The Chemistry and Biology of Nitroxyl HNO

The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule’s structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound’s foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research Provides a valuable coverage of HNO’s chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule Contains high quality content from recognized experts in both industry and academia

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  • Author : Fabio Doctorovich
  • Publisher : Elsevier
  • Pages : 424 pages
  • ISBN : 0128011645
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKThe Chemistry and Biology of Nitroxyl HNO

The Chemistry and Biology of Nitroxyl (HNO)

The Chemistry and Biology of Nitroxyl (HNO)
  • Author : Fabio Doctorovich,Patrick J. Farmer,Marcelo A. Marti
  • Publisher : Elsevier
  • Release : 01 September 2016
GET THIS BOOKThe Chemistry and Biology of Nitroxyl (HNO)

The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of

Free Nitroxyl Radicals

Free Nitroxyl Radicals
  • Author : E. Rozantsev
  • Publisher : Springer Science & Business Media
  • Release : 14 December 2013
GET THIS BOOKFree Nitroxyl Radicals

In the short time since the first nitroxyl radical was obtained in 1959, a new branch of chemical science has arisen and taken shape-the chemistry of stable nitroxyl radicals. The present book was written by E. G. Rozantsev, one of the pioneers in this field and a prominent specialist on stable radicals at the Division of Chemical and Biological Processes of the Institute of Chemical Physics, Academy of Sciences of the USSR. His numerous papers have contributed greatly to the present

Synthetic Explorations in the Pursuit of a Rapid, Photoactivatable, Nitroxyl Donor

Synthetic Explorations in the Pursuit of a Rapid, Photoactivatable, Nitroxyl Donor
  • Author : Mark Wesley Campbell
  • Publisher : Unknown Publisher
  • Release : 22 September 2021
GET THIS BOOKSynthetic Explorations in the Pursuit of a Rapid, Photoactivatable, Nitroxyl Donor

Nitroxyl (HNO) is a biologically relevant small molecule with considerable clinical promise for the treatment of heart failure. However, studies of the chemistry and biology of nitroxyl are hampered by its instability in aqueous solution. To aid in biological and chemical studies, nitroxyl donors (molecules that degrade to release HNO) have been synthesized which utilize a 3-hydroxy-2-naphthyl methyl (HNM) OH protecting group. Our group0́9s focus is on the synthesis of nitroxyl donors that rapidly release HNO under physiological

Nitrosation Reactions and the Chemistry of Nitric Oxide

Nitrosation Reactions and the Chemistry of Nitric Oxide
  • Author : D.L.H. Williams
  • Publisher : Elsevier
  • Release : 16 December 2004
GET THIS BOOKNitrosation Reactions and the Chemistry of Nitric Oxide

Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until

Chemistry and Chemists in Florence

Chemistry and Chemists in Florence
  • Author : Marco Fontani,Mary Virginia Orna,Mariagrazia Costa
  • Publisher : Springer
  • Release : 15 April 2016
GET THIS BOOKChemistry and Chemists in Florence

This brief offers a novel vision of the city of Florence, tracing the development of chemistry via the biographies of its most illustrious chemists. It documents not only important scientific research that came from the hands of Galileo Galilei and the physicists who followed in his footsteps, but also the growth of new disciplines such as chemistry, pharmaceutical chemistry, and biochemistry. It recounts how, in the Middle Ages, chemistry began as an applied science that served to bolster the Florentine

Chemical and Biochemical Physics, Kinetics and Thermodynamics

Chemical and Biochemical Physics, Kinetics and Thermodynamics
  • Author : Gennadiĭ Efremovich Zaikov
  • Publisher : Nova Publishers
  • Release : 22 September 2021
GET THIS BOOKChemical and Biochemical Physics, Kinetics and Thermodynamics

This book includes new and important research on antioxidants for chemistry and biology, kinetics and mechanisms of molecular, radical and ion reactions in chemistry and biochemistry, chemistry of ozone (reactions of ozone with organic and inorganic compounds, action of antiozonants), application of electron magnetic resonance and nuclear magnetic resonance in chemistry and biology, investigations of the structure and properties of nanocomposites (nanotubes, particularly), investigations on the structure and properties of nanocomposites (nanotubes, particularly), investigations of heterogeneous-heterophases mechanisms of reaction in

Porphyrins: Advances in Research and Application: 2011 Edition

Porphyrins: Advances in Research and Application: 2011 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release : 09 January 2012
GET THIS BOOKPorphyrins: Advances in Research and Application: 2011 Edition

Porphyrins: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Porphyrins. The editors have built Porphyrins: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Porphyrins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Porphyrins: Advances in Research and Application: 2011 Edition has been produced

NOx Related Chemistry

NOx Related Chemistry
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 08 January 2015
GET THIS BOOKNOx Related Chemistry

NOx Related Chemistry is a volume of a series that presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bio-inorganic to solid state studies. This acclaimed serial features reviews written by experts in the field and serves as an indispensable reference to advanced researchers. Each volume contains an index, and each chapter is fully referenced. Best-qualified scientists write on their own recent results dealing with basic fundamentals of NO-chemistry,

Biomedical Chemistry

Biomedical Chemistry
  • Author : Paul F. Torrence
  • Publisher : John Wiley & Sons
  • Release : 24 January 2000
GET THIS BOOKBiomedical Chemistry

How basic chemical ideas help advance the understanding and treatment of disease Biomedical Chemistry presents clear, concise coverage of the application of chemistry to drug discovery and determination of disease etiology, highlighting its role in the explosive growth of biotechnology and molecular biology. Through expert contributions from leading researchers in diverse fields, the book provides readers with an understanding of how fundamental chemical concepts are used in the development of novel approaches to the major problems in medicine today. The

Endothelial Dysfunction and Inflammation

Endothelial Dysfunction and Inflammation
  • Author : Shauna Dauphinee,Aly Karsan
  • Publisher : Springer Science & Business Media
  • Release : 24 September 2010
GET THIS BOOKEndothelial Dysfunction and Inflammation

Endothelial dysfunction is broadly defined as a disruption of the balance between vasoactive mediators and a propensity towards an inflammatory state. This volume provides an overview of the fields of endothelial dysfunction and inflammation through the discussion of topics ranging from the molecular biology of activated endothelial cells to the endothelium in inflammatory disease and therapeutic approaches targeting endothelial dysfunction. Topics include: Heterogeneity of the endothelium during inflammation, oxidative stress and endothelial dysfunction, biology and regulation of nitric oxide in

Nitrification

Nitrification
  • Author : Bess B. Ward,Daniel J. Arp,Martin G. Klotz
  • Publisher : American Society for Microbiology Press
  • Release : 25 March 2011
GET THIS BOOKNitrification

A full review of the latest research findings on microbes involved in conventional aerobic nitrification, anaerobic ammonia oxidation, and related processes. • Examines the four principal groups of nitrifying microbes including conventional aerobic bacterial ammonia oxidizers, recently discovered aerobic archaeal ammonia oxidizers, anaerobic ammonia-oxidizing planctomycetes, and nitrite-oxidizing bacteria. • Provides current information on the ecology, phylogeny, biochemistry, molecular biology, and genomics of each group of microbes. • Discusses the latest industrial applications of nitrification and anammox processes, and explores the ecology of nitrification

Free Radicals in Chemistry and Biology

Free Radicals in Chemistry and Biology
  • Author : Milan Lazar
  • Publisher : CRC Press
  • Release : 31 March 1989
GET THIS BOOKFree Radicals in Chemistry and Biology

Elementary radical reactions are described in terms of fundamental knowledge of organic chemistry and chemical physics in this valuable reference text. The complex radical processes of nonchain and chain mechanisms, such as dimerization, alkylation, polymerization, telomerization, halogenation pyrolysis, oxidation and combustion, are complemented by reactions in chemical lasers and in the cosmos, as well as by reactions in biological objects under normal or pathological metabolism. The text also provides the synthesis of facts from various fields of research and involves

Oxidation and Antioxidants in Organic Chemistry and Biology

Oxidation and Antioxidants in Organic Chemistry and Biology
  • Author : Evgeny T. Denisov,Igor B. Afanas'ev
  • Publisher : CRC Press
  • Release : 29 March 2005
GET THIS BOOKOxidation and Antioxidants in Organic Chemistry and Biology

Providing a comprehensive review of reactions of oxidation for different classes of organic compounds and polymers, and biological processes mediated by free radicals, Oxidation and Antioxidants in Organic Chemistry and Biology puts the data and bibliographical information you need into one easy-to-use resource. You will find up-to-date information about mechanisms of action of antioxidants, their reactivity, reactions of intermediates, synergism, and antioxidants with cyclic mechanism action. Supplying useful, quantitative data in tables that make the information easy to find, the

Enzymology and Molecular Biology of Carbonyl Metabolism 4

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  • Author : Henry Weiner,David W. Crabb,T. Geoffrey Flynn
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKEnzymology and Molecular Biology of Carbonyl Metabolism 4

The Sixth International Workshop on the Enzymology and Molecular Biology of Carbonyl Metabolism was held outside of Dublin, Ireland at the end of June, 1992. Prof. Keith Tipton, Chairman of the Biochemistry Department at Trinity College, kindly agreed to host the meeting. On behalf of all of us who attended I wish to extend our sincere thanks to the whole Tipton family for making us feel so welcome in Ireland. It has been a decade since the frrst workshop was held

Electron Spin Interactions in Chemistry and Biology

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  • Author : Gertz Likhtenshtein
  • Publisher : Springer
  • Release : 25 July 2016
GET THIS BOOKElectron Spin Interactions in Chemistry and Biology

This book presents the versatile and pivotal role of electron spin interactions in nature. It provides the background, methodologies and tools for basic areas related to spin interactions, such as spin chemistry and biology, electron transfer, light energy conversion, photochemistry, radical reactions, magneto-chemistry and magneto-biology. The book also includes an overview of designing advanced magnetic materials, optical and spintronic devices and photo catalysts. This monograph will be of interest to scientists and graduate students working in the areas related to