The Organic Chemistry of Drug Design and Drug Action

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

Produk Detail:

  • Author : Richard B. Silverman
  • Publisher : Elsevier
  • Pages : 617 pages
  • ISBN : 0080513379
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKThe Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action
  • Author : Richard B. Silverman
  • Publisher : Elsevier
  • Release : 02 December 2012
GET THIS BOOKThe Organic Chemistry of Drug Design and Drug Action

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action
  • Author : Richard B. Silverman
  • Publisher : Elsevier
  • Release : 02 December 2012
GET THIS BOOKThe Organic Chemistry of Drug Design and Drug Action

This is a new approach to the teaching of medicinal chemistry. The knowledge of the physical organic chemical basis of drug design and drug action allows the reader to extrapolate to the many related classes of drugs described in standard medicinal chemistry texts. Students gain a solid foundation to base future research endeavors upon: drugs not yet developed are thus covered! n Emphasizes the use of the principles of physical organic chemistry as a basis for drug design n Discusses

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action
  • Author : Richard B. Silverman
  • Publisher : Academic Press
  • Release : 26 January 2004
GET THIS BOOKThe Organic Chemistry of Drug Design and Drug Action

Standard medicinal texts are organized by classes of drugs with an emphasis on descriptions of their pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that rationalized drug action and allows the reader to extrapolate to many related classed of drug molecules.

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action
  • Author : Richard B. Silverman,Mark W. Holladay
  • Publisher : Academic Press
  • Release : 29 March 2014
GET THIS BOOKThe Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach

Chemistry and Molecular Aspects of Drug Design and Action

Chemistry and Molecular Aspects of Drug Design and Action
  • Author : E. A. Rekka,P. N. Kourounakis
  • Publisher : CRC Press
  • Release : 28 April 2008
GET THIS BOOKChemistry and Molecular Aspects of Drug Design and Action

An ever-increasing demand for better drugs, elevated safety standards, and economic considerations have all led to a dramatic paradigm shift in the way that drugs are being discovered and developed. Known as rational drug design, this contemporary process is defined by three main steps: the discovery of lead compounds, surgical manipulation to deve

The Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry
  • Author : Camille Georges Wermuth,David Aldous,Pierre Raboisson,Didier Rognan
  • Publisher : Elsevier
  • Release : 01 July 2015
GET THIS BOOKThe Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to

An Introduction to Medicinal Chemistry

An Introduction to Medicinal Chemistry
  • Author : Graham L. Patrick
  • Publisher : Oxford University Press, USA
  • Release : 28 October 2021
GET THIS BOOKAn Introduction to Medicinal Chemistry

NEW TO THIS EDITION Updated throughout with the latest descoveries Five new chapters covering * the molecular structure of receptors and the mechanisms of signal transduction *combinatorial synthesis * the role of computers in drug design * adrenergics * drug discovery and drug development

Chirality in Drug Design and Synthesis

Chirality in Drug Design and Synthesis
  • Author : C. Brown
  • Publisher : Academic Press
  • Release : 22 October 2013
GET THIS BOOKChirality in Drug Design and Synthesis

Chirality in Drug Design and Synthesis is a collection of papers that discusses the property of asymmetry in the structural and synthetic chemistry of natural products, including the significance of chirality in medicinal chemistry. These papers examine the need for the preparation and study of pure enantiomers of chiral drug substances and their mechanism of interaction with enzymes and receptors. These papers also investigate the techniques in studying these interactions, as well as analyze the methods for their synthesis in

Small Molecule Drug Discovery

Small Molecule Drug Discovery
  • Author : Andrea Trabocchi,Elena Lenci
  • Publisher : Elsevier
  • Release : 23 November 2019
GET THIS BOOKSmall Molecule Drug Discovery

Small Molecule Drug Discovery: Methods, Molecules and Applications presents the methods used to identify bioactive small molecules, synthetic strategies and techniques to produce novel chemical entities and small molecule libraries, chemoinformatics to characterize and enumerate chemical libraries, and screening methods, including biophysical techniques, virtual screening and phenotypic screening. The second part of the book gives an overview of privileged cyclic small molecules and major classes of natural product-derived small molecules, including carbohydrate-derived compounds, peptides and peptidomimetics, and alkaloid-inspired compounds. The

Drug Design and Medicinal Chemistry

Drug Design and Medicinal Chemistry
  • Author : Erica Helmer
  • Publisher : Unknown Publisher
  • Release : 31 March 2015
GET THIS BOOKDrug Design and Medicinal Chemistry

This book covers the different aspects of drug design and medicinal chemistry. Recently, medicinal chemistry has become accountable for clarifying interactions of chemical molecules procedures, such that many experts in life sciences, from agronomy to medication, are occupied in medicinal study. This book comprises of researches centering on molecular features of drug metabolism, pro-drug production, in silico and chemical compounds used in applicable methods. It even deals with fundamental issues and developments in medicinal chemistry and drug design. Particular significance

Textbook of Drug Design and Discovery, Third Edition

Textbook of Drug Design and Discovery, Third Edition
  • Author : Tommy Liljefors,Povl Krogsgaard-Larsen,Ulf Madsen
  • Publisher : CRC Press
  • Release : 25 July 2002
GET THIS BOOKTextbook of Drug Design and Discovery, Third Edition

Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Green Approaches in Medicinal Chemistry for Sustainable Drug Design
  • Author : Bimal K. Banik
  • Publisher : Elsevier
  • Release : 27 March 2020
GET THIS BOOKGreen Approaches in Medicinal Chemistry for Sustainable Drug Design

Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and

Medicinal Chemistry

Medicinal Chemistry
  • Author : C. R. Ganellin,Stanley M. Roberts
  • Publisher : Academic Press
  • Release : 12 March 1993
GET THIS BOOKMedicinal Chemistry

This new edition aims to introduce students to the mechanisms of action of drugs and the approaches adopted in designing new drugs. It also contains chapters on individual successful drugs written by their discoverers or developers, tracing their history to the present day.