Tumor Microenvironment Regulation of Tumor Expansion

Tumor Microenvironment Regulation of Tumor Expansion is a practical guide to understand and perform research on tumor microenvironments, and to support related clinical decisions. Tumor progression is linked to an imbalance between positive and negative regulators, and mainly depends on the release of specific growth factors by inflammatory or neoplastic cells. Inflammatory infiltrate contributes to tumor progression and the metastatic process, and there are many reports of associations between tumor inflammatory infiltrate, progression, and prognosis. Understanding different contexts of organs is a key factor in improving treatment outcome, especially in new therapeutic treatments targeting components of the tumor microenvironment. This book is a valuable resource for cancer researchers, clinicians, graduate students, and scientists in many biomedical fields who are interested in the complex relationship between the tumor microenvironment and its context in specific organs. Provides a holistic approach to understanding the crucial role of the tumor microenvironment in tumor progression Encompasses the basic knowledge necessary to understand and undertake further studies related to tumor microenvironments Discusses new therapeutic approaches developed to control tumor progression by targeting different components of the tumor microenvironment

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  • Author : Domenico Ribatti
  • Publisher : Academic Press
  • Pages : 172 pages
  • ISBN : 0128228040
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKTumor Microenvironment Regulation of Tumor Expansion

Tumor Microenvironment Regulation of Tumor Expansion

Tumor Microenvironment Regulation of Tumor Expansion
  • Author : Domenico Ribatti
  • Publisher : Academic Press
  • Release : 04 April 2021
GET THIS BOOKTumor Microenvironment Regulation of Tumor Expansion

Tumor Microenvironment Regulation of Tumor Expansion is a practical guide to understand and perform research on tumor microenvironments, and to support related clinical decisions. Tumor progression is linked to an imbalance between positive and negative regulators, and mainly depends on the release of specific growth factors by inflammatory or neoplastic cells. Inflammatory infiltrate contributes to tumor progression and the metastatic process, and there are many reports of associations between tumor inflammatory infiltrate, progression, and prognosis. Understanding different contexts of organs

Stromal Cells

Stromal Cells
  • Author : Mani T. Valarmathi
  • Publisher : BoD – Books on Demand
  • Release : 23 January 2019
GET THIS BOOKStromal Cells

Stromal cells are connective tissue cells of any organ, and they support the function of the parenchymal cells of that particular organ. Stromal/stromal stem cells are fundamentally a heterogeneous population of cells with contradictory differentiation potential depending upon their environmental niche. Stromal cell biology is not only intriguing, but equally stromal cell ontogeny in vivo remains challenging. In recent years there has been substantial advances in our understanding of stromal cell biology, especially stromal cell isolation, characterization, differentiation, and

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor
  • Author : Terry Lichtor
  • Publisher : BoD – Books on Demand
  • Release : 25 March 2015
GET THIS BOOKMolecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor

A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular, recent new avenues regarding the role of microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to radiation therapy have been developed. A discussion of certain surgical management issues including improvements in imaging along with issues concerning tumor induced epilepsy is included. It is hopeful that this new

Resistance to Tyrosine Kinase Inhibitors

Resistance to Tyrosine Kinase Inhibitors
  • Author : Daniele Focosi
  • Publisher : Springer
  • Release : 07 November 2016
GET THIS BOOKResistance to Tyrosine Kinase Inhibitors

The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors.

Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy

Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy
  • Author : Pawel Kalinski
  • Publisher : Springer
  • Release : 22 December 2017
GET THIS BOOKTumor Immune Microenvironment in Cancer Progression and Cancer Therapy

The tumor microenvironment has become a very important and hot topic in cancer research within the past few years. The tumor microenvironment is defined as the normal cells, molecules, and blood vessels that surround and feed a tumor cell. As many scientists have realized, studying the tumor microenvironment has become critical to moving the field forward, since there are many players in a tumor’s localized and surrounding area, which can significantly change cancer cell behavior. There is a dual

Tumor Microenvironment

Tumor Microenvironment
  • Author : Alexander Birbrair
  • Publisher : Springer Nature
  • Release : 10 February 2020
GET THIS BOOKTumor Microenvironment

Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on non-hematopoietic cells within the tumor microenvironment.Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include fibroblasts, adipocytes, mesenchymal stem cells, stellate cells, and more. Taken alongside its companion volumes, Tumor Microenvironment: Non-Hematopoietic Cells updates us on what we know about the different aspects of the tumor microenvironment as well as future directions. Useful

Oncoimmunology

Oncoimmunology
  • Author : Laurence Zitvogel,Guido Kroemer
  • Publisher : Springer
  • Release : 13 December 2017
GET THIS BOOKOncoimmunology

In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches

Tumour Angiogenesis

Tumour Angiogenesis
  • Author : R. John Bicknell,Claire E. Lewis,Napoleone Ferrara
  • Publisher : Unknown Publisher
  • Release : 19 May 1997
GET THIS BOOKTumour Angiogenesis

Tumour Angiogenesis is the first comprehensive book to cover all areas of this rapidly expanding research area. Each chapter is written by world experts in the field and topics covered include in vivo models, mechanisms, inhibition, and the role of macrophages, cytokines, proteases,extracellular matrix components, nitric oxide, prostanoids and oncogenes/tumour suppressor genes in angiogenesis. Other chapters examine the role of specific growth factors in angiogenesis - these include vascular endothelial growth factor, the basic fibroblast growth factor family,

Biomarkers of the Tumor Microenvironment

Biomarkers of the Tumor Microenvironment
  • Author : Lars A. Akslen,Randolph S. Watnick
  • Publisher : Springer
  • Release : 02 August 2017
GET THIS BOOKBiomarkers of the Tumor Microenvironment

This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Practical applications, in terms of how biomarkers are increasingly included in therapy protocols, will also be discussed. Biomarkers of the Tumour Microenvironment: Basic Studies and Practical Applications is aimed at research pathologists in the cancer field, and also cancer researchers from other backgrounds, especially those using morphology techniques and models focusing on cross-talk between different cell types in tumors.

Tumor Microenvironment

Tumor Microenvironment
  • Author : Alexander Birbrair
  • Publisher : Springer Nature
  • Release : 25 June 2020
GET THIS BOOKTumor Microenvironment

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research in the field. A variety of topics are covered, including metabolism in the tumor microenvironment, stellate cells and endothelial progenitors in the tumor microenvironment, as well as the effects of HIV, viral hepatitis, and inflammation in the tumor microenvironment, and more. Taken alongside its companion volumes, Tumor Microenvironment: State of the Science updates us on what we know about various

Tumor Microenvironment

Tumor Microenvironment
  • Author : Peter P. Lee,Francesco M. Marincola
  • Publisher : Springer Nature
  • Release : 25 March 2020
GET THIS BOOKTumor Microenvironment

This book addresses the biological processes relevant to the immune phenotypes of cancer and their significance for immune responsiveness, based on the premise that malignant cells manipulate their surroundings through an evolutionary process that is controlled by interactions with innate immune sensors as well as the adaptive recognition of self/non-self. Checkpoint inhibitor therapy is now an accepted new form of cancer treatment. Other immuno-oncology approaches, such as adoptive cell therapy and metabolic inhibitors, have also shown promising results for

Physics of Cancer

Physics of Cancer
  • Author : Claudia Mierke
  • Publisher : Iph001
  • Release : 24 October 2018
GET THIS BOOKPhysics of Cancer

This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.

Tumor Progression and Therapeutic Resistance

Tumor Progression and Therapeutic Resistance
  • Author : Wafik S. El-Deiry
  • Publisher : Unknown Publisher
  • Release : 19 May 2021
GET THIS BOOKTumor Progression and Therapeutic Resistance

This volume presents the entire breadth of translational cancer research and brings together members of academia and industry in the expectation of accelerating interactions and progress in the field. A variety of key topics are presented, beginning with discovery of molecular targets and pathways (oncogene, cell survival, tumor suppression, cell death), host-neoplasm interactions (cell adhesion, matrix proteases), early detection, monitoring progression, understanding tumor progression and metastasis, immune surveillance, in vivo molecular imaging, animal models, drug discovery including chemistry, high-throughput assays,