The Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target, and present various physiological parameters for in vivo studies. The book includes preclinical trials and research, along with information on FDA approval. Covers both in silico methods and experimental protocols for vaccine and drug development in a single, accessible volume Offers a holistic accounting of how developments in bioinformatics and large experimental datasets can be used in the development of vaccines and drugs Shows researchers the entire gamut of current therapies, ranging from computational inputs to animal studies Reviews the most current, cutting-edge research available on vaccine and drug design and development

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  • Author : Tarun Kumar Bhatt
  • Publisher : Academic Press
  • Pages : 308 pages
  • ISBN : 0128214759
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKThe Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines
  • Author : Tarun Kumar Bhatt,Surendra Nimesh
  • Publisher : Academic Press
  • Release : 21 January 2021
GET THIS BOOKThe Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target,

Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic?

Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic?
  • Author : Rubén Bueno-Marí, Juan-Carlos Saiz,Óscar D. Salomón, Luis C. Villamil-Jiménez,Jorg Heukelbach,Carlos H. Alencar,Paul Armstrong,Paulo Henrique Rosado-de-Castro,Pedro M. Pimentel-Coelho
  • Publisher : Frontiers Media SA
  • Release : 12 April 2018
GET THIS BOOKZika Virus: What Have We Learnt Since the Start of the Recent Epidemic?

The considerable number of viral infectious disease threats that have emerged since the beginning of the 21st century have shown the need to dispose global and coordinated responses to fight properly and efficiently against them. Severe acute respiratory syndrome (2003), avian influenza in humans (2005), A(H1N1) pandemic influenza (2009), Middle East respiratory syndrome coronavirus (MERS-CoV) (2012 onward) and Ebola virus disease (2014-2015) are some of the most important examples. The latest emerging and devastating threat was Zika virus, an arbovirus that provoked

Development of Vaccines

Development of Vaccines
  • Author : Manmohan Singh,Indresh K. Srivastava
  • Publisher : John Wiley & Sons
  • Release : 11 October 2011
GET THIS BOOKDevelopment of Vaccines

Development of Vaccines: From Discovery to Clinical Testing outlines the critical steps, and analytical tools and techniques, needed to take a vaccine from discovery through a successful clinical trial. Contributions from leading experts in the critical areas of vaccine expression, purification, formulation, pre-clinical testing and regulatory submissions make this book an authoritative collection of issues, challenges and solutions for progressing a biologic drug formulation from its early stage of discovery into its final clinical testing. A section with details and

Novel Strategies in the Design and Production of Vaccines

Novel Strategies in the Design and Production of Vaccines
  • Author : Sara Cohen,Avigdor Shafferman
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOKNovel Strategies in the Design and Production of Vaccines

Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanity. Common pathogens, once believed to be under control, acquire increased virulence and resistance to drugs, while exotic microorganisms emerged from hidden reservoirs to cause yet incurable diseases in humans. These changes, together with epidemic outbreaks related to political and socio-economic

Statistical Methods for Evaluating Safety in Medical Product Development

Statistical Methods for Evaluating Safety in Medical Product Development
  • Author : A. Lawrence Gould
  • Publisher : John Wiley & Sons
  • Release : 08 December 2014
GET THIS BOOKStatistical Methods for Evaluating Safety in Medical Product Development

This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during medical product development. Each chapter provides sufficient detail to the reader to undertake the design and analysis of experiments at various stages of product development, including comprehensive references to the

Preventing Chemical Weapons

Preventing Chemical Weapons
  • Author : Michael Crowley,Malcolm Dando,Lijun Shang
  • Publisher : Royal Society of Chemistry
  • Release : 20 August 2018
GET THIS BOOKPreventing Chemical Weapons

The life and chemical sciences are in the midst of a period of rapid and revolutionary transformation that will undoubtedly bring societal benefits but also have potentially malign applications, notably in the development of chemical weapons. Such concerns are exacerbated by the unstable international security environment and the changing nature of armed conflict, which could fuel a desire by certain States to retain and use existing chemical weapons, as well as increase State interest in creating new weapons; whilst a

Design of Experiments and Advanced Statistical Techniques in Clinical Research

Design of Experiments and Advanced Statistical Techniques in Clinical Research
  • Author : Basavarajaiah D. M.,Bhamidipati Narasimha Murthy
  • Publisher : Springer Nature
  • Release : 05 November 2020
GET THIS BOOKDesign of Experiments and Advanced Statistical Techniques in Clinical Research

Recent Statistical techniques are one of the basal evidence for clinical research, a pivotal in handling new clinical research and in evaluating and applying prior research. This book explores various choices of statistical tools and mechanisms, analyses of the associations among different clinical attributes. It uses advanced statistical methods to describe real clinical data sets, when the clinical processes being examined are still in the process. This book also discusses distinct methods for building predictive and probability distribution models in

Computer Simulations of Protein Structures and Interactions

Computer Simulations of Protein Structures and Interactions
  • Author : Serafin Fraga,J.M.Robert Parker,Jennifer M. Pocock
  • Publisher : Springer Science & Business Media
  • Release : 17 April 2013
GET THIS BOOKComputer Simulations of Protein Structures and Interactions

Protein engineering endeavors to design new peptides and proteins or to change the structural and/or functional characteristics of existing ones for specific purposes, opening the way for the development of new drugs. This work develops in a comprehensive way the theoretical formulation for the methods used in computer-assisted modeling and predictions, starting from the basic concepts and proceeding to the more sophisticated methods, such as Monte Carlo and molecular dynamics. An evaluation of the approximations inherent to the simulations