Sirtuin Biology in Cancer and Metabolic Disease

Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery fills a significant void that provides a unique resource for elucidating the most recent research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entities. Scientists, physicians, students and pharmaceutical industry researchers from diverse backgrounds will use this reference as the “go-to resource for both the biology and medical applications that focus upon sirtuins. As sirtuins play an intricate role in the pathology, progression and treatment of several disease entities ranging from metabolic disease and diabetes, cancer, cardiovascular disease, immune system dysfunction, to reproductive dysfunction, and aging-related disorders, this book provides an ideal update on the topic. Details the basic and clinical role of sirtuins and their broad applicability for sirtuin biology to be targeted for multiple medical disease entities Elucidates the research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entities Summarizes the multi-discipline views and publications for this diverse topic, covering cell development, cancer and metabolism

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  • Author : Kenneth Maiese
  • Publisher : Elsevier
  • Pages : 350 pages
  • ISBN : 0128224843
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKSirtuin Biology in Cancer and Metabolic Disease

Sirtuin Biology in Cancer and Metabolic Disease

Sirtuin Biology in Cancer and Metabolic Disease
  • Author : Kenneth Maiese
  • Publisher : Elsevier
  • Release : 01 March 2021
GET THIS BOOKSirtuin Biology in Cancer and Metabolic Disease

Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery fills a significant void that provides a unique resource for elucidating the most recent research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entities. Scientists, physicians, students and pharmaceutical industry researchers from diverse backgrounds will use this reference as the “go-to resource for both the biology and medical applications

Sirtuin Biology in Medicine

Sirtuin Biology in Medicine
  • Author : Kenneth Maiese, MD
  • Publisher : Academic Press
  • Release : 15 June 2019
GET THIS BOOKSirtuin Biology in Medicine

Sirtuin Biology in Medicine: Targeting New Avenues of Care in Development, Aging, and Disease fills a significant void, providing a unique resource for elucidating the most recent research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entities. Scientists, physicians, students and pharmaceutical industry researchers from diverse backgrounds will find this book to be a go-to resource for both the biology and

Introductory Review on Sirtuins in Biology, Aging, and Disease

Introductory Review on Sirtuins in Biology, Aging, and Disease
  • Author : Leonard Guarente,Raul Mostoslavsky,Aleksey Kazantsev
  • Publisher : Academic Press
  • Release : 20 April 2018
GET THIS BOOKIntroductory Review on Sirtuins in Biology, Aging, and Disease

Introductory Review on Sirtuins in Biology and Disease provides key insights for scientists and advanced students who need to understand sirtuins and the current research in this field. This book is ideal for pharmaceutical companies as they develop novel targets using sirtuins for metabolic diseases, cancer and neurodegenerative illnesses. Sirtuins are a diverse family of proteins, with several members in mammals. The functional diversity of sirtuins is rather broad, and they have been implicated in various central biological processes. Thus,

Sirtuins in Biology and Disease

Sirtuins in Biology and Disease
  • Author : Tiago F. Outeiro,Aleksey G. Kazantsev
  • Publisher : Frontiers E-books
  • Release : 22 January 2021
GET THIS BOOKSirtuins in Biology and Disease

Sirtuins comprise a family of NAD+-dependent enzymes that have been shown to impact longevity in a number of eukaryotic organisms. Sir2 (Silent Information Regulator 2) was the first sirtuin protein discovered. The discovery that Sir2 requires NAD+ for its activity suggested a link between Sir2 activity and the phenomenon of caloric restriction in prolonging longevity. This link was strengthened by the observation that lifespan extension by caloric restriction requires Sir2 protein. Under conditions of caloric restriction, NAD+ levels are high,

Sirtuins

Sirtuins
  • Author : Riekelt H. Houtkooper
  • Publisher : Springer
  • Release : 17 November 2016
GET THIS BOOKSirtuins

The sirtuin family of proteins (SIRT1-7) received a lot of attention in recent years as they serve as metabolic sensors that control not only metabolism, but also aging and lifespan regulation. As such, sirtuins are strong targets for the treatment of age-related metabolic diseases, including obesity, diabetes, and cancer. Indeed, many research groups as well as pharmaceutical companies discovered food components and/or drugs that target the sirtuins and provide significant health benefits. This book focuses on various aspects

Introductory Review on Sirtuins in Biology, Aging, and Disease

Introductory Review on Sirtuins in Biology, Aging, and Disease
  • Author : Leonard Guarente,Raul Mostoslavsky,Aleksey Kazantsev
  • Publisher : Academic Press
  • Release : 20 April 2018
GET THIS BOOKIntroductory Review on Sirtuins in Biology, Aging, and Disease

Introductory Review on Sirtuins in Biology and Disease provides key insights for scientists and advanced students who need to understand sirtuins and the current research in this field. This book is ideal for pharmaceutical companies as they develop novel targets using sirtuins for metabolic diseases, cancer and neurodegenerative illnesses. Sirtuins are a diverse family of proteins, with several members in mammals. The functional diversity of sirtuins is rather broad, and they have been implicated in various central biological processes. Thus,

Handbook of the Biology of Aging

Handbook of the Biology of Aging
  • Author : Edward J. Masoro,Steven N. Austad
  • Publisher : Academic Press
  • Release : 13 December 2010
GET THIS BOOKHandbook of the Biology of Aging

Handbook of the Biology of Aging, Seventh Edition, reviews and synthesizes recent findings and discoveries in the field. This volume is part of The Handbooks of Aging series, which also includes The Handbook of the Psychology of Aging and The Handbook of Aging and the Social Sciences. The book is organized into two parts. Part 1 covers basic aging processes. It covers concepts relevant to clinical research, such as muscle, adipose tissue, and stem cells. It discusses research on how dietary

Resveratrol: State-of-the-art Science And Health Applications - Actionable Targets And Mechanisms Of Resveratrol

Resveratrol: State-of-the-art Science And Health Applications - Actionable Targets And Mechanisms Of Resveratrol
  • Author : Wu Joseph M,Hsieh Tze-chen
  • Publisher : World Scientific
  • Release : 06 December 2018
GET THIS BOOKResveratrol: State-of-the-art Science And Health Applications - Actionable Targets And Mechanisms Of Resveratrol

Resveratrol is a structurally simple, grape-derived polyphenol with seemingly boundless biological activities. The Editors have assembled a group of renowned scientists who have illustrious careers and lifelong passions for studies of this compound. Each chapter covers topics using published and, at times, unpublished data to provide scholarly and comprehensive reviews and perspectives. Several areas with basic clinical and public health interests are highlighted. The book is intended to serve as a text and reference covering recent research findings and clinical

Handbook of the Biology of Aging

Handbook of the Biology of Aging
  • Author : Nicolas Musi,Peter Hornsby
  • Publisher : Academic Press
  • Release : 27 January 2021
GET THIS BOOKHandbook of the Biology of Aging

Handbook of the Biology of Aging, Ninth Edition, provides a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology. The book focuses on the trend of ‘big data’ approaches in the biological sciences, presenting new strategies to analyze, interpret and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and metabolomics methodologies applied to aging related problems. Sections cover longevity pathways and interventions that modulate aging, innovative tools that

Sirtuins in Health and Disease

Sirtuins in Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 03 February 2018
GET THIS BOOKSirtuins in Health and Disease

Sirtuins in Health and Disease, Volume 154 presents the reactions catalyzed by sirtuins in terms of their unique coenzyme NAD+-dependent catalytic mechanisms, the ways to elucidate these mechanisms, and the design of the inhibitory compounds against the sirtuin-catalyzed reactions as potential therapeutic agents for human diseases. Sections cover the concepts and chemical tools in sirtuin research, SIRT4 and SIRT7, the regulatory effects of NAD metabolic pathways on sirtuin activity, sirtuins as modifiers of Huntington’s Disease (HD) pathology, parasite sirtuins

Epigenetics in Biology and Medicine

Epigenetics in Biology and Medicine
  • Author : Manel Esteller
  • Publisher : CRC Press
  • Release : 17 September 2008
GET THIS BOOKEpigenetics in Biology and Medicine

Anomalous epigenetic patterns touch many areas of study including biomedical, scientific, and industrial. With perspectives from international experts, this resource offers an all-inclusive overview of epigenetics, which bridge DNA information and function by regulating gene expression without modifying the DNA sequence itself. Epigenetics, in its

Cancer as a Metabolic Disease

Cancer as a Metabolic Disease
  • Author : Thomas Seyfried
  • Publisher : John Wiley & Sons
  • Release : 18 May 2012
GET THIS BOOKCancer as a Metabolic Disease

The book addresses controversies related to the origins of cancerand provides solutions to cancer management and prevention. Itexpands upon Otto Warburg's well-known theory that all cancer is adisease of energy metabolism. However, Warburg did not linkhis theory to the "hallmarks of cancer" and thus his theory wasdiscredited. This book aims to provide evidence, throughcase studies, that cancer is primarily a metabolic diseaserequring metabolic solutions for its management andprevention. Support for this position is derived fromcritical assessment of current cancer theories.

Histone Deacetylases: the Biology and Clinical Implication

Histone Deacetylases: the Biology and Clinical Implication
  • Author : Tso-Pang Yao,Edward Seto
  • Publisher : Springer Science & Business Media
  • Release : 31 August 2011
GET THIS BOOKHistone Deacetylases: the Biology and Clinical Implication

The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many human diseases including immune dysfunctions, heart disease, cancer, memory impairment, aging, and metabolic disorders.

Handbook of the Biology of Aging

Handbook of the Biology of Aging
  • Author : Matt Kaeberlein,George Martin
  • Publisher : Academic Press
  • Release : 20 August 2015
GET THIS BOOKHandbook of the Biology of Aging

Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of ‘big data’ approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to

Sensing in Nature

Sensing in Nature
  • Author : Carlos López-Larrea
  • Publisher : Springer Science & Business Media
  • Release : 07 March 2012
GET THIS BOOKSensing in Nature

Biological systems are an emerging discipline that may provide integrative tools by assembling the hierarchy of interactions among genes, proteins and molecular networks involved in sensory systems. The aim of this volume is to provide a picture, as complete as possible, of the current state of knowledge of sensory systems in nature. The presentation in this book lies at the intersection of evolutionary biology, cell and molecular biology, physiology and genetics. Sensing in Nature is written by a distinguished panel