The Molecular and Clinical Pathology of Neurodegenerative Disease

The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a unique perspective in relating clinical experiences with the molecular understanding needed to examine these diseases and is a must-read for anyone who wants to learn more about neurodegeneration. Provides an up-to-date summary of neurodegeneration at a molecular, cellular, and tissue level for the most common human disorders Describes the clinical background and underlying molecular processes for Alzheimer’s disease, Parkinson’s, Prion, Motor Neuron, Huntington’s, and Multiple Sclerosis Highlights the state-of-the-art treatment options for each disorder Details examples of relevant cutting edge experimental systems, including genome editing and human pluripotent stem cell-derived neuronal models

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  • Author : Patrick A. Lewis
  • Publisher : Academic Press
  • Pages : 274 pages
  • ISBN : 0128110708
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKThe Molecular and Clinical Pathology of Neurodegenerative Disease

The Molecular and Clinical Pathology of Neurodegenerative Disease

The Molecular and Clinical Pathology of Neurodegenerative Disease
  • Author : Patrick A. Lewis,Jennifer E. Spillane
  • Publisher : Academic Press
  • Release : 16 November 2018
GET THIS BOOKThe Molecular and Clinical Pathology of Neurodegenerative Disease

The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a

The Molecular Pathology of Neurodegenerative Disease

The Molecular Pathology of Neurodegenerative Disease
  • Author : Patrick A. Lewis,Jennifer E. Spillane
  • Publisher : Academic Press
  • Release : 15 October 2018
GET THIS BOOKThe Molecular Pathology of Neurodegenerative Disease

The Molecular Pathology of Neurodegenerative Disease brings together the current understanding of the molecular basis of neurodegeneration in humans in a form that is targeted not only for neuroscientists, but also for graduate students in neuroscience and the biomedical and biological sciences. There are a large number of existing books covering this subject that are aimed at a clinical audience (both at undergraduate and higher level), however the increasing interest in neurodegeneration for more basic science courses - neuroscientists, biologists,

The Molecular and Cellular Basis of Neurodegenerative Diseases

The Molecular and Cellular Basis of Neurodegenerative Diseases
  • Author : Michael S. Wolfe
  • Publisher : Academic Press
  • Release : 29 March 2018
GET THIS BOOKThe Molecular and Cellular Basis of Neurodegenerative Diseases

The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : Philip Beart,Michael Robinson,Marcus Rattray,Nicholas J. Maragakis
  • Publisher : Springer
  • Release : 21 July 2017
GET THIS BOOKNeurodegenerative Diseases

Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies. The editors bring together contributions from internationally recognized workers in the field to provide an up to date account of how and why molecular and cellular neurobiology is such an important area for clinical neuroscience. Understanding the molecular aspects of a number of neurodegenerative conditions such

Neurodegeneration

Neurodegeneration
  • Author : Dennis Dickson,Roy O. Weller
  • Publisher : John Wiley & Sons
  • Release : 09 September 2011
GET THIS BOOKNeurodegeneration

Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within

Molecular Mechanisms of Neurodegenerative Diseases

Molecular Mechanisms of Neurodegenerative Diseases
  • Author : Marie-Francoise Chesselet
  • Publisher : Springer Science & Business Media
  • Release : 19 October 2000
GET THIS BOOKMolecular Mechanisms of Neurodegenerative Diseases

With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better understanding of the molecular and cellular mechanisms leading to neurodegeneration. In Molecular Mechanisms of Neurodegenerative Diseases, Marie-Francoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from

Molecular Biology of Neurodegenerative Diseases

Molecular Biology of Neurodegenerative Diseases
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 22 May 2012
GET THIS BOOKMolecular Biology of Neurodegenerative Diseases

Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning. Examples include Parkinson’s, Alzheimer’s and Huntington’s disease. Much research is taking place to try to identify ways to prevent or lessen the impact of these diseases. This volume reviews the latest research and developments in the molecular biology of neurodegenerative diseases. Contributions from leading authorities Informs and updates on all the latest developments in the field

Parkinson's Disease

Parkinson's Disease
  • Author : Patrik Verstreken
  • Publisher : Academic Press
  • Release : 19 December 2016
GET THIS BOOKParkinson's Disease

Parkinson’s Disease: Molecular Mechanisms Underlying Pathology explores the molecular pathways at the basis of the cellular defects connected to Parkinson’s disease, the second most common neurodegenerative disease, and the most common movement disorder. This book presents the latest research on the pathways and mechanisms that have been discovered to play a role in Parkinson's pathology. This focus on mechanisms rather than individual genes allows the contributors to elaborate on overlapping and joint functions of different causative genes. Readers

Pathology, Prevention and Therapeutics of Neurodegenerative Disease

Pathology, Prevention and Therapeutics of Neurodegenerative Disease
  • Author : Sarika Singh,Neeraj Joshi
  • Publisher : Springer
  • Release : 24 September 2018
GET THIS BOOKPathology, Prevention and Therapeutics of Neurodegenerative Disease

This book, written by a leading panel of experts in the field of neurosciences, provides a comprehensive overview of the pathology of neurodegenerative diseases as well as the preventive measures. Prevention is important due to the lack of early diagnostic markers and the limitations/ problems of treating neurodegenerative diseases

Biometals in Neurodegenerative Diseases

Biometals in Neurodegenerative Diseases
  • Author : Anthony R. White,Michael Aschner,Lucio G. Costa,Ashley I. Bush
  • Publisher : Academic Press
  • Release : 28 April 2017
GET THIS BOOKBiometals in Neurodegenerative Diseases

Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or

Metabolic and Bioenergetic Drivers of Neurodegenerative Disease: Treating Neurodegenerative Diseases as Metabolic Diseases

Metabolic and Bioenergetic Drivers of Neurodegenerative Disease: Treating Neurodegenerative Diseases as Metabolic Diseases
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 01 September 2020
GET THIS BOOKMetabolic and Bioenergetic Drivers of Neurodegenerative Disease: Treating Neurodegenerative Diseases as Metabolic Diseases

Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease reviews how the different aspects of metabolic dysfunction and consequent pathology associated with neurodegenerative diseases, including Alzheimer’s and Parkinson’s, can be targeted by novel treatment approaches. Topics covered include Cellular Senescence in Aging and Age-Related Disorders: Implications for Neurodegenerative Diseases; Repurposing GLP1 agonists for Neurodegenerative Diseases; Ketotherapeutics for Neurodegenerative Diseases; Enhancing Mitophagy as a Therapeutic Approach for Neurodegenerative Diseases; Harnessing Neurogenesis in the Adult Brain – A Role in Type 2 Diabetes

Neuropathology of Neurodegenerative Diseases

Neuropathology of Neurodegenerative Diseases
  • Author : Gabor G. Kovacs
  • Publisher : Cambridge University Press
  • Release : 28 December 2017
GET THIS BOOKNeuropathology of Neurodegenerative Diseases

This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of

Glutamine Repeats and Neurodegenerative Diseases

Glutamine Repeats and Neurodegenerative Diseases
  • Author : Peter S. Harper,Max F. Perutz
  • Publisher : Oxford University Press, USA
  • Release : 19 October 2021
GET THIS BOOKGlutamine Repeats and Neurodegenerative Diseases

This book focuses on the discovery of a common genetic basis for a group of inherited neurological disorders including Huntington's Disease, spino-bulbar muscular atrophy and a series of hereditary ataxias. It now seems likely that these disorders are triggered by expanded trinucleotide repeats resulting in polyglutamine sequences in the specific proteins produced by the genes. This shared molecular background and other similarities, have led to the development of theoretical models for the pathogenesis of these diseases. It is now clear