Single Molecule Biology

Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms of action on a molecular level as well as tracking the behaviour of molecules in living cells. This book provides the first complete and authoritative treatment of this rapidly emerging field, explicitly from a biological perspective. The contents are organized by biological system or molecule. Each chapter discusses insights that have been revealed about their mechanism, structure or function by single molecule techniques. Among the topics covered are enzymes, motor proteins, membrane channels, DNA, ribozymes, cytoskeletal proteins, and other key molecules of current interest. An introduction by the editor provides a concise review of key principles and an historical overview. The last section discusses applications in molecular diagnostics and drug discovery. * Organized by biological system or molecule. * Each chapter discusses insights into mechanism of action, structure, and function * Covers enzymes, motor proteins, membrane channels, DNA, ribozymes, etc. * Includes an introduction to key principles and an historical overview. * Discusses applications in molecular diagnostics and drug discovery. * Provides an expert's perspective on future developments.

Produk Detail:

  • Author : Alexander E. Knight
  • Publisher : Academic Press
  • Pages : 368 pages
  • ISBN : 9780080921235
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKSingle Molecule Biology

Single Molecule Biology

Single Molecule Biology
  • Author : Alexander E. Knight
  • Publisher : Academic Press
  • Release : 26 February 2009
GET THIS BOOKSingle Molecule Biology

Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms of action on a molecular level as well as tracking the behaviour of molecules in living cells. This book provides the first complete and authoritative

Biology at the Single Molecule Level

Biology at the Single Molecule Level
  • Author : S.H. Leuba,J. Zlatanova
  • Publisher : Elsevier
  • Release : 17 December 2001
GET THIS BOOKBiology at the Single Molecule Level

This is the first book solely devoted to single-molecule biochemistry and molecular biology. Authors were selected on the basis of their contribution to this new and exciting field, and were asked to focus more on the biological problems that can be approached using single-molecule techniques rather than on the techniques per se. It is thought that such techniques will eventually dominate the physical characterization of biologically important macromolecules.

Biology at the Single Molecule Level

Biology at the Single Molecule Level
  • Author : S.H. Leuba,J. Zlatanova
  • Publisher : Elsevier
  • Release : 17 December 2001
GET THIS BOOKBiology at the Single Molecule Level

This is the first book solely devoted to single-molecule biochemistry and molecular biology. Authors were selected on the basis of their contribution to this new and exciting field, and were asked to focus more on the biological problems that can be approached using single-molecule techniques rather than on the techniques per se. It is thought that such techniques will eventually dominate the physical characterization of biologically important macromolecules.

Single-Molecule Biophysics

Single-Molecule Biophysics
  • Author : Tamiki Komatsuzaki,Masaru Kawakami,Satoshi Takahashi,Haw Yang,Robert J. Silbey
  • Publisher : John Wiley & Sons
  • Release : 16 November 2011
GET THIS BOOKSingle-Molecule Biophysics

Discover the experimental and theoretical developments inoptical single-molecule spectroscopy that are changing the ways wethink about molecules and atoms The Advances in Chemical Physics series provides thechemical physics field with a forum for critical, authoritativeevaluations of advances in every area of the discipline. Thislatest volume explores the advent of optical single-moleculespectroscopy, and how atomic force microscopy has empowered novelexperiments on individual biomolecules, opening up new frontiers inmolecular and cell biology and leading to new theoreticalapproaches and insights. Organized into two

Single-molecule Techniques

Single-molecule Techniques
  • Author : Paul R. Selvin,Taekjip Ha
  • Publisher : CSHL Press
  • Release : 21 June 2021
GET THIS BOOKSingle-molecule Techniques

As molecular and cellular biologists move toward nano-techniques for performing experiments on single molecules rather than on populations of molecules, a comprehensive manual on how (and why) to carry out such experiments is needed. Single-Molecule Techniques: A Laboratory Manualfills this requirement – it is the first to take researchers who know nothing about single-molecule analyses to the point where they can successfully design and execute appropriate experiments. Geared toward research scientists in structural and molecular biology, biochemistry, and biophysics, the manual

Single Molecule Analysis

Single Molecule Analysis
  • Author : Erwin J. G. Peterman,Gijs J. L. Wuite
  • Publisher : Humana Press
  • Release : 15 September 2011
GET THIS BOOKSingle Molecule Analysis

Life scientists believe that life is driven, directed, and shaped by biomolecules working on their own or in concert. It is only in the last few decades that technological breakthroughs in sensitive fluorescence microscopy and single-molecule manipulation techniques have made it possible to observe and manipulate single biomolecules and measure their individual properties. The methodologies presented in Single Molecule Techniques: Methods and Protocols are being applied more and more to the study of biologically relevant molecules, such as DNA, DNA-binding

Biophysics of DNA-Protein Interactions

Biophysics of DNA-Protein Interactions
  • Author : Mark C. Williams,L. James Maher, III
  • Publisher : Springer Science & Business Media
  • Release : 05 October 2010
GET THIS BOOKBiophysics of DNA-Protein Interactions

Depite the rapid expansion of the field of biophysics, there are very few books that comprehensively treat specific topics in this area. Recently, the field of single molecule biophysics has developed very quickly, and a few books specifically treating single molecule methods are beginning to appear. However, the promise of single molecule biophysics is to contribute to the understanding of specific fields of biology using new methods. This book would focus on the specific topic of the biophysics of DNA-protein

Single-Molecule Science

Single-Molecule Science
  • Author : Krishnarao Appasani,Raghu Kiran Appasani
  • Publisher : Cambridge University Press
  • Release : 31 May 2021
GET THIS BOOKSingle-Molecule Science

Single Molecule Science (SMS) has emerged from developing, using and combining technologies such as super-resolution microscopy, atomic force microscopy, and optical and magnetic tweezers, alongside sophisticated computational and modelling techniques. This comprehensive, edited volume brings together authoritative overviews of these methods from a biological perspective, and highlights how they can be used to observe and track individual molecules and monitor molecular interactions in living cells. Pioneers in this fast-moving field cover topics such as single molecule optical maps, nanomachines, and

Single-molecule Studies of Proteins

Single-molecule Studies of Proteins
  • Author : Andres F. Oberhauser
  • Publisher : Springer Science & Business Media
  • Release : 09 November 2012
GET THIS BOOKSingle-molecule Studies of Proteins

In Single Molecule Studies of Proteins, expert researchers discuss the successful application of single-molecule techniques to a wide range of biological events, such as the imaging and mapping of cell surface receptors, the analysis of the unfolding and folding pathways of single proteins, the analysis interaction forces between biomolecules, the study of enzyme catalysis or the visualization of molecular motors in action. The chapters are aimed at established investigators and post-doctoral researchers in the life sciences wanting to pursue research

Single-Molecule Biophysics

Single-Molecule Biophysics
  • Author : Tamiki Komatsuzaki,Masaru Kawakami,Satoshi Takahashi,Haw Yang,Robert J. Silbey
  • Publisher : Wiley
  • Release : 16 November 2011
GET THIS BOOKSingle-Molecule Biophysics

Discover the experimental and theoretical developments in optical single-molecule spectroscopy that are changing the ways we think about molecules and atoms The Advances in Chemical Physics series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. This latest volume explores the advent of optical single-molecule spectroscopy, and how atomic force microscopy has empowered novel experiments on individual biomolecules, opening up new frontiers in molecular and cell biology and leading