Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine

Umbilical cord blood (UCB) and, more recently, umbilical cord tissue (UCT) have been stored cryopreserved in private and public cord blood and tissue banks worldwide, since the umbilical cord blood was used for the first time in a child with Fanconi anemia with his HLA-identical sibling, following strict guidelines that imply high-quality standards and total rastreability of these units. The hematopoietic stem cells (HSCs) are clinically used in hematopoietic treatments for blood disorders and hemato-oncological diseases. Also, the mesenchymal stem cells (MSCs) isolated from the UCT and UCB, nowadays, can be used as coadjuvants of hematopoietic transplants. In the near future, these stem cells will have a crucial role in regenerative medicine. For this reason, these cells have been tested in several clinical trials and compassive treatments in children and adults, concerning a wide range of pathologies and diseases, for instance, for the treatment of cerebral paralysis. Considering the worldwide availability of UCB and UCT units and the absence of ethical concerns will probably become the best sources for cell-based therapies for hematological and nonhematological pathologies. The UCB will also have a crucial role in neonatology-predictive analysis in the near future.

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  • Author : Ana Colette Maurício
  • Publisher : BoD – Books on Demand
  • Pages : 258 pages
  • ISBN : 9535128655
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKUmbilical Cord Blood Banking for Clinical Application and Regenerative Medicine

Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine

Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine
  • Author : Ana Colette Maurício
  • Publisher : BoD – Books on Demand
  • Release : 11 January 2017
GET THIS BOOKUmbilical Cord Blood Banking for Clinical Application and Regenerative Medicine

Umbilical cord blood (UCB) and, more recently, umbilical cord tissue (UCT) have been stored cryopreserved in private and public cord blood and tissue banks worldwide, since the umbilical cord blood was used for the first time in a child with Fanconi anemia with his HLA-identical sibling, following strict guidelines that imply high-quality standards and total rastreability of these units. The hematopoietic stem cells (HSCs) are clinically used in hematopoietic treatments for blood disorders and hemato-oncological diseases. Also, the mesenchymal stem

Cord Blood Stem Cells Medicine

Cord Blood Stem Cells Medicine
  • Author : Catherine Stavropoulos-Giokas,Dominique Charron,Cristina Navarrete
  • Publisher : Elsevier
  • Release : 03 December 2014
GET THIS BOOKCord Blood Stem Cells Medicine

Cord Blood Stem Cells and Regenerative Medicine discusses the current applications for cord blood stem cells and techniques for banking cord blood. Cord blood, blood from the umbilical cord and placenta of an infant, represents an alternate source of stem cells that can be used to treat a myriad of disorders. Cord blood stem cells are being used more frequently and studied more seriously, as evidenced by the explosion of scientific literature on the topic. Currently, clinical and pre-clinical trials

Cord Blood

Cord Blood
  • Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Establishing a National Cord Blood Stem Cell Bank Program
  • Publisher : National Academies Press
  • Release : 26 November 2005
GET THIS BOOKCord Blood

With the potential for self-renewal and differentiation, the possibilities for stem cells are enormous. One specific type of stem cell, the hematopoietic progenitor cell (HPC), which is derived from umbilical cord blood (as well as adult bone marrow and mobilized peripheral blood), holds particular promise. To make the most of these HPCs, the Institute of Medicine was asked to consider the optimal structure for a national cord blood program and to address pertinent issues related to maximizing the potential of

Perinatal Stem Cells

Perinatal Stem Cells
  • Author : Anthony Atala,Kyle J. Cetrulo,Rouzbeh R. Taghizadeh,Curtis L Cetrulo,Sean Murphy
  • Publisher : Academic Press
  • Release : 14 June 2018
GET THIS BOOKPerinatal Stem Cells

Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton’s jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases,

Umbilical Cord Blood Banking and Transplantation

Umbilical Cord Blood Banking and Transplantation
  • Author : Karen Ballen
  • Publisher : Springer
  • Release : 12 August 2014
GET THIS BOOKUmbilical Cord Blood Banking and Transplantation

This comprehensive volume discusses the current scope of umbilical cord blood transplantation (UCBT), including recent controversies and future developments for improving clinical outcomes. Its twenty chapters introduce new applications in regenerative medicine and discuss the latest scientific, regulatory, clinical and investigational aspects of cord blood banking. Physicians from around the world provide a global collaboration which explores strategies for umbilical cord blood expansion, homing, unit selection, and combining of graft sources to improve patient outcomes. Umbilical Cord Blood Banking and

Stem Cell Processing

Stem Cell Processing
  • Author : Phuc Van Pham
  • Publisher : Springer
  • Release : 18 October 2016
GET THIS BOOKStem Cell Processing

This invaluable resource delineates procedures for development and use of stem cells in the laboratory and explores the potential for clinical applications. The text discusses mesenchymal stem cell isolation, isolation of adipose derived stem cells, new trends of induced pluripotent stem cells in disease treatment, cord blood banking, future directions of the discussed therapies and much more. The chapters are contributed by preeminent scientists in the field and present a comprehensive picture of stem cell processes, from development in the

Novel Perspectives of Stem Cell Manufacturing and Therapies

Novel Perspectives of Stem Cell Manufacturing and Therapies
  • Author : Diana Kitala,Ana Colette Maurício
  • Publisher : BoD – Books on Demand
  • Release : 14 April 2021
GET THIS BOOKNovel Perspectives of Stem Cell Manufacturing and Therapies

In the 1950s, Nobel Prize winner Dr. E. Donnall Thomas was the first to successfully transplant hematopoietic stem cells. Since then, studies on stem cells have evolved and expanded worldwide. There are more than 650,000 scientific publications on stem cells and more than 8000 stem cell clinical trials. This book summarizes types of stem cells, key studies, ongoing trials, and future perspectives. It also includes ethical, formal, and legal aspects to give the reader a comprehensive view of the field.

Umbilical Cord Blood

Umbilical Cord Blood
  • Author : Suzanne Kadereit
  • Publisher : World Scientific
  • Release : 01 March 2010
GET THIS BOOKUmbilical Cord Blood

Umbilical cord blood, previously discarded after birth, has emerged over recent years as an alternative source of hematopoietic stem cells for hematological reconstitution, mainly for leukemia patients, as well as for some hematological deficiencies and bone marrow failures. In recent years, it has become increasingly clear that cord blood, as well as the surrounding tissue of the umbilical cord, contain additional stem cells which have been shown to be of great potential for regenerative medicine. Importantly, cord blood is abundant,

The EBMT Handbook

The EBMT Handbook
  • Author : Nicolaus Kröger,Mohamad Mohty,Carlo Dufour
  • Publisher : Unknown Publisher
  • Release : 08 October 2020
GET THIS BOOKThe EBMT Handbook

This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and

Stem Cells and the Future of Regenerative Medicine

Stem Cells and the Future of Regenerative Medicine
  • Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
  • Publisher : National Academies Press
  • Release : 25 January 2002
GET THIS BOOKStem Cells and the Future of Regenerative Medicine

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush’s watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a

Peripheral Nerve Regeneration

Peripheral Nerve Regeneration
  • Author : Ana Colette Maurício
  • Publisher : BoD – Books on Demand
  • Release : 31 May 2017
GET THIS BOOKPeripheral Nerve Regeneration

Peripheral nerve injuries are a high-incidence clinical problem that greatly affects patients' quality of life. Despite continuous refinement of microsurgery techniques, peripheral nerve repair still stands as one of the most challenging tasks in neurosurgery, as functional neuromuscular recovery is rarely satisfactory in these patients. Therefore, the improvement of surgical techniques and the clinical application of innovative therapies have been intensively studied worldwide. Direct nerve repair with epineural end-to-end sutures is still the gold standard treatment for severe neurotmesis injuries

Stem Cell Banking

Stem Cell Banking
  • Author : Dusko Ilic
  • Publisher : Springer
  • Release : 05 May 2014
GET THIS BOOKStem Cell Banking

This book exemplifies experience across the globe in banking of cord blood, mesenchymal, embryonic and induced pluripotent stem cells for clinical use from the United States, Canada, the European Union, Switzerland and Japan to Iran, India and Serbia. The concerns are similar regardless of stem cell type or origin. Implementing core values and common standards depend often on specific circumstances of political and economic setting, which makes flexibility as important as systematic planning. Banking of stem cells is not just

Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
  • Author : Lucas G. Chase,Mohan C Vemuri
  • Publisher : Springer Science & Business Media
  • Release : 12 December 2012
GET THIS BOOKMesenchymal Stem Cell Therapy

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host

Recent Advances in Stem Cells

Recent Advances in Stem Cells
  • Author : Essam M. Abdelalim
  • Publisher : Springer
  • Release : 14 September 2016
GET THIS BOOKRecent Advances in Stem Cells

This volume explores recent advances in the use of pluripotent stem cells (PSCs) and adult stem cells (ASCs) in basic and clinical applications. The chapters discuss use of PSCs for drug screening, genome editing, modeling of kidney, motor neuron diseases, and diabetes as well as their application in cancer; ASCs are discussed in the contexts of banking of umbilical cord stem cells, use of multipotential stromal cells (MSCs) for bone repair, cellular interactions during fracture repair stages, and therapeutic applications