Resident Stem Cells and Regenerative Therapy

In the last 3 decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures. This book will present the main findings to date and the important factors to be considered when considering resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin, and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate. Highlights basic research in tissue specific stem cells, experiments with animal models and clinical trials that are transforming the field of regeneration Provides a clear understanding of endogenous stem cells, their role in current regenerative therapies, and prospects for future research Reports on the main-stream clinical approaches and in vivo experiments published in primary literature to help categorizes the advances in various aspects of regenerative therapy and illustrate opportunities for clinical applications

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  • Author : Regina Coeli dos Santos Goldenberg
  • Publisher : Academic Press
  • Pages : 270 pages
  • ISBN : 0124160123
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKResident Stem Cells and Regenerative Therapy

Resident Stem Cells and Regenerative Therapy

Resident Stem Cells and Regenerative Therapy
  • Author : Regina Coeli dos Santos Goldenberg,Antonio Carlos Campos de Carvalho
  • Publisher : Academic Press
  • Release : 29 June 2022
GET THIS BOOKResident Stem Cells and Regenerative Therapy

In the last 3 decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the

Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine
  • Author : Walter C. Low,Catherine M. Verfaillie
  • Publisher : World Scientific
  • Release : 29 June 2022
GET THIS BOOKStem Cells and Regenerative Medicine

The commercialization of biotechnology has resulted in an intensive search for new biological resources for the purposes of increasing food productivity, medicinal applications, energy production, and various other applications. Although biotechnology has produced many benefits for humanity, the exploitation of the planet's natural resources has also resulted in some undesirable consequences such as diminished species biodiversity, climate change, environmental contamination, and intellectual property right and patent concerns.This book discusses the role of biological, ecological, environmental, ethical, and economic issues

Principles of Regenerative Medicine

Principles of Regenerative Medicine
  • Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
  • Publisher : Academic Press
  • Release : 16 December 2010
GET THIS BOOKPrinciples of Regenerative Medicine

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure.

Fetal Stem Cells in Regenerative Medicine

Fetal Stem Cells in Regenerative Medicine
  • Author : Dario O. Fauza,Mahmud Bani
  • Publisher : Springer
  • Release : 02 May 2016
GET THIS BOOKFetal Stem Cells in Regenerative Medicine

This book explores the regenerative properties of fetal stem cells, from feto-maternal cell traffic through perinatal stem cells, with a discussion of key topics including stem cell banking, drug screening, in utero stem cell transplantation and ethical considerations. The expertly authored chapters also delve into embryonic, amniotic membrane, and umbilical cord blood stem cells; fetal development models; fetal cell reprogramming; culture methods; disease models; perinatal gene therapy, and more. These chapters are grouped into four sections, each discussing a separate

Stem Cells and Aging

Stem Cells and Aging
  • Author : Surajit Pathak,Antara Banerjee
  • Publisher : Academic Press
  • Release : 17 March 2021
GET THIS BOOKStem Cells and Aging

Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began in 1963 when James Till, Ernest McCullough and Lou Siminovitch established assays to detect hematopoietic stem cells. In fact, given the importance of the aging-associated diseases, scientists have developed a keen

Stem Cell Biology and Regenerative Medicine in Ophthalmology

Stem Cell Biology and Regenerative Medicine in Ophthalmology
  • Author : Stephen Tsang
  • Publisher : Springer Science & Business Media
  • Release : 09 December 2012
GET THIS BOOKStem Cell Biology and Regenerative Medicine in Ophthalmology

Patient specific and disease specific stem cell lines have already introduced groundbreaking advances into the research and practice of ophthalmology. This volume provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modelling, drug screening and gene targeting to clinical genetics and regenerative treatments. Innovative results from stem cell research of the past decade are pointing the way toward practicable treatments for retinitis

Progenitor and Stem Cell Technologies and Therapies

Progenitor and Stem Cell Technologies and Therapies
  • Author : Anthony Atala
  • Publisher : Elsevier
  • Release : 15 March 2012
GET THIS BOOKProgenitor and Stem Cell Technologies and Therapies

Progenitor and stem cells have the ability to renew themselves and change into a variety of specialised types, making them ideal materials for therapy and regenerative medicine. Progenitor and stem cell technologies and therapies reviews the range of progenitor and stem cells available and their therapeutic application. Part one reviews basic principles for the culture of stem cells before discussing technologies for particular cell types. These include human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells. Part

Resident Stem Cells and Regenerative Therapy

Resident Stem Cells and Regenerative Therapy
  • Author : Regina Coeli dos Santos Goldenberg,Antonio Carlos Campos de Carvalho
  • Publisher : Academic Press
  • Release : 31 December 2012
GET THIS BOOKResident Stem Cells and Regenerative Therapy

In the last 3 decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the

Adult Stem Cells in Aging, Diseases and Cancer

Adult Stem Cells in Aging, Diseases and Cancer
  • Author : K.L. Rudolph
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 22 December 2014
GET THIS BOOKAdult Stem Cells in Aging, Diseases and Cancer

The functionality of adult tissue stem cells from various organ systems declines during aging. This publication summarizes novel molecular mechanisms responsible for the development of aging-associated deficiencies as discussed by leading experts during the 5th Else Kröner-Fresenius Symposium. It is the first book that explicitly focuses on molecular mechanisms of stem cell aging and its consequences for disease and cancer development including both cell-intrinsic mechanisms as well as aging-induced alterations in the stem cell niche and the systemic environment.

Adult Stem Cells

Adult Stem Cells
  • Author : Donald G. Phinney
  • Publisher : Springer Science & Business Media
  • Release : 11 February 2011
GET THIS BOOKAdult Stem Cells

This is comprehensive overview of a vital area of scientific enquiry, which covers a broad spectrum of issues. With contributions from some of the key researchers in the field, Adult Stem Cells: Biology and Methods of Analysis offers readers a historical perspective as well as unique insights into cutting-edge thoughts. The volume contextualizes the recent discovery of stem/progenitor cell populations resident in many adult tissues and organs. It confronts the complexities scientists face in trying to validate these cells,

Stem Cell Assays

Stem Cell Assays
  • Author : Nagarajan Kannan,Philip Beer
  • Publisher : Humana
  • Release : 05 May 2022
GET THIS BOOKStem Cell Assays

This volume explores the fields of stem cell biology, regenerative medicine, and cancer biology. The chapters in this book cover topics such as embryonic stem cells (ES) and induced pluripotent cells (iPS); ES/iPSC derived tissue stem cells; tissue resident stem cells; assays for primitive malignant cells; and CRISPR/Cas9 engineering and transgenic model development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents,

Stem Cell and Gene Therapy for Cardiovascular Disease

Stem Cell and Gene Therapy for Cardiovascular Disease
  • Author : Emerson C. Perin,Leslie W. Miller,Doris Taylor,James T. Willerson
  • Publisher : Academic Press
  • Release : 21 August 2015
GET THIS BOOKStem Cell and Gene Therapy for Cardiovascular Disease

Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials.

Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
  • Author : Lucas G. Chase,Mohan C Vemuri
  • Publisher : Springer Science & Business Media
  • Release : 12 December 2012
GET THIS BOOKMesenchymal Stem Cell Therapy

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host

Extracellular Matrix Enhances Therapeutic Effects of Stem Cells in Regenerative Medicine

Extracellular Matrix Enhances Therapeutic Effects of Stem Cells in Regenerative Medicine
  • Author : Yan Nie
  • Publisher : Unknown Publisher
  • Release : 29 June 2022
GET THIS BOOKExtracellular Matrix Enhances Therapeutic Effects of Stem Cells in Regenerative Medicine

Stem cell therapy is a promising option for regenerative of injured or diseased tissues. However, the extremely low survival and engraftment of transplanted cells and the obviously inadequate recruitment and activation of the endogenous resident stem cells are the major challenges for stem cell therapy. Fortunately, recent progresses show that extracellular matrix (ECM) could not only act as a spatial and mechanical scaffold to enhance cell viability but also provide a supportive niche for engraftment or accelerating stem cell differentiation.

Composition and Function of the Extracellular Matrix in the Human Body

Composition and Function of the Extracellular Matrix in the Human Body
  • Author : Francesco Travascio
  • Publisher : BoD – Books on Demand
  • Release : 15 June 2016
GET THIS BOOKComposition and Function of the Extracellular Matrix in the Human Body

The extracellular matrix (ECM) is an ensemble of non-cellular components present within all tissues and organs of the human body. The ECM provides structural support for scaffolding cellular constituents and biochemical and biomechanical support for those events leading to tissue morphogenesis, differentiation and homeostasis. Essential components of all ECMs are water, proteins and polysaccharides. However, their composition, architecture and bioactivity greatly vary from tissue to tissue in relation to the specific role the ECM is required to assume. This book