The Comprehensive Sourcebook of Bacterial Protein Toxins

The Comprehensive Sourcebook of Bacterial Protein Toxins
  • Author : Joseph E. Alouf,Daniel Ladant,Michel R. Popoff
  • Publisher : Elsevier
  • Release : 20 December 2005
GET THIS BOOKThe Comprehensive Sourcebook of Bacterial Protein Toxins

This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates. Edited by two

ADP-Ribosylating Toxins

ADP-Ribosylating Toxins
  • Author : Klaus Aktories
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKADP-Ribosylating Toxins

ADP-ribosylating toxins have been the focus of intensive research for more than 30 years. Researchers from diverse fields of science have taken an interest in these bacterial toxins; they are studied, for example, by microbiologists, biochemists, cell biologists, and pharmacologists. There are two principal reasons for the broad and still growing interest in ADP ribosylating toxins. First, insights into the structure and functions of the toxins might be the key to prevention and treatment of diseases caused by the toxin-producing infectious

Clostridial Neurotoxins

Clostridial Neurotoxins
  • Author : Cesare Montecucco
  • Publisher : Springer Science & Business Media
  • Release : 11 November 2013
GET THIS BOOKClostridial Neurotoxins

Tetanus has been known from the very beginning of medical literature since it was first described by Hyppocrates of Cos in the fifth century B.C. For 24 centuries it was considered a neuro logical disease until the breakthrough of CARLE and RATIONE (1884) who demonstrated its infectious etiology. Following the establishment of purified cultures of Clostridium tetani(KITASATO 1889), FABER (1890), and TIZZONI and CATIANI (1890) demon strated that the disease is actually an intoxication caused by a proteic neurotoxin. This toxin was shown

Botulinum Neurotoxins

Botulinum Neurotoxins
  • Author : Andreas Rummel,Thomas Binz
  • Publisher : Springer Science & Business Media
  • Release : 14 December 2012
GET THIS BOOKBotulinum Neurotoxins

The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule

Pore-Forming Toxins

Pore-Forming Toxins
  • Author : Gisou van der Goot
  • Publisher : Springer Science & Business Media
  • Release : 12 March 2001
GET THIS BOOKPore-Forming Toxins

Pore-forming toxins are virulence factors produced by a great variety of pathogenic bacteria ranging from the Gram-positive Staphylococcus aureus to the Gram-negative Helicobacter pylory. The recent studies reviewed in this volume describe the progress that has been made in dissecting the different steps of the mode of action of these proteins which generally include binding to specific cell surface receptors, oligomerization into ring like structures and membrane perforation.

Sourcebook of Bacterial Protein Toxins

Sourcebook of Bacterial Protein Toxins
  • Author : Joseph E. Alouf,John H. Freer
  • Publisher : Unknown Publisher
  • Release : 24 January 1991
GET THIS BOOKSourcebook of Bacterial Protein Toxins

Written by an international team of leading scientists, this volume draws together a wealth of information on the structure, regulation, and activity of bacterial protein toxins. A comprehensive sourcebook on bacterial toxins, Sourcebook of Bacterial Protein Toxins is the first book designed to draw together current knowledge on these toxins. The 22 chapters of this book have been written by 44 internationally known specialists who have significantly contributed to the progress in the domains covered. This book will appeal to a wide

Botulinum and Tetanus Neurotoxins

Botulinum and Tetanus Neurotoxins
  • Author : B.R. DasGupta
  • Publisher : Springer Science & Business Media
  • Release : 11 November 2013
GET THIS BOOKBotulinum and Tetanus Neurotoxins

Three days in Madison have thoroughly modified my view on clostridial neurotoxins. While still realizing the numerous activating, modifying and protective inputs, I cannot judge the meaningfulness of the meeting impartially. Neither may the reader expect a complete summary of all presentations. Collected in this volume, they speak for themselves without requiring an arbiter. Instead I shall write down my very personal opinions as a researcher who has studied clostridial neurotoxins for nearly 25 years. Comparable conferences have been rare during

Pore-forming Peptides and Protein Toxins

Pore-forming Peptides and Protein Toxins
  • Author : Gianfranco Menestrina,M. Dalla Sera
  • Publisher : CRC Press
  • Release : 30 January 2003
GET THIS BOOKPore-forming Peptides and Protein Toxins

Pore-forming proteins and peptides play a central role in bacterial pathogenesis, the immune response, defense from venomous attack, and innate immunity. These proteins attack and eliminate other organisms by punching an aqueous channel through their membranes, which disrupts appropriate cell function. The discovery of this cellular interaction has

The State of Food Security and Nutrition in the World 2018

The State of Food Security and Nutrition in the World 2018
  • Author : Food and Agriculture Organization of the United Nations
  • Publisher : Food & Agriculture Org.
  • Release : 14 September 2018
GET THIS BOOKThe State of Food Security and Nutrition in the World 2018

New evidence this year corroborates the rise in world hunger observed in this report last year, sending a warning that more action is needed if we aspire to end world hunger and malnutrition in all its forms by 2030. Updated estimates show the number of people who suffer from hunger has been growing over the past three years, returning to prevailing levels from almost a decade ago. Although progress continues to be made in reducing child stunting, over 22 percent of children

Novel Strategies in the Design and Production of Vaccines

Novel Strategies in the Design and Production of Vaccines
  • Author : Sara Cohen,Avigdor Shafferman
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOKNovel Strategies in the Design and Production of Vaccines

Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanity. Common pathogens, once believed to be under control, acquire increased virulence and resistance to drugs, while exotic microorganisms emerged from hidden reservoirs to cause yet incurable diseases in humans. These changes, together with epidemic outbreaks related to political and socio-economic

Natural Toxins 2

Natural Toxins 2
  • Author : Bal Ram Singh,Anthony T. Tu
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKNatural Toxins 2

From beach encounters, aquaculture perils, and processed-food poisoning to snake bites and biological warfare, natural toxins seem never to be far from the public's sight. A better understanding of toxins in terms of their origin, structure, structure-function relation ships, mechanism of action, and detection and diagnosis is of utmost importance to human and animal food safety, nutrition, and health. In addition, it is now clear that many of the toxins can be used as scientific tools to explore the molecular

The Comprehensive Sourcebook of Bacterial Protein Toxins

The Comprehensive Sourcebook of Bacterial Protein Toxins
  • Author : John H. Freer,Joseph E. Alouf
  • Publisher : Unknown Publisher
  • Release : 24 January 1999
GET THIS BOOKThe Comprehensive Sourcebook of Bacterial Protein Toxins

The Comprehensive Sourcebook of Bacterial Protein Toxins, Second Edition, provides an up-to-date description of the great advances made in our understanding of the structure, genetics, cellular, and molecular mechanisms of action of bacterial protein toxins over the past decade. This work follows and expands on the first edition (published in 1991), with 70% totally new content and full-color illustrations. Molecular biology, microbiology, immunology, cell biology, protein engineering, structural biochemistry, and clinical research in infectious diseases are brought together to provide a complete

Cell Physiology Source Book

Cell Physiology Source Book
  • Author : Nicholas Sperelakis
  • Publisher : Elsevier
  • Release : 02 December 2012
GET THIS BOOKCell Physiology Source Book

This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The Third Edition contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, the regulation of cell division, and programmed cell death. Completely revised and updated -