Stem Cell Manufacturing

Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives is expected to have a positive impact in the society since it will contribute to widen the offer of therapeutic solutions to the patients. Fully defined cellular products can be used to restore the structure and function of damaged tissues and organs and to develop stem cell-based cellular therapies for the treatment of cancer and hematological disorders, autoimmune and other inflammatory diseases and genetic disorders. Presents the first ‘Flowchart‘ of stem cell manufacturing enabling easy understanding of the various processes in a sequential and coherent manner Covers all bioprocess technologies required for the transfer of the bench findings to the clinic including the process components: cell signals, bioreactors, modeling, automation, safety, etc. Presents comprehensive coverage of a true multidisciplinary topic by bringing together specialists in their particular area Provides the basics of the processes and identifies the issues to be resolved for large scale cell culture by the bioengineer Addresses the critical need in bioprocessing for the successful delivery of stem cell technology to the market place by involving professional engineers in sections of the book

Produk Detail:

  • Author : Joaquim M. S. Cabral
  • Publisher : Elsevier
  • Pages : 340 pages
  • ISBN : 0444632662
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKStem Cell Manufacturing

Stem Cell Manufacturing

Stem Cell Manufacturing
  • Author : Joaquim M. S. Cabral,Claudia Lobato da Silva,Lucas G. Chase,Maria Margarida Diogo
  • Publisher : Elsevier
  • Release : 24 July 2016
GET THIS BOOKStem Cell Manufacturing

Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives

Stem Cell Manufacturing

Stem Cell Manufacturing
  • Author : Joaquim M. S. Cabral
  • Publisher : Elsevier
  • Release : 25 July 2016
GET THIS BOOKStem Cell Manufacturing

Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives

Novel Perspectives of Stem Cell Manufacturing and Therapies

Novel Perspectives of Stem Cell Manufacturing and Therapies
  • Author : Diana Kitala,Ana Colette Maurício
  • Publisher : BoD – Books on Demand
  • Release : 14 April 2021
GET THIS BOOKNovel Perspectives of Stem Cell Manufacturing and Therapies

In the 1950s, Nobel Prize winner Dr. E. Donnall Thomas was the first to successfully transplant hematopoietic stem cells. Since then, studies on stem cells have evolved and expanded worldwide. There are more than 650,000 scientific publications on stem cells and more than 8000 stem cell clinical trials. This book summarizes types of stem cells, key studies, ongoing trials, and future perspectives. It also includes ethical, formal, and legal aspects to give the reader a comprehensive view of the field.

Stem Cells and Good Manufacturing Practices

Stem Cells and Good Manufacturing Practices
  • Author : Kursad Turksen
  • Publisher : Humana
  • Release : 01 April 2021
GET THIS BOOKStem Cells and Good Manufacturing Practices

This detailed book explores the utilization and delivery of stem cells for therapeutic purposes in patients in the clinic and the tightly controlled Good Manufacturing Practices (GMP) that make these powerful techniques possible. Fully updated and expanded from the first edition, this collection features a new set of protocols to arm stem cell biologists with protocols that are currently being used in a number of well-established facilities around the world. Written for the highly successful Methods in Molecular Biology series,

Stem Cell Bioprocessing

Stem Cell Bioprocessing
  • Author : Tiago G Fernandes,Maria Margarida Diogo,Joaquim M. S. Cabral
  • Publisher : Elsevier
  • Release : 15 November 2013
GET THIS BOOKStem Cell Bioprocessing

Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different

Stem Cells and Good Manufacturing Practices

Stem Cells and Good Manufacturing Practices
  • Author : Kursad Turksen
  • Publisher : Humana Press
  • Release : 14 February 2015
GET THIS BOOKStem Cells and Good Manufacturing Practices

This volume collects a series of protocols describing the kinds of infrastructures, training, and standard operating procedures currently available to actualize the potential of stem cells for regenerative therapies. Stem Cells and Good Manufacturing Practices: Methods, Protocols, and Regulations pulls together key GMP techniques from laboratories around the world. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on

Progress in Stem Cell Transplantation

Progress in Stem Cell Transplantation
  • Author : Taner Demirer
  • Publisher : BoD – Books on Demand
  • Release : 02 December 2015
GET THIS BOOKProgress in Stem Cell Transplantation

This book documents the increased amount of stem cell-related research, basic and clinical applications as well as views for the future. The book covers a wide range of issues related to new developments and innovations in cell-based therapies discussed in basic and clinical chapters from authors around the world involved in stem cell studies and research. It thereby complements and extends the basic coverage of stem cells, such as mesenchymal stem cells, effect of stem cells on aging, cover hematopoietic

Mesenchymal Stem Cell Manufacturing for Clinical Use

Mesenchymal Stem Cell Manufacturing for Clinical Use
  • Author : Franca Fagioli
  • Publisher : Unknown Publisher
  • Release : 22 September 2021
GET THIS BOOKMesenchymal Stem Cell Manufacturing for Clinical Use

Mesenchymal stromal/stem cells (MSCs) are adult, self-renewable, multipotent cells that can be isolated in various tissues, most commonly bone marrow (BM) and adipose tissue. Because of their capacity for self-renewal and differentiation into tissues of mesodermal origin and due to their immunomodulatory ability, MSCs are used in many preclinical and clinical studies as possible new therapeutic agents for the treatment of a very broad range of conditions, including heart, hepatic, and neurodegenerative diseases.

Stem Cells and Cell Therapy

Stem Cells and Cell Therapy
  • Author : Mohamed Al-Rubeai,Mariam Naciri
  • Publisher : Springer Science & Business Media
  • Release : 01 October 2013
GET THIS BOOKStem Cells and Cell Therapy

With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating

Stem Cells in Clinical Practice and Tissue Engineering

Stem Cells in Clinical Practice and Tissue Engineering
  • Author : Rakesh Sharma
  • Publisher : BoD – Books on Demand
  • Release : 02 May 2018
GET THIS BOOKStem Cells in Clinical Practice and Tissue Engineering

Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters

Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
  • Author : Lucas G. Chase,Mohan C Vemuri
  • Publisher : Springer Science & Business Media
  • Release : 12 December 2012
GET THIS BOOKMesenchymal Stem Cell Therapy

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host

Cell Therapy

Cell Therapy
  • Author : Adrian Gee
  • Publisher : Springer Science & Business Media
  • Release : 18 September 2009
GET THIS BOOKCell Therapy

Cell Therapy: cGMP Facilities and Manufacturing is the source for a complete discussion of facility design and operation with practical approaches to a variety of day-to-day activities, such as staff training and competency, cleaning procedures, and environmental monitoring. This in-depth book also includes detailed reviews of quality, the framework of regulations, and professional standards. It meets a previously unmet need for a thorough facility-focused resource, Cell Therapy: cGMP Facilities and Manufacturing will be an important addition to the cell therapy

Stem Cell Bioprocessing and Manufacturing

Stem Cell Bioprocessing and Manufacturing
  • Author : Joaquim M. S. Cabral,Cláudia Lobato da Silva,Maria Margarida Diogo
  • Publisher : MDPI
  • Release : 20 January 2021
GET THIS BOOKStem Cell Bioprocessing and Manufacturing

The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. However, whilst science has revealed the potential, and early products have shown the power of such therapies, there is an immediate and long-term need for expertise with the necessary skills to face the engineering and life

Perinatal Stem Cells

Perinatal Stem Cells
  • Author : Zhong Chao Han,Tsuneo A. Takahashi,Zhibo Han,Zongjin Li
  • Publisher : Springer
  • Release : 06 April 2019
GET THIS BOOKPerinatal Stem Cells

This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury. Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be cultured indefinitely ex vivo, and can differentiate into three germ layers, ethical issues, the teratoma formation of ESCs and

Mesenchymal Stromal Cells

Mesenchymal Stromal Cells
  • Author : Hematti Peiman,Sowmya Viswanathan
  • Publisher : Academic Press
  • Release : 11 August 2016
GET THIS BOOKMesenchymal Stromal Cells

Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique book covers the development and production of clinical-grade products that are suitable for use in humans. From design of a cell production facility, to obtaining regulatory approval and reimbursement issues,