Translational Advances in Gynecologic Cancers

Translational Advances in Gynecologic Cancers straddles the bench and bed divide by highlighting important and interesting research that is translatable to the clinic. The contents of this book cover the entire spectrum, from promising laboratory based research, to clinical trial efforts. Further, new therapeutic indications based upon randomized phase III trials are also included. Clinicians will learn about lab-based science that is about to enter the clinic, along with the rationale behind translational endpoints in trials. Researchers will be able to identify and understand the clinical needs of patients with these types of tumors to improve their research focus. Provides a comprehensive description of all evolving translational gynecologic cancer research for clinicians Identifies knowledge gaps to inform the next research direction Ties together clinical research and patient needs to help both the researcher and clinician Addresses genomics, new target therapies, novel tools, and more for ovarian, endometrial, and cervical cancer

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  • Author : Michael Birrer
  • Publisher : Academic Press
  • Pages : 354 pages
  • ISBN : 0128037989
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKTranslational Advances in Gynecologic Cancers

Translational Advances in Gynecologic Cancers

Translational Advances in Gynecologic Cancers
  • Author : Michael Birrer,Lorenzo Ceppi
  • Publisher : Academic Press
  • Release : 25 January 2017
GET THIS BOOKTranslational Advances in Gynecologic Cancers

Translational Advances in Gynecologic Cancers straddles the bench and bed divide by highlighting important and interesting research that is translatable to the clinic. The contents of this book cover the entire spectrum, from promising laboratory based research, to clinical trial efforts. Further, new therapeutic indications based upon randomized phase III trials are also included. Clinicians will learn about lab-based science that is about to enter the clinic, along with the rationale behind translational endpoints in trials. Researchers will be able

Molecular Diagnosis and Targeting for Gynecologic Malignancy

Molecular Diagnosis and Targeting for Gynecologic Malignancy
  • Author : Seiji Isonishi,Yoshihiro Kikuchi
  • Publisher : Springer
  • Release : 06 March 2021
GET THIS BOOKMolecular Diagnosis and Targeting for Gynecologic Malignancy

This book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding of gynecologic cancer biology, prevention and treatment, and drug response and resistance. Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with

Applications of NMR Spectroscopy: Volume 8

Applications of NMR Spectroscopy: Volume 8
  • Author : Atta-ur-Rahman,M. Iqbal Choudhary
  • Publisher : Bentham Science Publishers
  • Release : 02 October 2020
GET THIS BOOKApplications of NMR Spectroscopy: Volume 8

Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture. The eighth volume of the series features six reviews focusing on NMR spectroscopic techniques in food science, molecular biology and medical diagnosis. The reviews in this volume are: - qNMR as a Tool for Determination of Six Common Sugars in Foods - Correlation of VIP Scores and 1

Molecular Oncology: Underlying Mechanisms and Translational Advancements

Molecular Oncology: Underlying Mechanisms and Translational Advancements
  • Author : Ammad Ahmad Farooqi,Muhammad Ismail
  • Publisher : Springer
  • Release : 29 March 2017
GET THIS BOOKMolecular Oncology: Underlying Mechanisms and Translational Advancements

Cancer is a multifaceted and genomically complex disease and data obtained through high throughput technologies has provided near complete resolution of the landscape of how genomic, genetic and epigenetic mutations in cancerous cells effectively influence homeostasis of signaling networks within these cells, between cancerous cells, tumor microenvironment and at the organ level. Increasingly sophisticated information has helped us in developing a better understanding of the underlying mechanisms of cancer, and it is now known that intra-tumor genetic heterogeneity, cellular plasticity,

Endometrial Cancer

Endometrial Cancer
  • Author : Ivan Diaz-padilla,Jesus Garcia-donas
  • Publisher : Unknown Publisher
  • Release : 01 January 2014
GET THIS BOOKEndometrial Cancer

Endometrial cancer is the most common gynecological malignancy in women in developed countries. Most cases are generally diagnosed at an early-stage and curable with loco-regional therapies. Metastatic and/or recurrent disease still remains a therapeutic challenge and clearly represents an unmet medical need. Substantial progress has been made over the last decade in different fields of Gynecologic Oncology that has translated into a better understanding of the biology and clinical behavior of endometrial cancer and its management. Hence, this monograph

Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing

Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing
  • Author : Khalid El Bairi
  • Publisher : Springer Nature
  • Release : 28 September 2020
GET THIS BOOKIlluminating Colorectal Cancer Genomics by Next-Generation Sequencing

This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers. It critically discusses findings from recent large-scale studies, clinical trials and meta-analyses and offers an introduction to the management of CRC in the era of precision medicine. In CRC, dozens of driver and passenger mutations are associated with the malignant transformation of epithelial cells. Consequently, the

Translation and Its Regulation in Cancer Biology and Medicine

Translation and Its Regulation in Cancer Biology and Medicine
  • Author : Armen Parsyan
  • Publisher : Springer
  • Release : 13 October 2014
GET THIS BOOKTranslation and Its Regulation in Cancer Biology and Medicine

This book, for the first time, comprehensively assembles and analyzes a large body of information on the role of the fundamental mechanism of the protein biosynthesis pathway, translation, in cancer biology. It systematically explores the function of the translation machinery and its regulation, including cell signaling, in the development, maintenance and progression of human cancer. The work presented here unveils the tremendous potential and applications of this vast and exciting branch of genetic, biochemical and molecular science in cancer medicine

Noninvasive Molecular Markers in Gynecologic Cancers

Noninvasive Molecular Markers in Gynecologic Cancers
  • Author : Debmalya Barh,Mehmet Gunduz
  • Publisher : CRC Press
  • Release : 22 January 2015
GET THIS BOOKNoninvasive Molecular Markers in Gynecologic Cancers

Early detection is critical for any given cancer. With the advent of the latest omics technologies, molecular markers in combination with conventional diagnostic and screening methods are emerging as next-generation early diagnostic and prognostic strategies that can allow early-stage diagnosis, resulting in more effective treatment and patient car

Gynecologic Cancers

Gynecologic Cancers
  • Author : Kunle Odunsi, MD,Tanja Pejovic, MD
  • Publisher : Demos Medical Publishing
  • Release : 09 October 2013
GET THIS BOOKGynecologic Cancers

Over the course of the last decade, the treatment of gynecologic cancer has evolved quite rapidly. New scientific and clinical advances have modified the standard of care and led to improved patient outcomes. At the same time, the treatment of gynecologic cancer has become increasingly complex, requiring the comprehensive review and assessment of multiple issues including genetics, radiology, surgery, molecular diagnostics, chemotherapy, and more. As a result, the harmony and open communication between these specialties facilitated by a multidisciplinary team

Hormone Receptors in Breast Cancer

Hormone Receptors in Breast Cancer
  • Author : Suzanne A. W. Fuqua
  • Publisher : Springer Science & Business Media
  • Release : 10 December 2008
GET THIS BOOKHormone Receptors in Breast Cancer

Hormone Receptors in Breast Cancer provides an up-to-date resource of the role of hormone receptors in breast cancer written in depth for both the basic molecular academic researcher and translational scientist. Advances in basic science of molecular endocrinology have undoubtedly been translated into clinical practice, and clinicians caring for this disease need to be knowledgeable about these developments. The molecular basis of hormone action has been elucidated, and the relative significance of the different estrogen and progesterone receptor isoforms has

Ovarian Cancer

Ovarian Cancer
  • Author : Ivan Diaz-Padilla
  • Publisher : BoD – Books on Demand
  • Release : 27 February 2013
GET THIS BOOKOvarian Cancer

"Ovarian Cancer: A Clinical and Translational Update" embraces the most recent advances in diagnosis and treatment of ovarian cancer. With the valuable collaboration of international experts in the field, this book is intended to provide the readership with a comprehensive update in the subject of epithelial ovarian cancer.

Gynecological Cancers

Gynecological Cancers
  • Author : Antonio Giordano,Marcella Macaluso
  • Publisher : Springer
  • Release : 12 July 2016
GET THIS BOOKGynecological Cancers

Facilitating the collaboration between the basic, translational, and clinical sciences, this book provides an overview of the genetic and epigenetic mechanisms underlying the formation and progression of gynecological cancers. Gynecological Cancers: Genetic and Epigenetic Targets and Drug Development gathers all of the molecular and cellular aspects of gynecological cancer together within one volume, providing detailed and up-to-date information on the etiology, diagnosis, and treatment of gynecological cancers. Gynecological Cancers: Genetic and Epigenetic Targets and Drug Development ​also discusses the racial

Overcoming Drug Resistance in Gynecologic Cancers

Overcoming Drug Resistance in Gynecologic Cancers
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 20 August 2021
GET THIS BOOKOvercoming Drug Resistance in Gynecologic Cancers

Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and

Ovarian Cancers

Ovarian Cancers
  • Author : National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Care Services,Committee on the State of the Science in Ovarian Cancer Research
  • Publisher : National Academies Press
  • Release : 25 April 2016
GET THIS BOOKOvarian Cancers

In an era of promising advances in cancer research, there are considerable and even alarming gaps in the fundamental knowledge and understanding of ovarian cancer. Researchers now know that ovarian cancer is not a single disease-several distinct subtypes exist with different origins, risk factors, genetic mutations, biological behaviors, and prognoses. However, persistent questions have impeded progress toward improving the prevention, early detection, treatment, and management of ovarian cancers. Failure to significantly improve morbidity and mortality during the past several decades

Gynecologic Cancers

Gynecologic Cancers
  • Author : Samir Farghaly
  • Publisher : BoD – Books on Demand
  • Release : 02 March 2016
GET THIS BOOKGynecologic Cancers

Gynecologic cancers include malignancies of the female genital tract involving the vulva, vagina, cervix, uterus, fallopian tubes or ovaries. In the USA, 98,280 women had gynecological cancers in 2015, and 30,440 died of these cancers. World wide, the number of women who had cancers of the female genital tract was 1,085,900, in 2012 and the number of deaths was 417,600. Cancers of the uterus, cervix and ovary are most common. Widespread screening with the Pap test has allowed physicians to find per-cancerous changes in the cervix