RNA Based Regulation in Human Health and Disease

RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic Features contributions from leading experts in the field

Produk Detail:

  • Author : Anonim
  • Publisher : Academic Press
  • Pages : 444 pages
  • ISBN : 0128171944
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKRNA Based Regulation in Human Health and Disease

RNA-Based Regulation in Human Health and Disease

RNA-Based Regulation in Human Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 19 August 2020
GET THIS BOOKRNA-Based Regulation in Human Health and Disease

RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA

microRNA Regulation in Health and Disease

microRNA Regulation in Health and Disease
  • Author : Clifford J. Steer,Subbaya Subramanian
  • Publisher : MDPI
  • Release : 21 February 2020
GET THIS BOOKmicroRNA Regulation in Health and Disease

MicroRNAs (miRNAs) are small regulatory RNAs that play a crucial role in posttranscriptional gene regulation. Over two thousand miRNAs have been identified in humans, and many of them are conserved in other species. miRNAs are implicated in fundamental cellular functions, including development and disease. In the last decade, there has been an overwhelming amount of data contributing to the understanding of miRNA biogenesis and their target genes. Moreover, a significant amount of work has been carried out in developing miRNA

Epigenetics and Reproductive Health

Epigenetics and Reproductive Health
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 12 September 2020
GET THIS BOOKEpigenetics and Reproductive Health

Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted

Epigenetics Methods

Epigenetics Methods
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release : 08 July 2020
GET THIS BOOKEpigenetics Methods

In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics. As the field of epigenetics continues to grow, methods and technologies have multiplied, resulting in a wide range of approaches and tools researchers might employ. Epigenetics Methods offers comprehensive instruction in methods, protocols, and experimental approaches applied in field of epigenetics. Here, across thirty-five chapters, specialists offer step-by-step overviews of methods used

Epigenetics of the Immune System

Epigenetics of the Immune System
  • Author : Dieter Kabelitz,Jaydeep Bhat
  • Publisher : Academic Press
  • Release : 04 June 2020
GET THIS BOOKEpigenetics of the Immune System

Epigenetics of the Immune System focuses on different aspects of epigenetics and immunology, providing readers with the fundamental mechanisms relating to epigenetics and the immune system. This book provides in-depth information on immune cells as a toolbox in deciphering systematically regulated mechanisms using "omics" and computational biology approaches. In addition, the book presents the translational importance of epigenetics and the immune system in our understanding of pathophysiology in diseases and its therapeutic applications. Provides an overview of most important immune

microRNA Regulation in Health and Disease

microRNA Regulation in Health and Disease
  • Author : Clifford Steer,Subree Subramanian
  • Publisher : Unknown Publisher
  • Release : 09 August 2022
GET THIS BOOKmicroRNA Regulation in Health and Disease

MicroRNAs (miRNAs) are small regulatory RNAs that play a crucial role in posttranscriptional gene regulation. Over two thousand miRNAs have been identified in humans, and many of them are conserved in other species. miRNAs are implicated in fundamental cellular functions, including development and disease. In the last decade, there has been an overwhelming amount of data contributing to the understanding of miRNA biogenesis and their target genes. Moreover, a significant amount of work has been carried out in developing miRNA

Cancer and Noncoding RNAs

Cancer and Noncoding RNAs
  • Author : Jayprokas Chakrabarti,Sanga Mitra
  • Publisher : Academic Press
  • Release : 13 October 2017
GET THIS BOOKCancer and Noncoding RNAs

Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail

Nutrigenomics and Proteomics in Health and Disease

Nutrigenomics and Proteomics in Health and Disease
  • Author : Martin Kussmann,Patrick J. Stover
  • Publisher : John Wiley & Sons
  • Release : 08 May 2017
GET THIS BOOKNutrigenomics and Proteomics in Health and Disease

"This volume brings together leading experts in the areas of nutrition, nutrigenomics, metabolic programming, food-based bioactive dietary components and the gut microbiome, as well as those expert in the application of innovative tools and methods for statistical and biological network analysis, which are now at the forefront of nutritional and biomedical sciences. The articles provide a roadmap for the integration of normative science methods and approaches with more comprehensive systems biology-based investigations that deploy a multitude of omic platforms. This

The Human Genome in Health and Disease

The Human Genome in Health and Disease
  • Author : Tore Samuelsson
  • Publisher : Garland Science
  • Release : 07 February 2019
GET THIS BOOKThe Human Genome in Health and Disease

The human genome is a linear sequence of roughly 3 billion bases and information regarding this genome is accumulating at an astonishing rate. Inspired by these advances, The Human Genome in Health and Disease: A Story of Four Letters explores the intimate link between sequence information and biological function. A range of sequence-based functional units of the genome are discussed and illustrated with inherited disorders and cancer. In addition, the book considers valuable medical applications related to human genome sequencing, such

Redox Signaling and Regulation in Biology and Medicine

Redox Signaling and Regulation in Biology and Medicine
  • Author : Claus Jacob,Paul G. Winyard
  • Publisher : John Wiley & Sons
  • Release : 06 May 2009
GET THIS BOOKRedox Signaling and Regulation in Biology and Medicine

This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox processes, demonstrating that complex science can be presented in a clear and almost entertaining way. Perfect for students and junior researchers, this is an equally valuable addition to courses in biochemistry, molecular biology, cell biology, and human physiology.

Advances in RNA Research and Application: 2013 Edition

Advances in RNA Research and Application: 2013 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release : 21 June 2013
GET THIS BOOKAdvances in RNA Research and Application: 2013 Edition

Advances in RNA Research and Application / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Viral RNA. The editors have built Advances in RNA Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Viral RNA in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in RNA Research and Application: 2013 Edition has

RNA Diseases in Humans – From Fundamental Research to Therapeutic Applications

RNA Diseases in Humans – From Fundamental Research to Therapeutic Applications
  • Author : Naoyuki Kataoka,Akila Mayeda,Kinji Ohno
  • Publisher : Frontiers Media SA
  • Release : 15 October 2019
GET THIS BOOKRNA Diseases in Humans – From Fundamental Research to Therapeutic Applications

This Research Topic addresses the human diseases caused by a malfunction of the RNA metabolism. We aim at strengthening the link between fundamental research and therapeutic applications. In eukaryotes, RNA is transcribed from genomic DNA. RNA molecules undergo multiple post-transcriptional processes such as splicing, editing, modification, translation, and degradation. A defect, mis-regulation, or malfunction of these processes often results in diseases in humans, referred to as 'RNA diseases'. There is an increasing number of studies focused on RNA diseases, which

Human Molecular Genetics

Human Molecular Genetics
  • Author : Peter Sudbery,Ian Sudbery
  • Publisher : Benjamin-Cummings Publishing Company
  • Release : 09 August 2022
GET THIS BOOKHuman Molecular Genetics

This is a concise overview of a complex and fast moving field. The text explains amongst many things the special problems encountered in human genome analysis. Boxed case studies are incorporated to help student comprehension of this topic.