Stem Cell Epigenetics

Stem Cell Epigenetics, Volume 16, examines how epigenetics are involved in stem cell differentiation, how a stem cell rapidly transitions into a molecularly distinct cell type, and how this process may be reversed or managed via epigenetic reprogramming. Topics discussed include chromatin in pluripotency, epigenetic regulation of reprogramming, stem cells and DNA methylation, histone modifications in stem cells and differentiation, higher-order chromatin conformation in pluripotent cells, epigenetics and disease modeling, organoids from pluripotent cells, transcriptional regulation in stem cells and differentiation, non-coding RNAs in pluripotency and early differentiation, and diseases caused by epigenetic alterations in stem cells. Additionally, the potential implementation of stem cell epigenetics in drug discovery, regenerative medicine, and disease treatment is discussed in detail, helping researchers and physicians bring this exciting and fast evolving field to the clinic. Provides genetic researchers, students and physicians with evidence indicating the epigenetic mechanisms involved in stem cell differentiation Highlights the specific characteristics of the epigenetic modifications and misregulations that may result in disease pathogenesis Examines the potential application of stem cell epigenetics towards developing therapeutic interventions for disease and advancing regenerative medicine Features chapter contributions by leading international experts

Produk Detail:

  • Author : Anonim
  • Publisher : Academic Press
  • Pages : 318 pages
  • ISBN : 0128140860
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKStem Cell Epigenetics

Stem Cell Epigenetics

Stem Cell Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 14 August 2020
GET THIS BOOKStem Cell Epigenetics

Stem Cell Epigenetics, Volume 16, examines how epigenetics are involved in stem cell differentiation, how a stem cell rapidly transitions into a molecularly distinct cell type, and how this process may be reversed or managed via epigenetic reprogramming. Topics discussed include chromatin in pluripotency, epigenetic regulation of reprogramming, stem cells and DNA methylation, histone modifications in stem cells and differentiation, higher-order chromatin conformation in pluripotent cells, epigenetics and disease modeling, organoids from pluripotent cells, transcriptional regulation in stem cells and differentiation,

Stem Cell Epigenetics

Stem Cell Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 13 August 2020
GET THIS BOOKStem Cell Epigenetics

Stem Cell Epigenetics, Volume 16, examines how epigenetics are involved in stem cell differentiation, how a stem cell rapidly transitions into a molecularly distinct cell type, and how this process may be reversed or managed via epigenetic reprogramming. Topics discussed include chromatin in pluripotency, epigenetic regulation of reprogramming, stem cells and DNA methylation, histone modifications in stem cells and differentiation, higher-order chromatin conformation in pluripotent cells, epigenetics and disease modeling, organoids from pluripotent cells, transcriptional regulation in stem cells and differentiation,

Epigenetic Gene Regulation in Stem Cell Differentiation and Reprogramming

Epigenetic Gene Regulation in Stem Cell Differentiation and Reprogramming
  • Author : Kevin Huang
  • Publisher : Unknown Publisher
  • Release : 24 January 2022
GET THIS BOOKEpigenetic Gene Regulation in Stem Cell Differentiation and Reprogramming

The regulatory capacities of epigenetic mechanisms including DNA methylation, histone modifications, and non-coding RNAs, have seen a rising interest in recent years. These epigenetic marks are pervasive and non-randomly distributed across the genome, raising intriguing questions on how epigenetics contributes to genomic features that define cellular identity and function. Unlike fixed genetic information that is shared between all cell types, epigenetics involve multiple layers of regulation and can vary dramatically across different cell types and genomic contexts. Thus, much more

Alterations of Epigenetics and MicroRNAs in Cancer and Cancer Stem Cell

Alterations of Epigenetics and MicroRNAs in Cancer and Cancer Stem Cell
  • Author : Yoshimasa Saito
  • Publisher : Frontiers E-books
  • Release : 10 November 2014
GET THIS BOOKAlterations of Epigenetics and MicroRNAs in Cancer and Cancer Stem Cell

Studies have shown that alterations of epigenetics and microRNAs (miRNAs) play critical roles in the initiation and progression of human cancer. Epigenetic silencing of tumor suppressor genes in cancer cells is generally mediated by DNA hypermethylation of CpG island promoter and histone modification such as methylation of histone H3 lysine 9 (H3K9) and tri-methylation of H3K27. MiRNAs are small non-coding RNAs that regulate expression of various target genes. Specific miRNAs are aberrantly expressed and play roles as tumor suppressors

Epigenetics in Human Disease

Epigenetics in Human Disease
  • Author : Trygve O. Tollefsbol
  • Publisher : Academic Press
  • Release : 24 January 2022
GET THIS BOOKEpigenetics in Human Disease

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable,

Pluripotent Stem Cells

Pluripotent Stem Cells
  • Author : Deepa Bhartiya,Nibedita Lenka
  • Publisher : BoD – Books on Demand
  • Release : 28 August 2013
GET THIS BOOKPluripotent Stem Cells

Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown

Stem Cells in Development and Disease

Stem Cells in Development and Disease
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 30 June 2004
GET THIS BOOKStem Cells in Development and Disease

This volume of Current Topics in Developmental Biology showcases the research and therapeutic value of stem cells, and is proof of the increasing maturation of the fields of regenerative and molecular medicine. Reviews include: * Therapeutic cloning and tissue engineering to produce functional replacement tissues. * The role of the protein a-synuclein in a host of neurodegenerative diseases, which may be the first to benefit from stem cell therapy. * The curious array of functions in eukaryotic DNA methyltransferase, crucial for normal development

Human Embryonic Stem Cells

Human Embryonic Stem Cells
  • Author : Arlene Chiu,Mahendra S. Rao
  • Publisher : Springer Science & Business Media
  • Release : 01 August 2003
GET THIS BOOKHuman Embryonic Stem Cells

A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem

Single Cell High Content Textural Image Analysis of Dynamic Epigenetic Signatures as a Response to Defined Microenvironmental Parameters

Single Cell High Content Textural Image Analysis of Dynamic Epigenetic Signatures as a Response to Defined Microenvironmental Parameters
  • Author : Joseph Jung-Woong Kim
  • Publisher : Unknown Publisher
  • Release : 24 January 2022
GET THIS BOOKSingle Cell High Content Textural Image Analysis of Dynamic Epigenetic Signatures as a Response to Defined Microenvironmental Parameters

Currently, quantifiable investigations of the epigenome require cell lysis and are population based, prohibiting direct investigations of intact intranuclear structural organization and introducing noise into data obtained from inherently heterogeneous stem cell populations. To address this, we have developed and employed a single-cell high-content image informatics framework to capture organizational signatures of epigenetic signaling components from images of cellular nuclei obtained via superresolution nanoscopy. High dimensional quantitative texture descriptors of the organizational dynamics of key posttranslational modifications to core histone

Epigenetics and Regeneration

Epigenetics and Regeneration
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 24 May 2019
GET THIS BOOKEpigenetics and Regeneration

Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing

Epigenetic Mechanisms in Cellular Reprogramming

Epigenetic Mechanisms in Cellular Reprogramming
  • Author : Alexander Meissner,Jörn Walter
  • Publisher : Springer
  • Release : 11 December 2014
GET THIS BOOKEpigenetic Mechanisms in Cellular Reprogramming

The ability of a single genome to give rise to hundreds of functionally distinct cell type programs is in itself remarkable. Pioneering studies over the past few decades have demonstrated that this plasticity is retained throughout development, a phenomenon of epigenetic programming and reprogramming that remains one of the most fascinating areas of modern biology, with major relevance to human health and disease. This book presents the basic biology involved, including key mechanistic insights into this rapidly growing field.

Stem Cell Proliferation and Differentiation

Stem Cell Proliferation and Differentiation
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 24 March 2020
GET THIS BOOKStem Cell Proliferation and Differentiation

Stem Cell Proliferation and Differentiation, Volume 138, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series Includes the latest information on stem cell proliferation and differentiation

Stem Cell Genetics for Biomedical Research

Stem Cell Genetics for Biomedical Research
  • Author : Raul Delgado-Morales
  • Publisher : Springer
  • Release : 27 June 2018
GET THIS BOOKStem Cell Genetics for Biomedical Research

This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer’s disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together

Handbook of Epigenetics

Handbook of Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release : 10 July 2017
GET THIS BOOKHandbook of Epigenetics

Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue

Epigenetics

Epigenetics
  • Author : Lyle Armstrong
  • Publisher : Garland Pub
  • Release : 24 January 2022
GET THIS BOOKEpigenetics

"The concept of epigenetics has been known about since the 1940s, but it is only in the last 10 years that research has shown just how wide ranging its effects are. It is now a very widely-used term, but there is still a lot of confusion surrounding what it actually is and does. Epigenetics brings together the structure and machinery of epigenetic modification, how epigenetic modification controls cellular functions, and the evidence for the relationship between epigenetics and disease. It will