseases

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  • Author : ALEXANDER BIRBRAIR
  • Publisher : Academic Press
  • Pages : 320 pages
  • ISBN : 0128232692
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKRecent Advances in iPSC Disease Modeling Volume 1

Recent Advances in iPSC Disease Modeling, Volume 1

Recent Advances in iPSC Disease Modeling, Volume 1
  • Author : ALEXANDER BIRBRAIR
  • Publisher : Academic Press
  • Release : 16 July 2020
GET THIS BOOKRecent Advances in iPSC Disease Modeling, Volume 1

Recent Advances in iPSC Disease Modeling, Volume 1 addresses how induced pluripotent stem cells can be used to model various diseases. Somatic cells are reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. This volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to model several diseases in vitro, enabling us to study the cellular and molecular

Stem Cells and Cancer Stem Cells, Volume 10

Stem Cells and Cancer Stem Cells, Volume 10
  • Author : M.A. Hayat
  • Publisher : Springer Science & Business Media
  • Release : 20 March 2013
GET THIS BOOKStem Cells and Cancer Stem Cells, Volume 10

Presenting contributions by 66 experts representing 13 countries, Volume 10 of the series Stem Cells and Cancer Stem Cells synthesizes current understanding of the causes, diagnosis, and therapy of major human diseases and debilitating tissue and organ injuries, using cell-based treatment. This volume presents contemporary research into generation, preservation, and uses of stem cells in fighting disease and tissue/organ injuries. The contents of the volume are organized into five sections. Mesenchymal Stem Cells section includes chapters on the use of stem cells

Recent Advances in Parkinson's Disease

Recent Advances in Parkinson's Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 02 April 2020
GET THIS BOOKRecent Advances in Parkinson's Disease

Recent Advances in Parkinson ́s Disease Research, Volume 252, represents a follow-up on two previous volumes presented in the Progress in Brain Research series, Volumes 193 and 193, both published in 2010. It contains a collection of overview articles written by leading researchers in Parkinson's, discussing the most important advances made in basic, translational and clinical research. Topics of note in this new release include What can we learn from iPS cell models of PD, What can we learn from animal models of PD?,

Recent Advances in Parkinson's Disease: Basic research

Recent Advances in Parkinson's Disease: Basic research
  • Author : Anders Björklund,M. Angela Cenci
  • Publisher : Elsevier
  • Release : 15 January 2021
GET THIS BOOKRecent Advances in Parkinson's Disease: Basic research

Neuroendocrinology is a discipline which originated about 50 years ago as a branch of Endocrinology and that is now strictly linked to neuroscience. Volumes 181 and 182 of Progress in Brain Research provide a rapid view of the major points presently discussed at biological and clinical levels. The chapters have been written by top scientists who are directly involved in basic or clinical research and who use the most sophisticated biotechnological techniques. The volumes cover of the role of genetics in many endocrine-related

Single-Cell Omics

Single-Cell Omics
  • Author : Debmalya Barh,Vasco Azevedo
  • Publisher : Academic Press
  • Release : 06 June 2019
GET THIS BOOKSingle-Cell Omics

Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the

Pluripotent Stem Cells

Pluripotent Stem Cells
  • Author : Minoru Tomizawa
  • Publisher : BoD – Books on Demand
  • Release : 20 July 2016
GET THIS BOOKPluripotent Stem Cells

Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine.

Medical Applications of iPS Cells

Medical Applications of iPS Cells
  • Author : Haruhisa Inoue,Yukio Nakamura
  • Publisher : Springer
  • Release : 01 April 2019
GET THIS BOOKMedical Applications of iPS Cells

This volume highlights recent advances using iPS cells in disease modeling and medical applications along with new technologies that enhance the power of iPS cells. While the discovery of iPS cells has provided excellent opportunities for developing models of human diseases, platforms for drug discovery and cell therapies, iPS cell technology still faces many challenges. Presenting the latest advances in this rapidly evolving research area, this book is intended to widen the community of researchers and clinicians interested in the

Pluripotent Stem Cells

Pluripotent Stem Cells
  • Author : Deepa Bhartiya,Nibedita Lenka
  • Publisher : BoD – Books on Demand
  • Release : 28 August 2013
GET THIS BOOKPluripotent Stem Cells

Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown

Muscle Cell and Tissue

Muscle Cell and Tissue
  • Author : Kunihiro Sakuma
  • Publisher : BoD – Books on Demand
  • Release : 02 September 2015
GET THIS BOOKMuscle Cell and Tissue

In order to complete tissue regeneration, various cells such as neuronal, skeletal, smooth, endothelial, and immune (e.g., macrophage) interact smoothly with each other. This book, Muscle Cells and Tissues, offers a wide range of topics such as stem cells, cell culture, biomaterials, epigenetics, therapeutics, and the creation of tissues and organs. Novel applications for cell and tissue engineering including cell therapy, tissue models, and disease pathology modeling are discussed. The book also deals with the functional role of autophagy

Tissue Regeneration

Tissue Regeneration
  • Author : Hussein Abdelhay Essayed Kaoud
  • Publisher : BoD – Books on Demand
  • Release : 06 June 2018
GET THIS BOOKTissue Regeneration

Tissue regeneration is a vast subject, with many different important aspects to consider. Regenerative medicine is a new branch of medicine that tries to change the course of chronic diseases and, in many cases, regenerates the organ systems that fail due to age, disease, damage, or genetic defects. The main purpose of this book is to point out the interest of some important topics of tissue regeneration and the progress in this field as well as the variety of different

Skin Tissue Models

Skin Tissue Models
  • Author : Alexandra P. Marques,Rui L Reis,Rogério P. Pirraco,Mariana Cerqueira
  • Publisher : Academic Press
  • Release : 14 November 2017
GET THIS BOOKSkin Tissue Models

Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury – from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing,

iPSCs for Modeling Central Nervous System Disorders, Volume 6

iPSCs for Modeling Central Nervous System Disorders, Volume 6
  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release : 01 May 2021
GET THIS BOOKiPSCs for Modeling Central Nervous System Disorders, Volume 6

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSC Central Nervous System Disease Modeling, Volume 13 addresses how important induced pluripotent stems cells are and how they can be used to model CNS disorders. The creation of iPSC technology allowed the development of disease-specific human pluripotent stem cells. These cells allow researchers to study questions impossible before for some human diseases. This volume

Cell Biology and Translational Medicine, Volume 7

Cell Biology and Translational Medicine, Volume 7
  • Author : Kursad Turksen
  • Publisher : Springer Nature
  • Release : 03 February 2020
GET THIS BOOKCell Biology and Translational Medicine, Volume 7

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as

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  • Author : Vahid Serpooshan,Sean M. Wu
  • Publisher : Springer
  • Release : 29 June 2019
GET THIS BOOKCardiovascular Regenerative Medicine

This book is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of cardiovascular disease. It provides a much-needed review of the rapid development and evolution of bio-fabrication techniques to engineer cardiovascular tissues as well as their use in clinical settings. The book incorporates recent advances in the biology, biomaterial design, and manufacturing of bioengineered cardiovascular tissue with their clinical applications to bridge the basic sciences to current and future cardiovascular treatment. The book begins

Neurodevelopmental Disorders

Neurodevelopmental Disorders
  • Author : Bin Chen,Kenneth Y. Kwan
  • Publisher : Academic Press
  • Release : 24 May 2020
GET THIS BOOKNeurodevelopmental Disorders

Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development