Translational Cardiometabolic Genomic Medicine

Translational Cardiometabolic Genomic Medicine, edited by Dr. Annabelle Rodriguez-Oquendo, is an important resource to postgraduate (medical, dental and graduate) students, postdoctoral fellows, basic scientists, and physician scientists seeking to understand and expand their knowledge base in the field of genomic medicine as it is applied to cardiometabolic diseases. This handbook integrates cutting-edge experimental approaches such as chromatin immunoprecipitation paired end tagging (CHIA-PET), to population studies such as the Multi-Ethnic Study of Atherosclerosis. It encompasses a range of book chapters that highlight bioinformatic approaches to better understanding functionality of the noncoding regions of the human genome to the use of molecular diagnostic testing in predicting increased risk of cardiovascular diseases. Where applicable, this reference also includes chapters related to therapeutic options specifically aligned to molecular targets. Provides comprehensive research on translational genomic medicine Explains state-of-the-art genome editing for stem cells and mouse models with significant relevance to human cardiometabolic disease Includes discussions on the functional effects of single nucleotide polymorphisms and cardiometabolic diseases, stratified by sex and race Encompasses a range of book chapters that highlight bioinformatic approaches to better understanding functionality of the noncoding regions of the human genome

Produk Detail:

  • Author : Annabelle Rodriguez-Oquendo
  • Publisher : Academic Press
  • Pages : 352 pages
  • ISBN : 0128004746
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKTranslational Cardiometabolic Genomic Medicine

Translational Cardiometabolic Genomic Medicine

Translational Cardiometabolic Genomic Medicine
  • Author : Annabelle Rodriguez-Oquendo
  • Publisher : Academic Press
  • Release : 07 September 2015
GET THIS BOOKTranslational Cardiometabolic Genomic Medicine

Translational Cardiometabolic Genomic Medicine, edited by Dr. Annabelle Rodriguez-Oquendo, is an important resource to postgraduate (medical, dental and graduate) students, postdoctoral fellows, basic scientists, and physician scientists seeking to understand and expand their knowledge base in the field of genomic medicine as it is applied to cardiometabolic diseases. This handbook integrates cutting-edge experimental approaches such as chromatin immunoprecipitation paired end tagging (CHIA-PET), to population studies such as the Multi-Ethnic Study of Atherosclerosis. It encompasses a range of book chapters that

Nanobiosensors

Nanobiosensors
  • Author : Aiguo Wu,Waheed S. Khan
  • Publisher : John Wiley & Sons
  • Release : 11 February 2020
GET THIS BOOKNanobiosensors

Containing cutting edge research on the hot topic of nanobiosensor, this book will become highly read Biosensor research has recently re-emerged as most vibrant area in recent years particularly after the advent of novel nanomaterials of multidimensional features and compositions. Nanomaterials of different types and striking properties have played a positive role in giving the boost and accelerated pace to biosensors development technology. Nanobiosensors - From Design to Applications covers several aspects of biosensors beginning from the basic concepts to

Human Drug Metabolism

Human Drug Metabolism
  • Author : Michael D. Coleman
  • Publisher : John Wiley & Sons
  • Release : 19 February 2020
GET THIS BOOKHuman Drug Metabolism

Provides a timely update to a key textbook on human drug metabolism The third edition of this comprehensive book covers basic concepts of teaching drug metabolism, starting from extreme clinical consequences to systems and mechanisms and toxicity. It provides an invaluable introduction to the core areas of pharmacology and examines recent progress and advances in this fast moving field and its clinical impact. Human Drug Metabolism, 3rd Edition begins by covering basic concepts such as clearance and bioavailability, and looks

Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development

Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development
  • Author : Andrew J. Krentz,Lutz Heinemann,Marcus Hompesch
  • Publisher : Springer
  • Release : 29 November 2014
GET THIS BOOKTranslational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development

The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin secretion are fundamental to the pathogenesis and progression of obesity-associated type 2 diabetes. There

Breastfeeding and Human Lactation

Breastfeeding and Human Lactation
  • Author : Karen Wambach,Becky Spencer
  • Publisher : Jones & Bartlett Learning
  • Release : 01 October 2019
GET THIS BOOKBreastfeeding and Human Lactation

Breastfeeding and Human Lactation, Sixth Edition is the ultimate reference for the latest clinical techniques and research findings that direct evidence-based clinical practice for lactation consultants and specialists. It contains everything a nurse, lactation consultant, midwife, women’s health nurse practitioner, physician assistant, or Ob/Gyn needs to know about the subject. Topics include placing breastfeeding in its historical context, workplace-related issues, anatomical and biological imperatives of lactation, the prenatal and perinatal periods and concerns during the postpartum period, the

Epigenetics in Cardiovascular Disease

Epigenetics in Cardiovascular Disease
  • Author : Yvan Devaux,Emma Louise Robinson
  • Publisher : Academic Press
  • Release : 06 March 2021
GET THIS BOOKEpigenetics in Cardiovascular Disease

Epigenetics in Cardiovascular Disease, a new volume in the Translational Epigenetics series, offers a comprehensive overview of the epigenetics mechanisms governing cardiovascular disease development, as well as instructions in research methods and guidance in pursing new studies. More than thirty international experts provide an (i) overview of the epigenetics mechanisms and their contribution to cardiovascular disease development, (i) high-throughput methods for RNA profiling including single-cell RNA-seq, (iii) the role of nucleic acid methylation in cardiovascular disease development, (iv) epigenetic actors

Autophagy and Cardiometabolic Diseases

Autophagy and Cardiometabolic Diseases
  • Author : Jun Ren,James R. Sowers,Yingmei Zhang
  • Publisher : Academic Press
  • Release : 12 April 2018
GET THIS BOOKAutophagy and Cardiometabolic Diseases

Autophagy and Cardiometabolic Diseases: From Moleculer Mechanisms to Translational Medicine covers the science of autophagy in relation to cardiometabolic diseases and the future therapeutic potentials of autophagy regulation in these processes. Processes are not described in isolation, but in concert with other cellular and/or metabolic processes, such as lipogenesis, glucose, energy metabolism and apoptosis. This approach recognizes the multifactorial nature of cardiometabolic diseases, including obesity, diabetes, insulin resistance, hypertension and dyslipidemia. The book provides explanations, while also distinguishing the

Disease Control Priorities, Third Edition (Volume 5)

Disease Control Priorities, Third Edition (Volume 5)
  • Author : Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent
  • Publisher : World Bank Publications
  • Release : 17 November 2017
GET THIS BOOKDisease Control Priorities, Third Edition (Volume 5)

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge

Post-Genomic Cardiology

Post-Genomic Cardiology
  • Author : José Marín-García
  • Publisher : Academic Press
  • Release : 09 May 2014
GET THIS BOOKPost-Genomic Cardiology

In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome,” comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on

Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease

Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease
  • Author : Andrew J. Krentz,Christian Weyer,Marcus Hompesch
  • Publisher : Springer
  • Release : 02 April 2019
GET THIS BOOKTranslational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease

This book aims to aid the selection of the most appropriate methods for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, non-alcoholic fatty liver disease (NAFLD) and related cardiometabolic disorders. Clinical research methods to assess the pharmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycemic clamp technique, have become well-established in proof-of-mechanism studies. However, selection of the most appropriate techniques is by no means straightforward. Moreover, the application of such methods must conform

IOC Manual of Sports Cardiology

IOC Manual of Sports Cardiology
  • Author : Mathew G. Wilson,Jonathan A. Drezner,Sanjay Sharma
  • Publisher : John Wiley & Sons
  • Release : 19 December 2016
GET THIS BOOKIOC Manual of Sports Cardiology

For the practicing sports medicine physician at the front line of sports cardiology, this comprehensive and authoritative resource provides a centralized source of information which addresses this important topic in an accessible manner. This book recognises the broad role sports physicians play, from liaison between athlete, family, specialist, and coaching staff based on the identification of pathological heart disease, to being first to respond when an athlete collapses. The chapters include basic science of disease and disorders, pathophysiology, diagnosis, the

Achieving Justice in Genomic Translation

Achieving Justice in Genomic Translation
  • Author : Wylie Burke,Kelly A. Edwards,Sara Goering,Suzanne Holland,Susan Brown Trinidad
  • Publisher : Oxford University Press
  • Release : 15 September 2011
GET THIS BOOKAchieving Justice in Genomic Translation

This book examines ethical and social issues that arise in the conduct of genetic research, from the discovery phase, through development and delivery research, to health outcomes. The authors argue that research at every phase needs to be responsive to community needs to assure public health benefits and reduce, rather than exacerbate, health disparities.

Omics for Personalized Medicine

Omics for Personalized Medicine
  • Author : Debmalya Barh,Dipali Dhawan,Nirmal Kumar Ganguly
  • Publisher : Springer Science & Business Media
  • Release : 14 October 2013
GET THIS BOOKOmics for Personalized Medicine

“Omics for Personalized Medicine” will give to its prospective readers the insight of both the current developments and the future potential of personalized medicine. The book brings into light how the pharmacogenomics and omics technologies are bringing a revolution in transforming the medicine and the health care sector for the better. Students of biomedical research and medicine along with medical professionals will benefit tremendously from the book by gaining from the diverse fields of knowledge of new age personalized medicine