Translating MicroRNAs to the Clinic

Translating microRNA to the Clinic reviews the possibilities of current methodological tools and experimental approaches used by leading translational researchers. The book features the uses of micro ribonucleic acid as deployed in cancer targeting in biomarkers, diabetes, cardiovascular disease, and neurodegeneration, among many others. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field, promoting a cross-disciplinary communication between the sub-specialities of medicine, but in common with other books on the topic. In addition, the book emphasizes recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Encompasses the latest innovations and tools being used to apply microRNA from lab to clinic“/li> Extensive pedagogical updates aiming to improve the education of translational researchers in this field Transdisciplinary approach aims to support cross-fertilization between different sub-specialties of medicine

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  • Author : Jeffrey Laurence
  • Publisher : Academic Press
  • Pages : 392 pages
  • ISBN : 0128005548
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKTranslating MicroRNAs to the Clinic

Translating MicroRNAs to the Clinic

Translating MicroRNAs to the Clinic
  • Author : Jeffrey Laurence
  • Publisher : Academic Press
  • Release : 17 September 2016
GET THIS BOOKTranslating MicroRNAs to the Clinic

Translating microRNA to the Clinic reviews the possibilities of current methodological tools and experimental approaches used by leading translational researchers. The book features the uses of micro ribonucleic acid as deployed in cancer targeting in biomarkers, diabetes, cardiovascular disease, and neurodegeneration, among many others. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field, promoting a cross-disciplinary communication between the sub-specialities of medicine, but in common with other books

Translating Regenerative Medicine to the Clinic

Translating Regenerative Medicine to the Clinic
  • Author : Jeffrey Laurence,Pedro Baptista,Anthony Atala
  • Publisher : Academic Press
  • Release : 18 November 2015
GET THIS BOOKTranslating Regenerative Medicine to the Clinic

Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent

Translating Gene Therapy to the Clinic

Translating Gene Therapy to the Clinic
  • Author : Jeffrey Laurence,Michael Franklin
  • Publisher : Academic Press
  • Release : 14 November 2014
GET THIS BOOKTranslating Gene Therapy to the Clinic

Translating Gene Therapy to the Clinic, edited by Dr. Jeffrey Laurence and Michael Franklin, follows the recent, much-lauded special issue of Translational Research in emphasizing clinical milestones and critical barriers to further progress in the clinic. This comprehensive text provides a background for understanding the techniques involved in human gene therapy trials, and expands upon the disease-specific situations in which these new approaches currently have the greatest therapeutic application or potential, and those areas most in need of future research.

Translating Epigenetics to the Clinic

Translating Epigenetics to the Clinic
  • Author : Jeffrey Laurence
  • Publisher : Academic Press
  • Release : 30 December 2016
GET THIS BOOKTranslating Epigenetics to the Clinic

Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes, as well as the ‘diseases of modernity’—including pharmacological addiction, dementia, and ageing. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders

RNA Delivery Function for Anticancer Therapeutics

RNA Delivery Function for Anticancer Therapeutics
  • Author : Loutfy H. Madkour
  • Publisher : CRC Press
  • Release : 26 January 2022
GET THIS BOOKRNA Delivery Function for Anticancer Therapeutics

This book presents an overview of the current status of translating the RNAi cancer therapeutics in the clinic, a brief description of the biological barriers in drug delivery, and the roles of imaging in aspects of administration route, systemic circulation, and cellular barriers for the clinical translation of RNAi cancer therapeutics, and with partial content for discussing the safety concerns. It then focuses on imaging-guided delivery of RNAi therapeutics in preclinical development, including the basic principles of different imaging modalities,

AGO-Driven Non-Coding RNAs

AGO-Driven Non-Coding RNAs
  • Author : Bibekanand Mallick
  • Publisher : Academic Press
  • Release : 20 January 2019
GET THIS BOOKAGO-Driven Non-Coding RNAs

The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years,

MicroRNA in Human Malignancies

MicroRNA in Human Malignancies
  • Author : Massimo Negrini,George A. Calin,Carlo M. Croce
  • Publisher : Academic Press
  • Release : 18 February 2022
GET THIS BOOKMicroRNA in Human Malignancies

MicroRNA in Human Malignancies offers a deep overview of the role and translational significance of miRNAs in the development of cancer and other malignancies. The book establishes the foundations of the field by covering essential mechanisms and the translational potential of miRNAs in the field of oncology. Specific topics covered include invasion and metastasis, miRNAs and metabolism, and opportunities of miRNAs in therapeutics. Chapters on diseases include content on disease-related pathophysiology, as well as diagnostic, prognostic and predictive value. This

Hepatitis C

Hepatitis C
  • Author : Imran Shahid
  • Publisher : BoD – Books on Demand
  • Release : 10 October 2018
GET THIS BOOKHepatitis C

The propagation of hepatitis C from acute to chronic infection and afterward to end-stage liver diseases (hepatic fibrosis, cirrhosis, and hepatocellular carcinoma) involves a highly orchestrated series of molecular and cellular events, including a plethora of genes and cell signaling cascades. The treatment paradigms was revolutionized after the development and approval of all oral interferon-free direct-acting antivirals achieving higher sustained virologic response rates in treated individuals. This book pragmatically overviews the intricate interplay between viral and host factors during hepatitis

Biomedical Applications of Microfluidic Devices

Biomedical Applications of Microfluidic Devices
  • Author : Michael R. Hamblin,Mahdi Karimi
  • Publisher : Academic Press
  • Release : 12 November 2020
GET THIS BOOKBiomedical Applications of Microfluidic Devices

Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a

MicroRNAs in Diseases and Disorders

MicroRNAs in Diseases and Disorders
  • Author : Philip V Peplow,Bridget Martinez,George A Calin,Aurora Esquela-Kerscher
  • Publisher : Royal Society of Chemistry
  • Release : 07 May 2019
GET THIS BOOKMicroRNAs in Diseases and Disorders

From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive account, this book also includes the identification of miRNAs as diagnostic and prognostic biomarkers for disease, as well as evaluates translational value from clinical trials using synthesized and functionalized miRNA

MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets

MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets
  • Author : Philip V Peplow,Bridget Martinez,George A Calin,Aurora Esquela-Kerscher
  • Publisher : Royal Society of Chemistry
  • Release : 21 May 2019
GET THIS BOOKMicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets

From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive account, this book also includes the identification of miRNAs as diagnostic and prognostic biomarkers for disease, as well as evaluates translational value from clinical trials using synthesized and functionalized miRNA

Tumor Liquid Biopsies

Tumor Liquid Biopsies
  • Author : Florence Schaffner,Jean-Louis Merlin,Nikolas von Bubnoff
  • Publisher : Springer Nature
  • Release : 11 October 2019
GET THIS BOOKTumor Liquid Biopsies

This book is a comprehensive guide to the techniques, clinical applications, and benefits of the different forms of liquid biopsy employed in patients with a variety of tumor types, including lung, breast and colorectal cancer. Offering detailed explanations, it discusses the how changes in tumors can be tracked using these cutting-edge technologies, which enable the detection and analysis of diverse circulating biomarkers: tumor cells, tumor DNA, tumor RNA (free or in exosomes), and fluid biomarkers identifiable by means of targeted

MicroRNA Cancer Regulation

MicroRNA Cancer Regulation
  • Author : Ulf Schmitz,Olaf Wolkenhauer,Julio Vera
  • Publisher : Springer Science & Business Media
  • Release : 03 February 2013
GET THIS BOOKMicroRNA Cancer Regulation

This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and applications, together with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. We are sure that the emergence of high-throughput quantitative techniques will make this integrative approach absolutely necessary in the near future. This book will be a resource for researchers starting out with

Precision Cancer Medicine

Precision Cancer Medicine
  • Author : Sameek Roychowdhury,Eliezer M. Van Allen
  • Publisher : Springer Nature
  • Release : 02 January 2020
GET THIS BOOKPrecision Cancer Medicine

Genomic sequencing technologies have augmented the classification of cancer beyond tissue of origin and towards a molecular taxonomy of cancer. This has created opportunities to guide treatment decisions for individual patients with cancer based on their cancer’s unique molecular characteristics, also known as precision cancer medicine. The purpose of this text will be to describe the contribution and need for multiple disciplines working together to deliver precision cancer medicine. This entails a multi-disciplinary approach across fields including molecular pathology,