The Detection of Biomarkers

Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers. The Detection of Biomarkers presents developments in biomarker detection, including methods tools and strategies, biosensor design, materials, and applications. The book presents methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical, and therefore highly practical for use in clinical research scenarios. This volume situates biomarker detection in its research context and sets out future prospects for the area. Its 20 chapters offer a comprehensive coverage of biomarkers, including progress on nanotechnology, biosensor types, synthesis, immobilization, and applications in various fields. The book also demonstrates, for students, how to synthesize and immobilize biosensors for biomarker assay. It offers researchers real alternative and innovative ways to think about the field of biomarker detection, increasing the reliability, precision and accuracy of biomarker detection. Locates biomarker detection in its research context, setting out present and future prospects Allows clinical researchers to compare various biomarker assays systematically Presents new methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical Gives innovative biomarker assays that are viable alternatives to current complex methods Helps clinical researchers who need reliable, precise and accurate biomarker detection methods

Produk Detail:

  • Author : Sibel A. Ozkan
  • Publisher : Academic Press
  • Pages : 614 pages
  • ISBN : 0128230754
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKThe Detection of Biomarkers

The Detection of Biomarkers

The Detection of Biomarkers
  • Author : Sibel A. Ozkan,Nurgul K. Bakirhan,Fariba Mollaraosouli
  • Publisher : Academic Press
  • Release : 05 December 2021
GET THIS BOOKThe Detection of Biomarkers

Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers. The Detection of Biomarkers presents developments in biomarker detection, including methods tools and strategies, biosensor design, materials, and applications. The book presents methods, materials and procedures that are simple,

Immunosensing for Detection of Protein Biomarkers

Immunosensing for Detection of Protein Biomarkers
  • Author : Huangxian Ju,Guosong Lai,Feng Yan
  • Publisher : Elsevier
  • Release : 18 May 2017
GET THIS BOOKImmunosensing for Detection of Protein Biomarkers

Immunosensing for Detection of Protein Biomarkers not only introduces the principles, methods, and classification of immunoassay, but also presents the latest achievements in areas such as electrochemical immunosensors, nanoprobe-based immunoassay, chemiluminescence immunoassay, electrochemiluminescent immunoassay, multianalyte immunoassay, optical imaging for immunoassay, signal amplification for immunoassay, and so on. In recent years, immunosensing and immunoassay methods have attracted considerable interest due to their applications in different fields, particularly clinical diagnosis. Although a large number of academic papers in immunosensing and immunoassay have

Biomarkers in Cancer Screening and Early Detection

Biomarkers in Cancer Screening and Early Detection
  • Author : Sudhir Srivastava
  • Publisher : John Wiley & Sons
  • Release : 07 June 2017
GET THIS BOOKBiomarkers in Cancer Screening and Early Detection

Prepared by world leaders on this topic, Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and use in developing personalized cancer treatment. Offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers Provides immediately actionable information – and hopefully also inspiration – to move discovery and clinical application forward Offers vital knowledge to

Biomarkers and Biosensors

Biomarkers and Biosensors
  • Author : Ajit Sadana,Neeti Sadana
  • Publisher : Newnes
  • Release : 08 December 2014
GET THIS BOOKBiomarkers and Biosensors

Biomarkers and Biosensors offers thorough coverage of biomarker/biosensor interaction, current research trends, and future developments in applications of drug discovery. This book is useful to researchers in this field as well as clinicians interested in new developments in early detection and diagnosis of disease or the mode of operation of biomarkers. Biomarkers and Biosensors also emphasizes kinetics, and clearly delineates how this influences the biomarker market. Offers thorough coverage of the kinetics of biomarker interaction with the biosensor surface

Quantitative Multiplex Detection of Biomarkers on a Waveguide-based Biosensor Using Quantum Dots

Quantitative Multiplex Detection of Biomarkers on a Waveguide-based Biosensor Using Quantum Dots
  • Author : Anonim
  • Publisher : Unknown Publisher
  • Release : 21 January 2022
GET THIS BOOKQuantitative Multiplex Detection of Biomarkers on a Waveguide-based Biosensor Using Quantum Dots

The quantitative, simultaneous detection of multiple biomarkers with high sensitivity and specificity is critical for biomedical diagnostics, drug discovery and biomarker characterization [Wilson 2006, Tok 2006, Straub 2005, Joos 2002, Jani 2000]. Detection systems relying on optical signal transduction are, in general, advantageous because they are fast, portable, inexpensive, sensitive, and have the potential for multiplex detection of analytes of interest. However, conventional immunoassays for the detection of biomarkers, such as the Enzyme Linked Immunosorbant Assays (ELISAs) are semi-quantitative, time consuming and insensitive. ELISA assays

Nanobiosensors

Nanobiosensors
  • Author : Aiguo Wu,Waheed S. Khan
  • Publisher : John Wiley & Sons
  • Release : 02 June 2020
GET THIS BOOKNanobiosensors

Containing cutting edge research on the hot topic of nanobiosensor, this book will become highly read Biosensor research has recently re-emerged as most vibrant area in recent years particularly after the advent of novel nanomaterials of multidimensional features and compositions. Nanomaterials of different types and striking properties have played a positive role in giving the boost and accelerated pace to biosensors development technology. Nanobiosensors - From Design to Applications covers several aspects of biosensors beginning from the basic concepts to

Electrochemical Detection of Cancer Biomarkers

Electrochemical Detection of Cancer Biomarkers
  • Author : Gary Conrad Jensen
  • Publisher : Unknown Publisher
  • Release : 21 January 2022
GET THIS BOOKElectrochemical Detection of Cancer Biomarkers

The detection of proteins with clinical and diagnostic value has become an important method for detecting and following the progression of cancers. Electrochemical detection of these biomarkers offers an inexpensive and highly sensitive detection scheme for cancer biomarkers with the potential for point-of-care diagnostics. Multi-enzyme carriers linked with an antibody can accomplish amplification of electrochemical protein detection, as a secondary antibody in sandwich immunoassay. A multi-enzyme-antibody-carbon nanotube prepared using functionalized multiwalled carbon nanotubes, anti-prostate specific antigen antibodies (anti-PSA), and horseradish

Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers

Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers
  • Author : Pallaval Veera Bramhachari,Nageswara Rao Reddy Neelapu
  • Publisher : Springer Nature
  • Release : 21 July 2020
GET THIS BOOKRecent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers

This book describes various novel biomarkers for the early diagnosis of gastrointestinal (GI) cancers. It also highlights recent advances in understanding the role of molecular markers and biomarkers, such as volatile biomarkers, serum biomarkers, predictive and prognostic molecular markers for the early detection of GI cancers. Further, it discusses novel biomarkers, including circulating microRNAs, serum microRNA and plasma microRNA in GI cancer. The book presents breakthrough technologies like ultra-sensitive nano-chips, nanosensors, nanodevices, biosensors, electrochemical biosensors, optical biosensors, DNA biosensors, synthetic

Biosensor Based Advanced Cancer Diagnostics

Biosensor Based Advanced Cancer Diagnostics
  • Author : Raju Khan,Arpana Parihar,S.K. Sanghi
  • Publisher : Academic Press
  • Release : 25 August 2021
GET THIS BOOKBiosensor Based Advanced Cancer Diagnostics

Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient’s life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have

Cancer Biomarkers

Cancer Biomarkers
  • Author : Institute of Medicine,Committee on Developing Biomarker-Based Tools for Cancer Screening, Diagnosis, and Treatment
  • Publisher : National Academies Press
  • Release : 27 March 2007
GET THIS BOOKCancer Biomarkers

Many cancer patients are diagnosed at a stage in which the cancer is too far advanced to be cured, and most cancer treatments are effective in only a minority of patients undergoing therapy. Thus, there is tremendous opportunity to improve the outcome for people with cancer by enhancing detection and treatment approaches. Biomarkers will be instrumental in making that transition. Advances in biotechnology and genomics have given scientists new hope that biomarkers can be used to improve cancer screening and

Design and Prototyping of a Non-faradaic Impedance Spectroscopy System for Clinical Diagnostics

Design and Prototyping of a Non-faradaic Impedance Spectroscopy System for Clinical Diagnostics
  • Author : Anjan Panneer Selvam
  • Publisher : Unknown Publisher
  • Release : 21 January 2022
GET THIS BOOKDesign and Prototyping of a Non-faradaic Impedance Spectroscopy System for Clinical Diagnostics

This dissertation presents the design of a label-free non-faradaic electrical impedance system for the detection of multiple types of biomarkers from physiological fluids at clinically relevant concentration for early disease diagnosis and prognosis. Biomarkers are important cues that reflect internal cellular and macromolecular states. Biomarkers can be both genetic and proteomic or other analyte types as well. While optical label-based sensors are ubiquitous in clinics and laboratories, they are not suited for portable and point-of-care environments. Traditional impedance biosensors are

Detection of CD4 and CD8 T-lymphocytes and HER2 Breast Cancer Biomarker Using the Opto-fluidic Ring Resonator Biosensor

Detection of CD4 and CD8 T-lymphocytes and HER2 Breast Cancer Biomarker Using the Opto-fluidic Ring Resonator Biosensor
  • Author : John Thomas Gohring
  • Publisher : Unknown Publisher
  • Release : 21 January 2022
GET THIS BOOKDetection of CD4 and CD8 T-lymphocytes and HER2 Breast Cancer Biomarker Using the Opto-fluidic Ring Resonator Biosensor

We have demonstrated label-free detection of CD4+ and CD8+ T-Lymphocytes and HER2 breast cancer biomarker using the opto-fluidic ring resonator (OFRR) sensor. The OFRR sensing platform incorporates microfluidics and photonics in a setup that utilizes small sample volume and achieves a fast detection time. For T-Lymphocyte cell detection, white blood cells were isolated from healthy blood and the concentrations adjusted to match T-Lymphocyte levels of individuals infected with HIV. Detection was accomplished by immobilizing CD4 and CD8 antibodies on the