The Chemistry and Biology of Nitroxyl HNO

The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule’s structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound’s foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research Provides a valuable coverage of HNO’s chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule Contains high quality content from recognized experts in both industry and academia

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  • Author : Fabio Doctorovich
  • Publisher : Elsevier
  • Pages : 424 pages
  • ISBN : 0128011645
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKThe Chemistry and Biology of Nitroxyl HNO

The Chemistry and Biology of Nitroxyl (HNO)

The Chemistry and Biology of Nitroxyl (HNO)
  • Author : Fabio Doctorovich,Patrick J. Farmer,Marcelo A. Marti
  • Publisher : Elsevier
  • Release : 01 September 2016
GET THIS BOOKThe Chemistry and Biology of Nitroxyl (HNO)

The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of

The Chemical Biology of Nitrogen

The Chemical Biology of Nitrogen
  • Author : Christopher T Walsh
  • Publisher : Royal Society of Chemistry
  • Release : 21 May 2021
GET THIS BOOKThe Chemical Biology of Nitrogen

From DNA and RNA to proteins and vitamins the role of nitrogen is central in organismal metabolism. The Chemical Biology of Nitrogen comprehensively examines how the chemistry available to both inorganic and organic nitrogen compounds both enable and conditions the vast array of nitrogen biologies. This book provides a chemocentric approach to both the inorganic and organic chemical biology of nitrogen. Following an introduction to nitrogen trivalency the book progresses through the logic of inorganic nitrogen metabolism and organic nitrogen

Chemistry and Chemists in Florence

Chemistry and Chemists in Florence
  • Author : Marco Fontani,Mary Virginia Orna,Mariagrazia Costa
  • Publisher : Springer
  • Release : 15 April 2016
GET THIS BOOKChemistry and Chemists in Florence

This brief offers a novel vision of the city of Florence, tracing the development of chemistry via the biographies of its most illustrious chemists. It documents not only important scientific research that came from the hands of Galileo Galilei and the physicists who followed in his footsteps, but also the growth of new disciplines such as chemistry, pharmaceutical chemistry, and biochemistry. It recounts how, in the Middle Ages, chemistry began as an applied science that served to bolster the Florentine

Nitrosation Reactions and the Chemistry of Nitric Oxide

Nitrosation Reactions and the Chemistry of Nitric Oxide
  • Author : D.L.H. Williams
  • Publisher : Elsevier
  • Release : 16 December 2004
GET THIS BOOKNitrosation Reactions and the Chemistry of Nitric Oxide

Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until

Porphyrins: Advances in Research and Application: 2011 Edition

Porphyrins: Advances in Research and Application: 2011 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release : 09 January 2012
GET THIS BOOKPorphyrins: Advances in Research and Application: 2011 Edition

Porphyrins: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Porphyrins. The editors have built Porphyrins: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Porphyrins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Porphyrins: Advances in Research and Application: 2011 Edition has been produced

Free Nitroxyl Radicals

Free Nitroxyl Radicals
  • Author : E. Rozantsev
  • Publisher : Springer Science & Business Media
  • Release : 14 December 2013
GET THIS BOOKFree Nitroxyl Radicals

In the short time since the first nitroxyl radical was obtained in 1959, a new branch of chemical science has arisen and taken shape-the chemistry of stable nitroxyl radicals. The present book was written by E. G. Rozantsev, one of the pioneers in this field and a prominent specialist on stable radicals at the Division of Chemical and Biological Processes of the Institute of Chemical Physics, Academy of Sciences of the USSR. His numerous papers have contributed greatly to the present

Synthetic Explorations in the Pursuit of a Rapid, Photoactivatable, Nitroxyl Donor

Synthetic Explorations in the Pursuit of a Rapid, Photoactivatable, Nitroxyl Donor
  • Author : Mark Wesley Campbell
  • Publisher : Unknown Publisher
  • Release : 24 January 2022
GET THIS BOOKSynthetic Explorations in the Pursuit of a Rapid, Photoactivatable, Nitroxyl Donor

Nitroxyl (HNO) is a biologically relevant small molecule with considerable clinical promise for the treatment of heart failure. However, studies of the chemistry and biology of nitroxyl are hampered by its instability in aqueous solution. To aid in biological and chemical studies, nitroxyl donors (molecules that degrade to release HNO) have been synthesized which utilize a 3-hydroxy-2-naphthyl methyl (HNM) OH protecting group. Our group0́9s focus is on the synthesis of nitroxyl donors that rapidly release HNO under physiological

Nitric Oxide

Nitric Oxide
  • Author : Lester Packer,Enrique Cadenas
  • Publisher : Gulf Professional Publishing
  • Release : 01 September 2005
GET THIS BOOKNitric Oxide

Since the inception of the series, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all field of life sciences. This final volume in the five-part Nitric Oxide series supplements MIE volumes 268, 269, 301 and 359. Nitric Oxide impinges on a wide range of fields in biological research, particularly in the areas of biomedicine and cell and organic biology, as well

Free Radicals in Chemistry and Biology

Free Radicals in Chemistry and Biology
  • Author : Milan Lazar
  • Publisher : CRC Press
  • Release : 31 March 1989
GET THIS BOOKFree Radicals in Chemistry and Biology

Elementary radical reactions are described in terms of fundamental knowledge of organic chemistry and chemical physics in this valuable reference text. The complex radical processes of nonchain and chain mechanisms, such as dimerization, alkylation, polymerization, telomerization, halogenation pyrolysis, oxidation and combustion, are complemented by reactions in chemical lasers and in the cosmos, as well as by reactions in biological objects under normal or pathological metabolism. The text also provides the synthesis of facts from various fields of research and involves

Nitrification

Nitrification
  • Author : Bess B. Ward,Daniel J. Arp,Martin G. Klotz
  • Publisher : American Society for Microbiology Press
  • Release : 25 March 2011
GET THIS BOOKNitrification

A full review of the latest research findings on microbes involved in conventional aerobic nitrification, anaerobic ammonia oxidation, and related processes. • Examines the four principal groups of nitrifying microbes including conventional aerobic bacterial ammonia oxidizers, recently discovered aerobic archaeal ammonia oxidizers, anaerobic ammonia-oxidizing planctomycetes, and nitrite-oxidizing bacteria. • Provides current information on the ecology, phylogeny, biochemistry, molecular biology, and genomics of each group of microbes. • Discusses the latest industrial applications of nitrification and anammox processes, and explores the ecology of nitrification

Endothelial Dysfunction and Inflammation

Endothelial Dysfunction and Inflammation
  • Author : Shauna Dauphinee,Aly Karsan
  • Publisher : Springer Science & Business Media
  • Release : 24 September 2010
GET THIS BOOKEndothelial Dysfunction and Inflammation

Endothelial dysfunction is broadly defined as a disruption of the balance between vasoactive mediators and a propensity towards an inflammatory state. This volume provides an overview of the fields of endothelial dysfunction and inflammation through the discussion of topics ranging from the molecular biology of activated endothelial cells to the endothelium in inflammatory disease and therapeutic approaches targeting endothelial dysfunction. Topics include: Heterogeneity of the endothelium during inflammation, oxidative stress and endothelial dysfunction, biology and regulation of nitric oxide in

Gasotransmitters in Plants

Gasotransmitters in Plants
  • Author : Lorenzo Lamattina,Carlos García-Mata
  • Publisher : Springer
  • Release : 01 September 2016
GET THIS BOOKGasotransmitters in Plants

This book describes the three gasotransmitters nitric oxide (NO), hydrogen sulphide (H2S) and carbon monoxide (CO) and their function as intracellular signalling molecules in plants. Common properties are shared by NO, H2S and CO: they are beneficial at low concentrations but hazardous in higher amounts; they are small molecules of gas; they can freely cross cell membranes; their effects do not rely on receptors; they are generated enzymatically and their production is regulated; their functions can be mimicked

Molecular Toxicology

Molecular Toxicology
  • Author : P. David Josephy,Bengt Mannervik
  • Publisher : Oxford University Press on Demand
  • Release : 24 January 2022
GET THIS BOOKMolecular Toxicology

The science of toxicology has progressed considerably since Molecular Toxicology was first published in 1997. New advances in biochemical and molecular biological experimental techniques have helped researchers understand the precise effects of toxins and foreign compounds on living things at the molecular, cellular, and organismal levels. Breakthrough research has recently been completed illuminating the human genome and the role of enzymes in toxic biochemical reaction mechanisms. Toxicology now covers drug metabolism and design, carcinogenesis, programmed cell death, and DNA repair, among

Oxidation and Antioxidants in Organic Chemistry and Biology

Oxidation and Antioxidants in Organic Chemistry and Biology
  • Author : Evgeny T. Denisov,Igor B. Afanas'ev
  • Publisher : CRC Press
  • Release : 29 March 2005
GET THIS BOOKOxidation and Antioxidants in Organic Chemistry and Biology

Providing a comprehensive review of reactions of oxidation for different classes of organic compounds and polymers, and biological processes mediated by free radicals, Oxidation and Antioxidants in Organic Chemistry and Biology puts the data and bibliographical information you need into one easy-to-use resource. You will find up-to-date information about mechanisms of action of antioxidants, their reactivity, reactions of intermediates, synergism, and antioxidants with cyclic mechanism action. Supplying useful, quantitative data in tables that make the information easy to find, the

Postharvest Biology and Nanotechnology

Postharvest Biology and Nanotechnology
  • Author : Gopinadhan Paliyath,Jayasankar Subramanian,Loong-Tak Lim,K. S. Subramanian,Avtar K. Handa,Autar K. Mattoo
  • Publisher : Wiley-Blackwell
  • Release : 30 January 2019
GET THIS BOOKPostharvest Biology and Nanotechnology

A comprehensive introduction to the physiology, biochemistry, and molecular biology of produce growth, paired with cutting-edge technological advances in produce preservation Revised and updated, the second edition of Postharvest Biology and Nanotechnology explores the most recent developments in postharvest biology and nanotechnology. Since the publication of the first edition, there has been an increased understanding of the developmental physiology, biochemistry, and molecular biology during early growth, maturation, ripening, and postharvest conditions. The contributors—noted experts in the field—review the