Translating Gene Therapy to the Clinic

Translating Gene Therapy to the Clinic, edited by Dr. Jeffrey Laurence and Michael Franklin, follows the recent, much-lauded special issue of Translational Research in emphasizing clinical milestones and critical barriers to further progress in the clinic. This comprehensive text provides a background for understanding the techniques involved in human gene therapy trials, and expands upon the disease-specific situations in which these new approaches currently have the greatest therapeutic application or potential, and those areas most in need of future research. It emphasizes methods, tools, and experimental approaches used by leaders in the field of translational gene therapy. The book promotes cross-disciplinary communication between the sub-specialties of medicine, and remains unified in theme. Presents impactful and widely supported research across the spectrum of science, method, implementation and clinical application Offers disease-based coverage from expert clinician-scientists, covering everything from arthritis to congestive heart failure, as it details specific progress and barriers for current translational use Provides key background information from immune response through genome engineering and gene transfer, relevant information for practicing clinicians contemplating enrolling patients in gene therapy trials

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  • Author : Jeffrey Laurence
  • Publisher : Academic Press
  • Pages : 346 pages
  • ISBN : 0128005645
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKTranslating Gene Therapy to the Clinic

Translating Gene Therapy to the Clinic

Translating Gene Therapy to the Clinic
  • Author : Jeffrey Laurence,Michael Franklin
  • Publisher : Academic Press
  • Release : 14 November 2014
GET THIS BOOKTranslating Gene Therapy to the Clinic

Translating Gene Therapy to the Clinic, edited by Dr. Jeffrey Laurence and Michael Franklin, follows the recent, much-lauded special issue of Translational Research in emphasizing clinical milestones and critical barriers to further progress in the clinic. This comprehensive text provides a background for understanding the techniques involved in human gene therapy trials, and expands upon the disease-specific situations in which these new approaches currently have the greatest therapeutic application or potential, and those areas most in need of future research.

Translating Regenerative Medicine to the Clinic

Translating Regenerative Medicine to the Clinic
  • Author : Jeffrey Laurence,Pedro Baptista,Anthony Atala
  • Publisher : Academic Press
  • Release : 18 November 2015
GET THIS BOOKTranslating Regenerative Medicine to the Clinic

Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent

Gene Therapy

Gene Therapy
  • Author : Kam M. Hui
  • Publisher : World Scientific
  • Release : 05 July 1994
GET THIS BOOKGene Therapy

With advances in our understanding of the molecular biology of human diseases and the development of efficient gene transfer techniques, the treatment of such diseases as cancer and infectious disease using gene therapy has progressed from a distant prospect to a distinct possibility in a very short time. The development of gene transfer methods which are suitable for different forms of therapy has been a major topic of research over the past several years. A common goal of this research

Translating MicroRNAs to the Clinic

Translating MicroRNAs to the Clinic
  • Author : Jeffrey Laurence
  • Publisher : Academic Press
  • Release : 17 September 2016
GET THIS BOOKTranslating MicroRNAs to the Clinic

Translating microRNA to the Clinic reviews the possibilities of current methodological tools and experimental approaches used by leading translational researchers. The book features the uses of micro ribonucleic acid as deployed in cancer targeting in biomarkers, diabetes, cardiovascular disease, and neurodegeneration, among many others. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field, promoting a cross-disciplinary communication between the sub-specialities of medicine, but in common with other books

Molecular Biology of Cancer: Translation to the Clinic

Molecular Biology of Cancer: Translation to the Clinic
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 16 December 2010
GET THIS BOOKMolecular Biology of Cancer: Translation to the Clinic

Advances in molecular biology over the last several decades are being steadily applied to our understanding of the molecular biology of cancer, and these advances in knowledge are being translated into the clinical practice of oncology. This volume explores some of the most exciting recent advances in basic research on the molecular biology of cancer and how this knowledge is leading to advances in the diagnosis, treatment, and prevention of cancer. * This series provides a forum for discussion of new

Translational Neuroscience

Translational Neuroscience
  • Author : Mark H. Tuszynski
  • Publisher : Springer
  • Release : 08 March 2016
GET THIS BOOKTranslational Neuroscience

Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology, neuro devices, rehabilitation and others over the last 20 years have generated unprecedented opportunities to treat heretofore untreatable disorders of the nervous system. This book provides a wide-ranging

From Research to Reality

From Research to Reality
  • Author : The Expert Panel on the Approval and Use of Somatic Gene Therapies in Canada
  • Publisher : Council of Canadian Academies
  • Release : 05 November 2020
GET THIS BOOKFrom Research to Reality

From Research to Reality describes the stages involved in the approval and use of gene therapies in Canada, and examines challenges associated with regulatory oversight, manufacturing, access, and affordability, and identifies promising approaches to address them.

Drug Delivery to the Brain

Drug Delivery to the Brain
  • Author : Elizabeth C.M. de Lange,Margareta Hammarlund-Udenaes,Robert G. Thorne
  • Publisher : Springer Nature
  • Release : 24 May 2022
GET THIS BOOKDrug Delivery to the Brain

The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood–brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics

Animal Models of Molecular Pathology

Animal Models of Molecular Pathology
  • Author : P. Michael Conn
  • Publisher : Academic Press
  • Release : 26 November 2011
GET THIS BOOKAnimal Models of Molecular Pathology

This volume explores some of the most exciting recent advances in basic research on animal models of molecular pathology. This series provides a forum for discussion of new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields

Epidemiology of Endocrine Tumors

Epidemiology of Endocrine Tumors
  • Author : Jahangir Moini,Craig Badolato,Raheleh Ahangari
  • Publisher : Elsevier
  • Release : 17 February 2021
GET THIS BOOKEpidemiology of Endocrine Tumors

Epidemiology of Endocrine Tumors brings current data and clinical research into one source for a multidisciplinary audience. The book discusses the prevalence, incidence, etiology, pathology, diagnosis and treatment of various endocrine tumors. With clear and focused writing, it is essential reading for healthcare professionals, endocrinologists, oncologists, and public health professionals. Users will be able to bridge the knowledge gap that exists in the comprehensive coverage surrounding the epidemiology of endocrine tumors. Globally, the prevalence and incidence of endocrine tumors is

Gene Therapy for Cancer

Gene Therapy for Cancer
  • Author : Kelly K. Hunt,Stephan A. Vorburger,Stephen G. Swisher
  • Publisher : Springer Science & Business Media
  • Release : 26 October 2007
GET THIS BOOKGene Therapy for Cancer

The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment for cancer to the clinic. This book will prove valuable as the volume of preclinical and clinical data continues to increase.

A Guide to Human Gene Therapy

A Guide to Human Gene Therapy
  • Author : Roland W. Herzog,Sergei Zolotukhin
  • Publisher : World Scientific
  • Release : 05 July 2022
GET THIS BOOKA Guide to Human Gene Therapy

Ever since the birth of molecular biology, the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy - though still in its infancy - remains one of the hottest areas of research in medicine. Its approach utilizes a gene transfer vehicle ( vector) to deliver therapeutic DNA or RNA to cells of the body in order to rectify the defect that is causing the disease. Successful therapies have been reported in humans in recent years

Gene Delivery

Gene Delivery
  • Author : Yashwant Pathak
  • Publisher : CRC Press
  • Release : 29 June 2022
GET THIS BOOKGene Delivery

Gene delivery is a transport of genes of therapeutic values into the chromosomes of the cells or tissues which can be targeted to replace the faulty genes. In last two decades lot of research efforts are dedicated to gene delivery for therapeutic applications. Today gene therapy is promising approach in treatment of genetic diseases including mitochondrial related diseases like blindness, muscular dystrophy, cystic fibrosis, and some cancers. Gene Delivery Systems: Nano Delivery Technologies observes the exploration of nanotechnology for gene