Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment describes the historical evolution of quantitative structure-activity relationship (QSAR) approaches and their fundamental principles. This book includes clear, introductory coverage of the statistical methods applied in QSAR and new QSAR techniques, such as HQSAR and G-QSAR. Containing real-world examples that illustrate important methodologies, this book identifies QSAR as a valuable tool for many different applications, including drug discovery, predictive toxicology and risk assessment. Written in a straightforward and engaging manner, this is the ideal resource for all those looking for general and practical knowledge of QSAR methods. Includes numerous practical examples related to QSAR methods and applications Follows the Organization for Economic Co-operation and Development principles for QSAR model development Discusses related techniques such as structure-based design and the combination of structure- and ligand-based design tools

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  • Author : Kunal Roy
  • Publisher : Academic Press
  • Pages : 484 pages
  • ISBN : 0128016337
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKUnderstanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment
  • Author : Kunal Roy,Supratik Kar,Rudra Narayan Das
  • Publisher : Academic Press
  • Release : 03 March 2015
GET THIS BOOKUnderstanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment describes the historical evolution of quantitative structure-activity relationship (QSAR) approaches and their fundamental principles. This book includes clear, introductory coverage of the statistical methods applied in QSAR and new QSAR techniques, such as HQSAR and G-QSAR. Containing real-world examples that illustrate important methodologies, this book identifies QSAR as a valuable tool for many different applications, including drug discovery, predictive toxicology and risk assessment. Written in a straightforward

Methods and Algorithms for Molecular Docking-Based Drug Design and Discovery

Methods and Algorithms for Molecular Docking-Based Drug Design and Discovery
  • Author : Dastmalchi, Siavoush
  • Publisher : IGI Global
  • Release : 03 May 2016
GET THIS BOOKMethods and Algorithms for Molecular Docking-Based Drug Design and Discovery

The role of technology in the medical field has resulted in significant developments within the pharmaceutical industry. Computational approaches have emerged as a crucial method in further advancing drug design and development. Methods and Algorithms for Molecular Docking-Based Drug Design and Discovery presents emerging research on the application of computer-assisted design methods for drugs, emphasizing the benefits and improvements that molecular docking has caused within the pharmaceutical industry. Focusing on validation methods, search algorithms, and scoring functions, this book is

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Artificial Neural Network for Drug Design, Delivery and Disposition
  • Author : Munish Puri,Yashwant Pathak,Vijay Kumar Sutariya,Srinivas Tipparaju,Wilfrido Moreno
  • Publisher : Academic Press
  • Release : 15 October 2015
GET THIS BOOKArtificial Neural Network for Drug Design, Delivery and Disposition

Artificial Neural Network for Drug Design, Delivery and Disposition provides an in-depth look at the use of artificial neural networks (ANN) in pharmaceutical research. With its ability to learn and self-correct in a highly complex environment, this predictive tool has tremendous potential to help researchers more effectively design, develop, and deliver successful drugs. This book illustrates how to use ANN methodologies and models with the intent to treat diseases like breast cancer, cardiac disease, and more. It contains the latest

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Engineering Tools in the Beverage Industry
  • Author : Alexandru Grumezescu,Alina-Maria Holban
  • Publisher : Woodhead Publishing
  • Release : 08 February 2019
GET THIS BOOKEngineering Tools in the Beverage Industry

Engineering Tools in the Beverage Industry, Volume Three in The Science of Beverages series, is an invaluable resource for anyone in the beverages field who is involved with quality assurance, lab analysis, and the safety of beverage products. The book offers updates on the latest techniques and applications, including extraction, biochemical isotope analysis, metabolomics, microfiltration, and encapsulation. Users will find this book to be an excellent resource for industrial research in an ever-changing field. Provides practical tools and techniques for

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  • Author : Huixiao Hong
  • Publisher : Springer
  • Release : 21 May 2019
GET THIS BOOKAdvances in Computational Toxicology

This book provides a comprehensive review of both traditional and cutting-edge methodologies that are currently used in computational toxicology and specifically features its application in regulatory decision making. The authors from various government agencies such as FDA, NCATS and NIEHS industry, and academic institutes share their real-world experience and discuss most current practices in computational toxicology and potential applications in regulatory science. Among the topics covered are molecular modeling and molecular dynamics simulations, machine learning methods for toxicity analysis, network-based

Advances in QSAR Modeling

Advances in QSAR Modeling
  • Author : Kunal Roy
  • Publisher : Springer
  • Release : 22 May 2017
GET THIS BOOKAdvances in QSAR Modeling

The book covers theoretical background and methodology as well as all current applications of Quantitative Structure-Activity Relationships (QSAR). Written by an international group of recognized researchers, this edited volume discusses applications of QSAR in multiple disciplines such as chemistry, pharmacy, environmental and agricultural sciences addressing data gaps and modern regulatory requirements. Additionally, the applications of QSAR in food science and nanoscience have been included – two areas which have only recently been able to exploit this versatile tool. This timely addition

Genotoxicity

Genotoxicity
  • Author : Marcelo Larramendy,Sonia Soloneski
  • Publisher : BoD – Books on Demand
  • Release : 11 July 2018
GET THIS BOOKGenotoxicity

This book is designed to provide an overview of the different genotoxicants and their effects on living organisms, including humans. The contributions made by the specialists in this field of research are gratefully acknowledged. We hope that the information presented in this book will meet the expectations and needs of all those interested in the different aspects of the genotoxicity field. The publication of this book is of great importance to those scientists, pharmacologists, physicians and veterinarians, as well as

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Agri-Food Supply Chain Management: Breakthroughs in Research and Practice
  • Author : Management Association, Information Resources
  • Publisher : IGI Global
  • Release : 27 September 2016
GET THIS BOOKAgri-Food Supply Chain Management: Breakthroughs in Research and Practice

The development of a sustainable agricultural system is a critical concern for any nation in modern society. By implementing proper supply chain processes, available natural resources and food can be better utilized. Agri-Food Supply Chain Management: Breakthroughs in Research and Practice is a compendium of emerging perspectives on the development of an effective agricultural value chain and the optimization of supply chain management within the agriculture and food sectors. Highlighting theoretical frameworks, real-world applications, and future outlooks, this book is

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  • Author : James Njuguna,Krzysztof Pielichowski,Huijun Zhu
  • Publisher : Woodhead Publishing
  • Release : 24 July 2021
GET THIS BOOKHealth and Environmental Safety of Nanomaterials

Health and Environmental Safety of Nanomaterials: Polymer Nanocomposites and other Materials Containing Nanoparticles, Second Edition updates on new developments in the field of nanomaterials safety, both at release and exposure. The book covers the advanced modeling approaches that are helping to elucidate nano-risks by addressing (quantitative) structure-activity relationships, the modeling of the interaction of nanoparticles with biological (macro) molecules, biochemical pathways and systems and/or the analysis of biomolecular signatures and the development of biomarkers suitable to characterize the impact

Multivariate Analysis in the Pharmaceutical Industry

Multivariate Analysis in the Pharmaceutical Industry
  • Author : Ana Patricia Ferreira,Jose C. Menezes,Mike Tobyn
  • Publisher : Academic Press
  • Release : 24 April 2018
GET THIS BOOKMultivariate Analysis in the Pharmaceutical Industry

Multivariate Analysis in the Pharmaceutical Industry provides industry practitioners with guidance on multivariate data methods and their applications over the lifecycle of a pharmaceutical product, from process development, to routine manufacturing, focusing on the challenges specific to each step. It includes an overview of regulatory guidance specific to the use of these methods, along with perspectives on the applications of these methods that allow for testing, monitoring and controlling products and processes. The book seeks to put multivariate analysis into

Oncology: Breakthroughs in Research and Practice

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  • Author : Management Association, Information Resources
  • Publisher : IGI Global
  • Release : 29 June 2016
GET THIS BOOKOncology: Breakthroughs in Research and Practice

Advancements in cancer diagnosis and treatment have extended the lives of many patients facing numerous types of cancer over the years. Research on best practices, new drug development, early identification, and treatment continues to advance with the ultimate goal of uncovering a cure for cancer in all its forms. Oncology: Breakthroughs in Research and Practice features international perspectives on cancer identification, treatment, and management methodologies in addition to patient considerations and outlooks for the future. This collection of emerging research

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  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release : 18 November 2016
GET THIS BOOKDrug Safety Evaluation

This practical guide presents a road map for safety assessment as an integral part of the development of new drugs and therapeutics. Helps readers solve scientific, technical, and regulatory issues in preclinical safety assessment and early clinical drug development Explains scientific and philosophical bases for evaluation of specific concerns – including local tissue tolerance, target organ toxicity and carcinogenicity, developmental toxicity, immunogenicity, and immunotoxicity Covers the development of new small and large molecules, generics, 505(b)(2) route NDAs, and biosimilars Revises material

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  • Author : Iqbal Ahmad,Shamim Ahmad,Kendra P. Rumbaugh
  • Publisher : Springer Nature
  • Release : 09 November 2019
GET THIS BOOKAntibacterial Drug Discovery to Combat MDR

This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques

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  • Author : Agnieszka Gajewicz,Tomasz Puzyn
  • Publisher : CRC Press
  • Release : 13 November 2019
GET THIS BOOKComputational Nanotoxicology

The development of computational methods that support human health and environmental risk assessment of engineered nanomaterials (ENMs) has attracted great interest because the application of these methods enables us to fill existing experimental data gaps. However, considering the high degree of complexity and multifunctionality of ENMs, computational methods originally developed for regular chemicals cannot always be applied explicitly in nanotoxicology. This book discusses the current state of the art and future needs in the development of computational modeling techniques for