The Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target, and present various physiological parameters for in vivo studies. The book includes preclinical trials and research, along with information on FDA approval. Covers both in silico methods and experimental protocols for vaccine and drug development in a single, accessible volume Offers a holistic accounting of how developments in bioinformatics and large experimental datasets can be used in the development of vaccines and drugs Shows researchers the entire gamut of current therapies, ranging from computational inputs to animal studies Reviews the most current, cutting-edge research available on vaccine and drug design and development

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  • Author : Tarun Kumar Bhatt
  • Publisher : Academic Press
  • Pages : 308 pages
  • ISBN : 0128214716
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKThe Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines
  • Author : Tarun Kumar Bhatt,Surendra Nimesh
  • Publisher : Academic Press
  • Release : 05 February 2021
GET THIS BOOKThe Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target,

The Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines
  • Author : Tarun Kumar Bhatt,Surendra Nimesh
  • Publisher : Academic Press
  • Release : 21 January 2021
GET THIS BOOKThe Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target,

Human Vaccines

Human Vaccines
  • Author : Kayvon Modjarrad,Wayne C. Koff
  • Publisher : Academic Press
  • Release : 15 October 2016
GET THIS BOOKHuman Vaccines

Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics—among other disciplines—that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens. For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed Given the rapidity with

Novel Strategies in the Design and Production of Vaccines

Novel Strategies in the Design and Production of Vaccines
  • Author : Sara Cohen,Avigdor Shafferman
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOKNovel Strategies in the Design and Production of Vaccines

Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanity. Common pathogens, once believed to be under control, acquire increased virulence and resistance to drugs, while exotic microorganisms emerged from hidden reservoirs to cause yet incurable diseases in humans. These changes, together with epidemic outbreaks related to political and socio-economic

Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics

Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics
  • Author : Lisa Plitnick,Danuta Herzyk
  • Publisher : Academic Press
  • Release : 27 June 2013
GET THIS BOOKNonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics

Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics is a complete reference devoted to the nonclinical safety assessment of novel biopharmaceuticals, biosimilars, vaccines, cell and gene therapies and blood products. This book compares and contrasts these types of biologics with one another and with small molecule drugs, while incorporating the most current and essential international regulatory documents. Each section discusses a different type of biologic, as well as early characterization strategies, principles of study design, preclinical pharmacokinetics and

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents
  • Author : Manju Rawat Singh,Deependra Singh,Jagat Kanwar,Nagendra Singh Chauhan
  • Publisher : Academic Press
  • Release : 07 April 2020
GET THIS BOOKAdvances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents provides sound data on the utility of biological and plant-based drugs and describes challenges faced in all aspects offering indispensable strategies to use in the development of bioactive medicines. Bioactive based medications are commonly used throughout the world and have been recognized by physicians and patients for their therapeutic efficacy. Bioactive formulations, including their subordinates and analogs, address 50% of all medicines in clinical practice. Novel bioactive

Rare Diseases and Orphan Products

Rare Diseases and Orphan Products
  • Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Accelerating Rare Diseases Research and Orphan Product Development
  • Publisher : National Academies Press
  • Release : 03 April 2011
GET THIS BOOKRare Diseases and Orphan Products

Rare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions is challenging. The Institute of Medicine (IOM) recommends implementing an integrated national strategy to promote rare diseases research and product development.

Novel Coronavirus 2019

Novel Coronavirus 2019
  • Author : Amit Kumar,Ajit Kumar Saxena,Gwo Giun (Chris) Lee,Amita Kashyap,G. Jyothsna
  • Publisher : Springer Nature
  • Release : 26 September 2020
GET THIS BOOKNovel Coronavirus 2019

This book highlights the genomic findings, observations, and analysis of DNA/RNA sequences and protein structure of the dreadful virus of this decade- COVID-19. The Corona group of viruses though known species, the strain that caused the Pandemic of 2019 is a completely new strain, belonging to the same corona family with a novel genetic make-up. This makes it a new pathogen which is causing the current outbreak leaving the global scientific community clueless of any therapeutic breakthrough. NCOV enjoys life

Nutrition and Disease

Nutrition and Disease
  • Author : Kenneth Lundstrom
  • Publisher : Cambridge Scholars Publishing
  • Release : 24 February 2020
GET THIS BOOKNutrition and Disease

Nutrition is an essential part of life. It affects our health and can be applied in the prevention and treatment of disease. Substantial interventions in dietary intake and lifestyle changes have been demonstrated to cause significant decrease in disease risk in in the general population and also in patients suffering from various diseases. Traditional plant-based diets and medicines have received much attention as an alternative to modern science-based drugs, while recent technology development in bioinformatics, genomics, and proteomics has provided

Mucosal Delivery of Drugs and Biologics in Nanoparticles

Mucosal Delivery of Drugs and Biologics in Nanoparticles
  • Author : Pavan Muttil,Nitesh K. Kunda
  • Publisher : Springer Nature
  • Release : 18 March 2020
GET THIS BOOKMucosal Delivery of Drugs and Biologics in Nanoparticles

Nanotechnology has revolutionized the approach to designing and developing novel drug delivery systems. The last two decades have seen a great interest in the use of nanotechnology to offer efficient ways of delivering new and existing drugs and macromolecules. The focus of this book is the application of nanotechnology to deliver drugs and biological agents by the mucosal routes of administration i.e. nasal, pulmonary, buccal, and oral routes. It provides an overview of nanotechnology in drug delivery with a

Microbial Diversity in Ecosystem Sustainability and Biotechnological Applications

Microbial Diversity in Ecosystem Sustainability and Biotechnological Applications
  • Author : Tulasi Satyanarayana,Bhavdish Narain Johri,Subrata Kumar Das
  • Publisher : Springer
  • Release : 17 July 2019
GET THIS BOOKMicrobial Diversity in Ecosystem Sustainability and Biotechnological Applications

This book discusses microbial diversity in various habitats and environments, its role in ecosystem maintenance, and its potential applications (e.g. biofertilizers, biocatalysts, antibiotics, other bioactive compounds, exopolysaccharides etc.). The respective chapters, all contributed by renowned experts, offer cutting-edge information in the fields of microbial ecology and biogeography. The book explains the reasons behind the occurrence of various biogeographies and highlights recent tools (e.g. metagenomics) that can aid in biogeography studies by providing information on nucleic acid sequence data,

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes
  • Author : Vijay Mishra,Prashant Kesharwani,Mohd Cairul Iqbal Mohd Amin,Arun Iyer
  • Publisher : Academic Press
  • Release : 23 May 2017
GET THIS BOOKNanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and

Biomedical Innovations to Combat COVID-19

Biomedical Innovations to Combat COVID-19
  • Author : Sergio Rosales-Mendoza,Mauricio Comas-García,Omar González-Ortega
  • Publisher : Academic Press
  • Release : 15 October 2021
GET THIS BOOKBiomedical Innovations to Combat COVID-19

Biomedical Innovations to Combat COVID-19 provides an updated overview on the development of vaccines, antiviral drugs and nanomaterials, and diagnostic methods for the fight against COVID-19. Perspectives on such technologies are identified, discussed, and enriched with figures for easy understanding and applicability. Furthermore, it contains basic aspects of virology, immunology, and antiviral drugs that are needed to fully appreciate these innovations. This book is split into four sections: introduction, presenting basic virologic and epidemiological aspects of COVID-19; vaccines against COVID-19,

Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic?

Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic?
  • Author : Rubén Bueno-Marí, Juan-Carlos Saiz,Óscar D. Salomón, Luis C. Villamil-Jiménez,Jorg Heukelbach,Carlos H. Alencar,Paul Armstrong,Paulo Henrique Rosado-de-Castro,Pedro M. Pimentel-Coelho
  • Publisher : Frontiers Media SA
  • Release : 12 April 2018
GET THIS BOOKZika Virus: What Have We Learnt Since the Start of the Recent Epidemic?

The considerable number of viral infectious disease threats that have emerged since the beginning of the 21st century have shown the need to dispose global and coordinated responses to fight properly and efficiently against them. Severe acute respiratory syndrome (2003), avian influenza in humans (2005), A(H1N1) pandemic influenza (2009), Middle East respiratory syndrome coronavirus (MERS-CoV) (2012 onward) and Ebola virus disease (2014-2015) are some of the most important examples. The latest emerging and devastating threat was Zika virus, an arbovirus that provoked