The Cellular Secretome and Organ Crosstalk

The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health and disease. Communication between different organs involves lipids and other small molecules and a host of proteins and peptides comprising the secretome of different organs (organokinome). More than 600 adipokines have been identified, and an increasing number of hepatokines and myokines have recently been discovered with mostly unknown physiological impact. Importantly, an aberrant signature of the organokinome may be critically underlying a variety of metabolic diseases and may determine the individual susceptibility to disease development. Summarizes our current knowledge on the secretome of different cells and tissues Dissects auto-, para- and endocrine functions of major secreted peptides and proteins Analyzes the secretory malfunction of different cells and its impact for disease development Authored by a leader in the field, presenting a coherent view on this very complex topic

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  • Author : Juergen Eckel
  • Publisher : Academic Press
  • Pages : 240 pages
  • ISBN : 0128097191
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKThe Cellular Secretome and Organ Crosstalk

The Cellular Secretome and Organ Crosstalk

The Cellular Secretome and Organ Crosstalk
  • Author : Juergen Eckel
  • Publisher : Academic Press
  • Release : 12 June 2018
GET THIS BOOKThe Cellular Secretome and Organ Crosstalk

The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health

Scientific Principles of Adipose Stem Cells

Scientific Principles of Adipose Stem Cells
  • Author : Lauren Kokai,Kacey Marra,J. Peter Rubin
  • Publisher : Academic Press
  • Release : 01 September 2021
GET THIS BOOKScientific Principles of Adipose Stem Cells

Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype.

The Biology and Therapeutic Application of Mesenchymal Cells - Set

The Biology and Therapeutic Application of Mesenchymal Cells - Set
  • Author : Kerry Atkinson
  • Publisher : John Wiley & Sons
  • Release : 17 January 2017
GET THIS BOOKThe Biology and Therapeutic Application of Mesenchymal Cells - Set

The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited,

Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
  • Author : Lucas G. Chase,Mohan C Vemuri
  • Publisher : Springer Science & Business Media
  • Release : 12 December 2012
GET THIS BOOKMesenchymal Stem Cell Therapy

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host

A New Component of Skeletal Muscle Secretome Impact on Beta Cells and Prevent TNF-a and Cytomix Effect on Beta-cells

A New Component of Skeletal Muscle Secretome Impact on Beta Cells and Prevent TNF-a and Cytomix Effect on Beta-cells
  • Author : Bouzakri Karim
  • Publisher : Unknown Publisher
  • Release : 20 September 2021
GET THIS BOOKA New Component of Skeletal Muscle Secretome Impact on Beta Cells and Prevent TNF-a and Cytomix Effect on Beta-cells

A new positive component of skeletal muscle secretome impact on beta cells and prevent TNF-alpha and cytomix effect on beta cells.Karim Bouzakri, Julien Cherfan, Harzo Hamdard, Carole Mura, Claude Peronet, and Michel Pinget.UMR DIATHEC, EA 7294, Centre Europu00e9en du2019Etude du Diabu00e8te, Universitu00e9 de Strasbourg (UdS), Boulevard Renu00e9 Leriche 67200 Strasbourg, FranceBackground and aims: Inter-organ crosstalk including possible communication between skeletal muscle and beta cells is an important component of normal physiology that may

Mechanisms of Adiponectin Action

Mechanisms of Adiponectin Action
  • Author : Tania Fiaschi
  • Publisher : MDPI
  • Release : 26 July 2019
GET THIS BOOKMechanisms of Adiponectin Action

The adipokine adiponectin is very concentrated in plasma, and decreased levels of adiponectin are associated with pathological conditions such as obesity, diabetes, cardiovascular diseases, and metabolic syndrome. When produced in its full-length form, adiponectin self-associates to generate multimeric complexes. The full-length form of adiponectin can be cleaved by the globular form of elastase that is produced locally, and the resulting biological effects are exerted in a paracrine or autocrine manner. The different forms of adiponectin bind to specific receptors consisting

Nutrition in the Prevention and Treatment of Abdominal Obesity

Nutrition in the Prevention and Treatment of Abdominal Obesity
  • Author : Ronald Ross Watson
  • Publisher : Elsevier
  • Release : 26 February 2014
GET THIS BOOKNutrition in the Prevention and Treatment of Abdominal Obesity

Nutrition in the Prevention and Treatment of Abdominal Obesity focuses on the important roles that exercise, dietary changes, and foods play in promoting as well as reducing visceral fat. Nutritionists, dieticians, and healthcare providers seeking to address the abdominal obesity epidemic will use this comprehensive resource as a tool in their long-term goal of preventing chronic diseases, especially heart, vascular, and diabetic diseases. Experts from a broad range of disciplines are involved in dealing with the consequences of excessive abdominal

Advanced Techniques in Bone Regeneration

Advanced Techniques in Bone Regeneration
  • Author : Alessandro Rozim Zorzi,João Batista de Miranda
  • Publisher : BoD – Books on Demand
  • Release : 31 August 2016
GET THIS BOOKAdvanced Techniques in Bone Regeneration

Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering. This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.

Adipose Tissue Biology

Adipose Tissue Biology
  • Author : Michael E. Symonds
  • Publisher : Springer
  • Release : 03 April 2017
GET THIS BOOKAdipose Tissue Biology

The past decade has seen an exponential increase in our knowledge and understanding of adipose tissue biology. This has coincided with the continued rise in obesity across all generations. Clearly despite substantial advances in research into adipose tissue this still has had limited impact on the on-going obesity epidemic across a majority of countries in the world. This book brings together many leading experts in the field to provide an up to date and comprehensive review of the key aspects

Cardiotoxicity

Cardiotoxicity
  • Author : Wenyong Tan
  • Publisher : BoD – Books on Demand
  • Release : 14 November 2018
GET THIS BOOKCardiotoxicity

Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well

Crosstalk between the osteogenic and neurogenic stem cell niches: how far are they from each other?

Crosstalk between the osteogenic and neurogenic stem cell niches: how far are they from each other?
  • Author : Wanda Lattanzi,Maria Concetta Geloso
  • Publisher : Frontiers Media SA
  • Release : 14 March 2016
GET THIS BOOKCrosstalk between the osteogenic and neurogenic stem cell niches: how far are they from each other?

Somatic stem cells reside in definite compartments, known as "niches", within developed organs and tissues, being able to renew themselves, differentiate and ensure tissue maintenance and repair. In contrast with the original dogmatic distinction between renewing and non-renewing tissues, somatic stem cells have been found in almost every human organism, including brain and heart. (HSCs) and mesenchymal stem cells (MSCs), that intensely interacts. HSCs represent the common precursors of all mature blood cells. (Bone, cartilage, blood vessels, adipose tissue, and.),

Pericyte Biology in Different Organs

Pericyte Biology in Different Organs
  • Author : Alexander Birbrair
  • Publisher : Springer
  • Release : 01 April 2019
GET THIS BOOKPericyte Biology in Different Organs

The present book is an attempt to describe the most recent developments in the area of pericyte biology which is one of the emergent hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of thirteen detailed chapters on what we know so far about pericytes in distinct organs in physiological and pathological conditions. Further, it provides an update on the most novel functions attributed to these cells and will introduce a newer

Stem Cell Drugs - A New Generation of Biopharmaceuticals

Stem Cell Drugs - A New Generation of Biopharmaceuticals
  • Author : Phuc Van Pham
  • Publisher : Springer
  • Release : 25 October 2018
GET THIS BOOKStem Cell Drugs - A New Generation of Biopharmaceuticals

This invaluable resource discusses the current revolution in stem cell-based drugs and their potential use in clinical applications. Each chapter is contributed by a pre-eminent scientist in the field. An introductory section presents current stem cell drugs and stem cell-based products and a discussion of production, quality control, mechanisms, and efficacy. Following sections include discussions on stem cell-derived microvesicles based products, and derived exosomes based products. Stem Cell Drugs - A New Generation of Biopharmaceuticals and the other books in