The Cellular Secretome and Organ Crosstalk

The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health and disease. Communication between different organs involves lipids and other small molecules and a host of proteins and peptides comprising the secretome of different organs (organokinome). More than 600 adipokines have been identified, and an increasing number of hepatokines and myokines have recently been discovered with mostly unknown physiological impact. Importantly, an aberrant signature of the organokinome may be critically underlying a variety of metabolic diseases and may determine the individual susceptibility to disease development. Summarizes our current knowledge on the secretome of different cells and tissues Dissects auto-, para- and endocrine functions of major secreted peptides and proteins Analyzes the secretory malfunction of different cells and its impact for disease development Authored by a leader in the field, presenting a coherent view on this very complex topic

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  • Author : Juergen Eckel
  • Publisher : Academic Press
  • Pages : 240 pages
  • ISBN : 0128097191
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKThe Cellular Secretome and Organ Crosstalk

The Cellular Secretome and Organ Crosstalk

The Cellular Secretome and Organ Crosstalk
  • Author : Juergen Eckel
  • Publisher : Academic Press
  • Release : 12 June 2018
GET THIS BOOKThe Cellular Secretome and Organ Crosstalk

The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health

Scientific Principles of Adipose Stem Cells

Scientific Principles of Adipose Stem Cells
  • Author : Lauren Kokai,Kacey Marra,J. Peter Rubin
  • Publisher : Academic Press
  • Release : 01 September 2021
GET THIS BOOKScientific Principles of Adipose Stem Cells

Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype.

Mechanisms of Insulin Action

Mechanisms of Insulin Action
  • Author : Alan R. Saltiel,Jeffrey E. Pessin
  • Publisher : Springer Science & Business Media
  • Release : 05 October 2007
GET THIS BOOKMechanisms of Insulin Action

More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.

The Biology and Therapeutic Application of Mesenchymal Cells - Set

The Biology and Therapeutic Application of Mesenchymal Cells - Set
  • Author : Kerry Atkinson
  • Publisher : John Wiley & Sons
  • Release : 17 January 2017
GET THIS BOOKThe Biology and Therapeutic Application of Mesenchymal Cells - Set

The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited,

Control of Energy Metabolism

Control of Energy Metabolism
  • Author : Britton Chance,Ronald W. Estabrook,John R. Williamson
  • Publisher : Academic Press
  • Release : 12 May 2014
GET THIS BOOKControl of Energy Metabolism

Control of Energy Metabolism: A Colloquium of the Johnson Research Foundation focuses on the processes, reactions, and approaches involved in the control of energy metabolism. The selection first offers information on the respiratory chain as a model for metabolic control in multi-enzyme systems, dynamics and control in cellular reactions, and computer-based analysis of biochemical data. The text then explores purification and properties of rabbit skeletal muscle phosphofructokinase; multiple forms of heart phosphofructokinase; and mechanisms of inhibition and activation of phosphofructokinase

Muscle and Exercise Physiology

Muscle and Exercise Physiology
  • Author : Jerzy A. Zoladz
  • Publisher : Academic Press
  • Release : 05 November 2018
GET THIS BOOKMuscle and Exercise Physiology

Muscle and Exercise Physiology is a comprehensive reference covering muscle and exercise physiology, from basic science to advanced knowledge, including muscle power generating capabilities, muscle energetics, fatigue, aging and the cardio-respiratory system in exercise performance. Topics presented include the clinical importance of body responses to physical exercise, including its impact on oxygen species production, body immune system, lipid and carbohydrate metabolism, cardiac energetics and its functional reserves, and the health-related effects of physical activity and inactivity. Novel topics like critical

A New Component of Skeletal Muscle Secretome Impact on Beta Cells and Prevent TNF-a and Cytomix Effect on Beta-cells

A New Component of Skeletal Muscle Secretome Impact on Beta Cells and Prevent TNF-a and Cytomix Effect on Beta-cells
  • Author : Bouzakri Karim
  • Publisher : Unknown Publisher
  • Release : 22 January 2022
GET THIS BOOKA New Component of Skeletal Muscle Secretome Impact on Beta Cells and Prevent TNF-a and Cytomix Effect on Beta-cells

A new positive component of skeletal muscle secretome impact on beta cells and prevent TNF-alpha and cytomix effect on beta cells.Karim Bouzakri, Julien Cherfan, Harzo Hamdard, Carole Mura, Claude Peronet, and Michel Pinget.UMR DIATHEC, EA 7294, Centre Europu00e9en du2019Etude du Diabu00e8te, Universitu00e9 de Strasbourg (UdS), Boulevard Renu00e9 Leriche 67200 Strasbourg, FranceBackground and aims: Inter-organ crosstalk including possible communication between skeletal muscle and beta cells is an important component of normal physiology that may

Lung Stem Cells in Development, Health and Disease

Lung Stem Cells in Development, Health and Disease
  • Author : Nikolic, Marko Z.,Hogan, Brigid L.M.
  • Publisher : European Respiratory Society
  • Release : 01 April 2021
GET THIS BOOKLung Stem Cells in Development, Health and Disease

Most organs in the adult human body are able to maintain themselves and undergo repair after injury; these processes are largely dependent on stem cells. In this Monograph, the Guest Editors bring together leading authors in the field to provide information about the different classes of stem cells present both in the developing and adult lung: where they are found, how they function in homeostasis and pathologic conditions, the mechanisms that regulate their behaviour, and how they may be harnessed

Physics of Cancer

Physics of Cancer
  • Author : Claudia Mierke
  • Publisher : Iop Publishing Limited
  • Release : 22 September 2015
GET THIS BOOKPhysics of Cancer

'Physics of Cancer' emphasizes a novel biophysical-based view on cancer disease and metastasis highlighting the functional role of mechanical properties of cells while describing the biological state of cancer. Originating in part from the author's own courses on tumor biology and cellular biophysics, this book is suitable for students and researchers in this dynamic interdisciplinary field, be they from a physical, biological or medical sciences background.

Adipose Tissue Biology

Adipose Tissue Biology
  • Author : Michael E. Symonds
  • Publisher : Springer
  • Release : 03 April 2017
GET THIS BOOKAdipose Tissue Biology

The past decade has seen an exponential increase in our knowledge and understanding of adipose tissue biology. This has coincided with the continued rise in obesity across all generations. Clearly despite substantial advances in research into adipose tissue this still has had limited impact on the on-going obesity epidemic across a majority of countries in the world. This book brings together many leading experts in the field to provide an up to date and comprehensive review of the key aspects

Nutrition in the Prevention and Treatment of Abdominal Obesity

Nutrition in the Prevention and Treatment of Abdominal Obesity
  • Author : Ronald Ross Watson
  • Publisher : Elsevier
  • Release : 26 February 2014
GET THIS BOOKNutrition in the Prevention and Treatment of Abdominal Obesity

Nutrition in the Prevention and Treatment of Abdominal Obesity focuses on the important roles that exercise, dietary changes, and foods play in promoting as well as reducing visceral fat. Nutritionists, dieticians, and healthcare providers seeking to address the abdominal obesity epidemic will use this comprehensive resource as a tool in their long-term goal of preventing chronic diseases, especially heart, vascular, and diabetic diseases. Experts from a broad range of disciplines are involved in dealing with the consequences of excessive abdominal

Translational Inflammation

Translational Inflammation
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 24 November 2018
GET THIS BOOKTranslational Inflammation

Translational Inflammation links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming a valuable tool in both direct treatment and the development of therapeutics. Translational Inflammation, the 4th volume in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. Emphasizes