Selection of the HPLC Method in Chemical Analysis

• Author : Serban C. Moldoveanu,Victor David
• Publisher : Elsevier
• Release : 01 November 2016

Selection of the HPLC Method in Chemical Analysis serves as a practical guide to users of high-performance liquid chromatography and provides criteria for method selection, development, and validation. High-performance liquid chromatography (HPLC) is the most common analytical technique currently practiced in chemistry. However, the process of finding the appropriate information for a particular analytical project requires significant effort and pre-existent knowledge in the field. Further, sorting through the wealth of published data and literature takes both time and effort away

• Author : Anonim
• Publisher : Unknown Publisher
• Release : 19 May 2021

• Author : Dr. B. K. Sharma
• Publisher : Krishna Prakashan Media
• Release : 19 May 1981

• Author : Satinder Ahuja,Henrik Rasmussen
• Publisher : Elsevier
• Release : 21 September 2011

High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes

• Author : Somenath Mitra
• Publisher : Wiley-Interscience
• Release : 26 September 2003

The importance of accurate sample preparation techniques cannot be overstated--meticulous sample preparation is essential. Often overlooked, it is the midway point where the analytes from the sample matrix are transformed so they are suitable for analysis. Even the best analytical techniques cannot rectify problems generated by sloppy sample pretreatment. Devoted entirely to teaching and reinforcing these necessary pretreatment steps, Sample Preparation Techniques in Analytical Chemistry addresses diverse aspects of this important measurement step. These include: * State-of-the-art extraction techniques for organic

• Author : Mark Stauffer
• Publisher : BoD – Books on Demand
• Release : 25 April 2018

This book seeks to introduce the reader to current methodologies in analytical calibration and validation. This collection of contributed research articles and reviews addresses current developments in the calibration of analytical methods and techniques and their subsequent validation. Section 1, "Introduction," contains the Introductory Chapter, a broad overview of analytical calibration and validation, and a brief synopsis of the following chapters. Section 2 "Calibration Approaches" presents five chapters covering calibration schemes for some modern analytical methods and techniques. The last chapter in

• Author : Peter C. Meier,Richard E. Zünd
• Publisher : John Wiley & Sons
• Release : 04 March 2005

This new edition of a successful, bestselling book continues toprovide you with practical information on the use of statisticalmethods for solving real-world problems in complex industrialenvironments. Complete with examples from the chemical andpharmaceutical laboratory and manufacturing areas, this thoroughlyupdated book clearly demonstrates how to obtain reliable results bychoosing the most appropriate experimental design and dataevaluation methods. Unlike other books on the subject, Statistical Methods inAnalytical Chemistry, Second Edition presents and solves problemsin the context of a comprehensive decision-making process under

• Author : D. T. E. Hunt,Anthony Leslie Wilson
• Publisher : Royal Society of Chemistry
• Release : 19 May 1986

Information requirements of measurement programmes; Sampling; Basic problems and aims of sampling; Time and frequency of sampling; Overall design of sampling programmes; Procedures for obtaining samples of waters; Preparation, transport, storage, and stability of samples; The nature and importance of errors in analytical results; Random error; Systematic error; Accuracy; Effects of errors on decision making; Need to estimate analytical errors; Estimation and control of the Bias of analytical results; Detailed consideration and assessment of individual sources of Bias; Assessment of

• Author : Michael E. Swartz,Ira S. Krull
• Publisher : CRC Press
• Release : 24 April 2012

Written for practitioners in both the drug and biotechnology industries, the Handbook of Analytical Validation carefully compiles current regulatory requirements on the validation of new or modified analytical methods. Shedding light on method validation from a practical standpoint, the handbook:Contains practical, up-to-date guidelines for analyti

• Author : Teresa Kowalska,Mieczyslaw Sajewicz,Joseph Sherma
• Publisher : CRC Press
• Release : 18 November 2015

Planar Chromatography–Mass Spectrometry focuses on a relatively new approach to chemical analysis in general, and to separation science in particular. It is the first book to systemically cover the theoretical background, techniques, instrumentation, and practical applications of planar chromatography–mass spectrometry as a hyphenated tool of analytical chemistry. It also examines the high and as-yet unexploited potential of planar chromatography–mass spectrometry for analytical use in scientific investigations. This book overviews the combination of planar chromatography, a relatively simple

• Author : Oana-Maria Boldura,Cornel Balta
• Publisher : BoD – Books on Demand
• Release : 12 September 2018

Electrophoresis is a widely used method in the field of life sciences, having multiple practical applications in physical, chemical, biochemical, and molecular biology domains. This book contains 8 chapters depicting various applications of this technique in biochemistry, molecular biology, and physical chemistry. This book presents the link between the exposed method and its applications in a very explicit manner and offers a wide range of practical examples. The book provides not only a vision of actual methods but also their necessary

• Author : I. Mikšík,F. Tagliaro,E. Tesarová,Z. Deyl
• Publisher : Elsevier
• Release : 28 September 1998

This book deals with chromatographic and electrophoretic methods applied for the separation (quantitation and identification) of biologically relevant compounds. It is assumed that the potential reader is familiar with the basics of chromatographic and electromigration methods. Individual separation modes are dealt with to an extent which follows their applicability for biomedical purposes: liquid chromatography and electromigration methods are therefore highlighted. Each chapter is completed with a list of recent literature covering the 1987-1997 period, which can be used for further

• Author : Serban C. Moldoveanu,Victor David
• Publisher : Newnes
• Release : 21 September 2012

This book discusses in a systematic manner the role of separation in HPLC, the types and characteristics of stationary phases and of mobile phases used in this technique, as well as other factors influencing the separation. The selection process of stationary and mobile phase for a specific separation is described as related to the physico-chemical characteristics of the molecules to be separated and of their matrix. All these subjects are discussed from the point of view of the new developments

• Author : Theodore Kuwana
• Publisher : Unknown Publisher
• Release : 19 May 1978

• Author : Xinghua Guo
• Publisher : BoD – Books on Demand
• Release : 26 February 2014

For decades gas chromatography has been and will remain an irreplaceable analytical technique in many research areas for both quantitative analysis and qualitative characterization/identification, which is still supplementary with HPLC. This book highlights a few areas where significant advances have been reported recently and/or a revisit of basic concepts is deserved. It provides an overview of instrumental developments, frontline and modern research as well as practical industrial applications. The topics include GC-based metabolomics in biomedical, plant and microbial