The Brain and Host Defense

It is now well recognized that the brain, and especially the hypothalamus, plays an important role in the regulation of immune reactions and inflammation. This book aims to review our current state of knowledge of this important field. Key historical findings are presented, and the reciprocal interactions between the brain and the immune system are examined. Particular emphasis is placed on inflammation, a critical host defense reaction that serves as an effector response for both the adaptive and innate immune systems. Mechanisms implicated in brain defense, as well as in more general host defense, are discussed. The regulatory influences of the brain on inflammatory responses are included with particular reference to the role of the hypothalamus, which is also the main director the hormonal regulation of immune/inflammatory. Gender-related differences in immune responsiveness, circadian modulator of immune responses, and evidence that behavioral conditioning (e.g. reward) of immune responses is possible are used as examples to reinforce the notion that the neuroendocrine system exerts a fundamental and complex regulatory influence on the immune system. * Presents timely issues such as immunological aspects of the blood-brain-barrier and the role of inflammatory mediators in the evolution of strokes and degenerative diseases * Includes analysis of the role of the brain in the adaptive responses to disease * Evaluates the argument that further knowledge of the influence of the brain on the immune system will provide new insights to the pathophysiology infectious and autoimmune diseases

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  • Author : Anonim
  • Publisher : Elsevier
  • Pages : 358 pages
  • ISBN : 9780444535450
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKThe Brain and Host Defense

The Brain and Host Defense

The Brain and Host Defense
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 24 December 2009
GET THIS BOOKThe Brain and Host Defense

It is now well recognized that the brain, and especially the hypothalamus, plays an important role in the regulation of immune reactions and inflammation. This book aims to review our current state of knowledge of this important field. Key historical findings are presented, and the reciprocal interactions between the brain and the immune system are examined. Particular emphasis is placed on inflammation, a critical host defense reaction that serves as an effector response for both the adaptive and innate immune

Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity

Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity
  • Author : C. Jane Welsh,Mary Meagher,Esther Sternberg
  • Publisher : Springer Science & Business Media
  • Release : 05 April 2007
GET THIS BOOKNeural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity

This book provides a lucid summary of behavioral, neural and endocrine regulation of immune responses and of the effects of immune system activity on neural and endocrine functions and behavior. The underlying premise is that the brain and immune system represent a single, integrated system of defense. The discussion includes such topics and stress induced modulation of innate resistance and adaptive immunity in influenza viral infections.

Differential Roles for the CXC Chemokine Receptors in Host Defense and Disease Following Viral Infection of the Central Nervous System

Differential Roles for the CXC Chemokine Receptors in Host Defense and Disease Following Viral Infection of the Central Nervous System
  • Author : Martin Philip Hosking
  • Publisher : Unknown Publisher
  • Release : 20 January 2022
GET THIS BOOKDifferential Roles for the CXC Chemokine Receptors in Host Defense and Disease Following Viral Infection of the Central Nervous System

Using neutralizing antibodies, we assessed the roles for the CXC chemokine receptors CXCR3 and CXCR2 during acute and chronic viral encephalomyelitis. Previous work in our laboratory has identified CXCR3 ligands as critical mediators of both host defense during acute infection and demyelination during chronic infection. The precise role for CXCR3 in attracting activated T lymphocytes was however unclear. We observed constitutive expression of CXCR3 upon both subsets of T cells during acute and chronic infection. Neutralization of CXCR3 during acute

Host Defense Dysfunction in Trauma, Shock and Sepsis

Host Defense Dysfunction in Trauma, Shock and Sepsis
  • Author : Eugen Faist,Jonathan L. Meakins,Friedrich W. Schildberg
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKHost Defense Dysfunction in Trauma, Shock and Sepsis

This book presents a unique overview of all aspects of host defense alterations under stressful conditions. It is based on the most important contributions given at the "2nd International Congress on the Immune Consequences of Trauma, Shock, and Sepsis-Mechanisms and Therapeutic Approaches," which was held in Munich under the auspices of the most distinguished scientific societies involved in this field (Society of Critical Care Medicine, European Society of Intensive Care Medicine, Societe Internationale de Chirurgie, Surgical Infection Society, Surgical Infection

Characterization of Intracellular Group B Streptococcus and Host Defense

Characterization of Intracellular Group B Streptococcus and Host Defense
  • Author : Andrew Scott Cutting
  • Publisher : Unknown Publisher
  • Release : 20 January 2022
GET THIS BOOKCharacterization of Intracellular Group B Streptococcus and Host Defense

Bacterial meningitis is a severe, life threatening concern, which results in a high proportion of patients succumbing to disease. There are limited treatments available for this disease and individuals that survive endure an immense amount of outstanding consequences for the remainder of their lives. An important causative agent of bacterial meningitis is the human pathogen Streptococcus agalactiae, also known as Group B Streptococcus (GBS). GBS is known to be the leading cause of neonatal sepsis and meningitis thereby resulting in

Host Defense and Infection

Host Defense and Infection
  • Author : Labro
  • Publisher : CRC Press
  • Release : 12 July 1994
GET THIS BOOKHost Defense and Infection

Spotlighting the recent development of antimicrobial molecules with immunomodulatory properties, this unique reference presents a detailed description of natural antimicrobial host defenses and elucidates how anti-infectious agents modulate the various effectors involved in combating environmental pathogens Reveals how Cefodizime (the only antibacterial drug to modulate the immune system in multiple ways) restores some impaired defense systems of the body, complementing its antibiotic activity. Investigating the biochemical interactions between antimicrobial agents and the immune system, Host Defense and Infection discusses innate

Insights to Neuroimmune Biology

Insights to Neuroimmune Biology
  • Author : Istvan Berczi
  • Publisher : Elsevier
  • Release : 03 February 2016
GET THIS BOOKInsights to Neuroimmune Biology

Insights to Neuroimmune Biology, Second Edition discusses the systemic regulatory network, coordination, organization, and interpretation of the rapidly accumulating knowledge on the topic of neuroimmune biology, with an ultimate goal of helping readers understand the function of higher organisms, including man, in their entire complexity. This publication provides assessments and interpretations of accumulated experimental evidence, enabling the scientific community to keep abreast of essential advancements of existing knowledge as we search for greater understanding of the biology of higher organisms.

Sleep Deprivation

Sleep Deprivation
  • Author : Clete A. Kushida
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOKSleep Deprivation

Analyzing ground-breaking research, this reference highlights the impact of sleep deprivation on the well-being of the individual and society-presenting current theories on the function of sleep, the effects of sleep deprivation on patients with medical and psychiatric conditions, as well as providing interpretative and methodological results in comparative studies of sleep deprivation.

New Insights to Neuroimmune Biology

New Insights to Neuroimmune Biology
  • Author : Istvan Berczi
  • Publisher : Elsevier
  • Release : 27 May 2010
GET THIS BOOKNew Insights to Neuroimmune Biology

New Insights to Neuroimmune Biology investigates the mechanisms that and functions of the Neuroimmune Regulatory Supersystem. Covering molecular regulation of cytokines in brain astrocytes, immunoregulation by the sympathetic nervous system, circadian regulation of immune reactions, antigen recognition by the CNS, the modulation of the immune response by head injury, neurogenic inflammation, the role of tachykinins in asthma and allergic disease, defence and defeat reactions, cytokines, behavior and affective disorders, increased activity of type 1 helper T cell functions after reward stimulation.

The Cellular Basis of Central Nervous System HIV-1 Infection and the AIDS Dementia Complex

The Cellular Basis of Central Nervous System HIV-1 Infection and the AIDS Dementia Complex
  • Author : Richard W Price,John J Sidtis
  • Publisher : Routledge
  • Release : 12 May 2014
GET THIS BOOKThe Cellular Basis of Central Nervous System HIV-1 Infection and the AIDS Dementia Complex

In this exciting symposium, the editor brings to print important new information on AIDS and how HIV affects the brain. Each chapter focuses on one or more of the cell types that reside in or traffic through the central nervous system (CNS). Each of these cells is important to considerations of the pathogenesis of the CNS. Neurologists, AIDS physicians, and other professionals caring for AIDS patients will find that this “cell-based” view provides a unique perspective and that it will

Neuroimmunology of Sleep

Neuroimmunology of Sleep
  • Author : S. R. Pandi-Perumal,Daniel P. Cardinali,Georgios Chrousos
  • Publisher : Springer Science & Business Media
  • Release : 19 August 2007
GET THIS BOOKNeuroimmunology of Sleep

This timely work reflects the growing importance of research into the nature of sleep and its medical aspects. One of the first of its kind, this work on the neuroimmunology of sleep provides an introduction to the interplay between these two key and interlinked areas. Written both from a basic and a clinical perspective, the volume is an invaluable information resource for biomedical professionals and students of the human biology. Highly practical guide written from both a basic and clinical

Principles and Practice of Sleep Medicine E-Book

Principles and Practice of Sleep Medicine E-Book
  • Author : Meir H. Kryger,Thomas Roth,William C. Dement
  • Publisher : Elsevier Health Sciences
  • Release : 01 November 2010
GET THIS BOOKPrinciples and Practice of Sleep Medicine E-Book

Principles and Practice of Sleep Medicine, 5th Edition, by Meir H. Kryger, MD, FRCPC, Thomas Roth, PhD, and William C. Dement, MD, PhD, delivers the comprehensive, dependable guidance you need to effectively diagnose and manage even the most challenging sleep disorders. Updates to genetics and circadian rhythms, occupational health, sleep in older people, memory and sleep, physical examination of the patient, comorbid insomnias, and much more keep you current on the newest areas of the field. A greater emphasis on